Search Results - "Seebach, Dieter"

Generation of Secondary, Tertiary, and Quaternary Centers by Geminal Disubstitution of Carbonyl Oxygens by Seebach, Dieter

“…Methods for replacing the carbonyl oxygen by two new substituents (CO→CR1R2) are discussed in this Minireview, whereby R may be H, NR2, alkyl, allyl, benzyl,…”
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Structures and function of the amino acid polymerase cyanophycin synthetase by Sharon, Itai, Haque, Asfarul S., Grogg, Marcel, Lahiri, Indrajit, Seebach, Dieter, Leschziner, Andres E., Hilvert, Donald, Schmeing, T. Martin

“…Cyanophycin is a natural biopolymer produced by a wide range of bacteria, consisting of a chain of poly- l -Asp residues with l -Arg residues attached to the…”
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Joy and flustration with organofluorine compounds - a fluorous autobiography by Seebach, Dieter

“…An overview is given about our work on fluoro-organic compounds, published or described in PhD theses between 1977 and 2013. After a discussion of structural…”
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Organocatalyzed Michael Addition of Aldehydes to Nitro Alkenes - Generally Accepted Mechanism Revisited and Revised by Patora-Komisarska, Krystyna, Benohoud, Meryem, Ishikawa, Hayato, Seebach, Dieter, Hayashi, Yujiro

“…The amine‐catalyzed enantioselective Michael addition of aldehydes to nitro alkenes (Scheme 1) is known to be acid‐catalyzed (Fig. 1). A mechanistic…”
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A journey from the pool of chiral synthetic building blocks to cell-penetrating peptides, to a novel type of enzyme - and back by Seebach, Dieter

“…The roles of polyhydroxy-butyrates/alkanoates (PHB/PHA) in biology, for the preparation of chiral building blocks, and as a source of inspiration for the…”
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A Theoretical and Experimental Study of the Effects of Silyl Substituents in Enantioselective Reactions Catalyzed by Diphenylprolinol Silyl Ether by Hayashi, Yujiro, Okamura, Daichi, Yamazaki, Tatsuya, Ameda, Yasuto, Gotoh, Hiroaki, Tsuzuki, Seiji, Uchimaru, Tadafumi, Seebach, Dieter

“…The effect of silyl substituents in diphenylprolinol silyl ether catalysts was investigated. Mechanistically, reactions catalyzed by diphenylprolinol silyl…”
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Improved Efficacy of Fosmidomycin against Plasmodium and Mycobacterium Species by Combination with the Cell-Penetrating Peptide Octaarginine by SPARR, Christof, PURKAYASTHA, Nirupam, KOLESINSKA, Beata, GENGENBACHER, Martin, AMULIC, Borko, MATUSCHEWSKI, Kai, SEEBACH, Dieter, KAMENA, Faustin

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Are Oxazolidinones Really Unproductive, Parasitic Species in Proline Catalysis? - Thoughts and Experiments Pointing to an Alternative View by Seebach, Dieter, Beck, Albert K., Badine, D. Michael, Limbach, Michael, Eschenmoser, Albert, Treasurywala, Adi M., Hobi, Reinhard, Prikoszovich, Walter, Linder, Bernard

“…The N,O‐acetal and N,O‐ketal derivatives (oxazolidinones) formed from proline, and aldehydes or ketones are well‐known today, and they are detectable in…”
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Swiss Chemical Society – Syngenta Symposium: Frontiers in Fluorine Chemistry by Ryan Gilmour, Dieter Seebach

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Probing the interactions of an acyl carrier protein domain from the 6‐deoxyerythronolide B synthase by Charkoudian, Louise K., Liu, Corey W., Capone, Stefania, Kapur, Shiven, Cane, David E., Togni, Antonio, Seebach, Dieter, Khosla, Chaitan

“…The assembly‐line architecture of polyketide synthases (PKSs) provides an opportunity to rationally reprogram polyketide biosynthetic pathways to produce novel…”
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No Life on this Planet Without PHB by Seebach, Dieter

