Search Results - "Seefeldt, Carolin A."

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  1. 1

    Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome by Seefeldt, A Carolin, Graf, Michael, Pérébaskine, Natacha, Nguyen, Fabian, Arenz, Stefan, Mardirossian, Mario, Scocchi, Marco, Wilson, Daniel N, Innis, C Axel

    Published in Nucleic acids research (18-03-2016)
    “…Proline-rich antimicrobial peptides (PrAMPs) produced as part of the innate immune response of animals, insects and plants represent a vast, untapped resource…”
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  2. 2

    Ornithine capture by a translating ribosome controls bacterial polyamine synthesis by Herrero del Valle, Alba, Seip, Britta, Cervera-Marzal, Iñaki, Sacheau, Guénaël, Seefeldt, A. Carolin, Innis, C. Axel

    Published in Nature microbiology (01-04-2020)
    “…Polyamines are essential metabolites that play an important role in cell growth, stress adaptation and microbial virulence 1 – 3 . To survive and multiply…”
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  3. 3

    Proline-rich antimicrobial peptides targeting protein synthesis by Graf, Michael, Mardirossian, Mario, Nguyen, Fabian, Seefeldt, A Carolin, Guichard, Gilles, Scocchi, Marco, Innis, C Axel, Wilson, Daniel N

    Published in Natural product reports (01-07-2017)
    “…Covering: up to 2017The innate immune system employs a broad array of antimicrobial peptides (AMPs) to attack invading microorganisms. While most AMPs act by…”
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  4. 4

    Publisher Correction: Ornithine capture by a translating ribosome controls bacterial polyamine synthesis by del Valle, Alba Herrero, Seip, Britta, Cervera-Marzal, Iñaki, Sacheau, Guénaël, Seefeldt, A. Carolin, Innis, C. Axel

    Published in Nature microbiology (01-04-2020)
    “…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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  5. 5

    Real-time measurements of aminoglycoside effects on protein synthesis in live cells by Rivera, Javier Aguirre, Larsson, Jimmy, Volkov, Ivan L., Seefeldt, A. Carolin, Sanyal, Suparna, Johansson, Magnus

    “…The spread of antibiotic resistance is turning many of the currently used antibiotics less effective against common infections. To address this public health…”
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  6. 6

    Direct Measurements of Erythromycin’s Effect on Protein Synthesis Kinetics in Living Bacterial Cells by Seefeldt, A. Carolin, Aguirre Rivera, Javier, Johansson, Magnus

    Published in Journal of molecular biology (14-05-2021)
    “…[Display omitted] •Direct kinetics measurements of erythromycin’s effect on ongoing protein synthesis.•Translation elongation is slowed down in bacterial cells…”
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  7. 7

    Tracking of single tRNAs for translation kinetics measurements in chloramphenicol treated bacteria by Volkov, Ivan L., Seefeldt, A. Carolin, Johansson, Magnus

    Published in Methods (San Diego, Calif.) (01-06-2019)
    “…•Single tRNA tracking allows kinetics studies of ongoing translation in live cells.•tRNAs bind dynamically to chloramphenicol inhibited…”
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  8. 8

    The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex by Seefeldt, A Carolin, Nguyen, Fabian, Antunes, Stéphanie, Pérébaskine, Natacha, Graf, Michael, Arenz, Stefan, Inampudi, K Kishore, Douat, Céline, Guichard, Gilles, Wilson, Daniel N, Innis, C Axel

    Published in Nature structural & molecular biology (01-06-2015)
    “…Structural and biochemical studies reveal how the antimicrobial peptide Onc112 binds to bacterial ribosomes and show that Onc112 blocks and destabilizes the…”
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  9. 9

    Notch-signalling is required for head regeneration and tentacle patterning in Hydra by Münder, Sandra, Tischer, Susanne, Grundhuber, Maresa, Büchels, Nathalie, Bruckmeier, Nadine, Eckert, Stefanie, Seefeldt, Carolin A., Prexl, Andrea, Käsbauer, Tina, Böttger, Angelika

    Published in Developmental biology (01-11-2013)
    “…Local self-activation and long ranging inhibition provide a mechanism for setting up organising regions as signalling centres for the development of structures…”
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