Search Results - "Seefeldt, Carolin A."
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Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome
Published in Nucleic acids research (18-03-2016)“…Proline-rich antimicrobial peptides (PrAMPs) produced as part of the innate immune response of animals, insects and plants represent a vast, untapped resource…”
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Ornithine capture by a translating ribosome controls bacterial polyamine synthesis
Published in Nature microbiology (01-04-2020)“…Polyamines are essential metabolites that play an important role in cell growth, stress adaptation and microbial virulence 1 – 3 . To survive and multiply…”
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Proline-rich antimicrobial peptides targeting protein synthesis
Published in Natural product reports (01-07-2017)“…Covering: up to 2017The innate immune system employs a broad array of antimicrobial peptides (AMPs) to attack invading microorganisms. While most AMPs act by…”
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Publisher Correction: Ornithine capture by a translating ribosome controls bacterial polyamine synthesis
Published in Nature microbiology (01-04-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Real-time measurements of aminoglycoside effects on protein synthesis in live cells
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2021)“…The spread of antibiotic resistance is turning many of the currently used antibiotics less effective against common infections. To address this public health…”
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Direct Measurements of Erythromycin’s Effect on Protein Synthesis Kinetics in Living Bacterial Cells
Published in Journal of molecular biology (14-05-2021)“…[Display omitted] •Direct kinetics measurements of erythromycin’s effect on ongoing protein synthesis.•Translation elongation is slowed down in bacterial cells…”
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Tracking of single tRNAs for translation kinetics measurements in chloramphenicol treated bacteria
Published in Methods (San Diego, Calif.) (01-06-2019)“…•Single tRNA tracking allows kinetics studies of ongoing translation in live cells.•tRNAs bind dynamically to chloramphenicol inhibited…”
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The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex
Published in Nature structural & molecular biology (01-06-2015)“…Structural and biochemical studies reveal how the antimicrobial peptide Onc112 binds to bacterial ribosomes and show that Onc112 blocks and destabilizes the…”
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Notch-signalling is required for head regeneration and tentacle patterning in Hydra
Published in Developmental biology (01-11-2013)“…Local self-activation and long ranging inhibition provide a mechanism for setting up organising regions as signalling centres for the development of structures…”
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Kurze Peptide regulieren die Aktivität bakterieller Ribosomen
Published in Biospektrum (01-09-2017)Get full text
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