“…The history of discovery by Rosetta Reusch of oligo‐ and poly‐β‐hydroxybutyrates (OHBs and PHBs) consisting of less than ca. 150 HB units is described. These…”
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5-Benzyl-3-methylimidazolidin-4-one-Derived Reactive Intermediates of Organocatalysis - A Comforting Resemblance of X-Ray, NMR, and DFT Solid-Phase, Liquid-Phase, and Gas-Phase Structures by Grošelj, Uroš, Schweizer, W. Bernd, Ebert, Marc-Olivier, Seebach, Dieter

“…The X‐ray crystal structures of three (E)‐1‐cinnamoylidene iminium PF6 salts of 5‐benzyl‐3‐methylimidazolidin‐4‐ones (2,2‐dimethyl‐, cis‐2‐(tert‐butyl)‐, and…”
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Artificial Chemokines: Combining Chemistry and Molecular Biology for the Elucidation of Interleukin-8 Functionality by David, Ralf, Günther, Robert, Baumann, Lars, Lühmann, Tessa, Seebach, Dieter, Hofmann, Hans-Jörg, Beck-Sickinger, Annette G

“…How can we understand the contribution of individual parts or segments to complex structures? A typical strategy to answer this question is simulation of a…”
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Experimental and Theoretical Conformational Analysis of 5-Benzylimidazolidin-4-one Derivatives - a 'Playground' for Studying Dispersion Interactions and a 'Windshield-Wiper' Effect in Organocatalysis by Seebach, Dieter, Grošelj, Uroš, Schweizer, W. Bernd, Grimme, Stefan, Mück-Lichtenfeld, Christian

“…The PF6 salts of 5‐benzyl‐1‐isopropylidene‐ and 5‐benzyl‐1‐cinnamylidene‐3‐methylimidazolidin‐4‐ones 1 (Scheme) with various substituents in the 2‐position…”
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β-Peptidic Peptidomimetics by Seebach, Dieter, Gardiner, James

“…For more than a decade now, a search for answers to the following two questions has taken us on a new and exciting journey into the world of β- and γ-peptides:…”
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Dendritic TADDOLs: Synthesis, Characterization and Use in the Catalytic Enantioselective Addition of Et2Zn to Benzaldehyde by Rheiner, P. Beat, Seebach, Dieter

“…Novel chiral dendritic catalysts carrying a TADDOL unit in their centers have been synthesized and fully characterized (1). The titanates of the dendritic…”
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Enantiomeric and Diastereoisomeric (Mixed) L/ D-Octaarginine Derivatives - A Simple Way of Modulating the Properties of Cell-Penetrating Peptides by Purkayastha, Nirupam, Eyer, Klaus, Robinson, Tom, Dittrich, Petra S., Beck, Albert K., Seebach, Dieter, Kolesinska, Beata, Cadalbert, Riccardo

“…Cell‐penetrating peptides (CPPs) are promising vehicles for delivery of drugs, antibiotics, proteins, nucleic acid derivatives, etc. into eukaryotic and…”
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Teruaki Mukaiyama (1927–2018) by Seebach, Dieter

“…Teruaki Mukaiyama, formerly Professor at Tokyo Institute of Technology, Tokyo University, and Tokyo University of Science passed away on November 17, 2018. As…”
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Albert Karl Beck's 60th birthday – Thanks to him for the past 40 years the Seebach group has kept functioning Albert Karl Beck wurde 60 – Fast nichts lief ohne ihn für 40 Jahre in der Arbeitsgruppe Seebach by Dieter Seebach

“…Albert K. Beck celebrated his 60th birthday on January 18, 2007. He has been a member of the Seebach group since 1968 and was involved in essentially all areas…”
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Preparation of Enantiomerically Pure Compounds Employing Anodic Oxidations of Carboxylic Acids – A Late Review of Research Done in the 1980ies by Seebach, Dieter

“…There are widely unknown enantiopure building blocks and non‐conventional transformations described in this old work that could become useful in today's…”
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