Search Results - "Sedzik, Jan"

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  1. 1

    Glycans of myelin proteins by Sedzik, Jan, Jastrzebski, Jan Pawel, Grandis, Marina

    Published in Journal of neuroscience research (01-01-2015)
    “…Human P0 is the main myelin glycoprotein of the peripheral nervous system. It can bind six different glycans, all linked to Asn93, the unique glycosylation…”
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    Journal Article
  2. 2

    GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system by Yoshimura, Takeshi, Hayashi, Akiko, Handa-Narumi, Mai, Yagi, Hirokazu, Ohno, Nobuhiko, Koike, Takako, Yamaguchi, Yoshihide, Uchimura, Kenji, Kadomatsu, Kenji, Sedzik, Jan, Kitamura, Kunio, Kato, Koichi, Trapp, Bruce D., Baba, Hiroko, Ikenaka, Kazuhiro

    Published in Scientific reports (10-02-2017)
    “…Highly specialized glial cells wrap axons with a multilayered myelin membrane in vertebrates. Myelin serves essential roles in the functioning of the nervous…”
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  3. 3

    Sequence motifs of myelin membrane proteins: Towards the molecular basis of diseases by Sedzik, Jan, Jastrzebski, Jan Pawel, Ikenaka, Kazuhiro

    Published in Journal of neuroscience research (01-04-2013)
    “…The shortest sequence of amino acids in protein containing functional and structural information is a “motif.” To understand myelin protein functions, we…”
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  4. 4

    Myelin sheaths and autoimmune response induced by myelin proteins and alphaviruses. I. Physicochemical background by Sedzik, Jan

    Published in Current medicinal chemistry (01-08-2008)
    “…Myelin proteins of the central and peripheral nervous system range from very hydrophilic to extremely hydrophobic proteins. Their biological function and…”
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  5. 5

    Tetrameric Assembly of Full-Sequence Protein Zero Myelin Glycoprotein by Synchrotron X-Ray Scattering by Inouye, Hideyo, Tsuruta, Hiro, Sedzik, Jan, Uyemura, Keiichi, Kirschner, Daniel A.

    Published in Biophysical journal (1999)
    “…Highly purified myelin P0 glycoprotein was solubilized to 1–8 mg/ml in 0.1% sodium dodecyl sulfate (SDS), and the solution structure of the P0 assembly was…”
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  6. 6

    Towards crystallization of hydrophobic myelin glycoproteins: P0 and PASII/PMP22 by Sedzik, Jan, Uyemura, Keiichi, Tsukihara, Tomitake

    Published in Protein expression and purification (01-12-2002)
    “…The preparation of a pure and homogeneous protein sample at proper concentration is a prerequisite for success when attempting their crystallization for…”
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  7. 7

    High-resolution structural model of porcine P2 myelin membrane protein with associated fatty acid ligand: Fact or artifact? by Sedzik, Jan, Jastrzebski, Jan Pawel

    Published in Journal of neuroscience research (01-06-2011)
    “…Myelin membrane is a biological complex of glial cells origin; it is composed of 25% (w/w) proteins and 75% lipids, and more than 300 proteins are associated…”
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    Porcine P2 myelin protein primary structure and bound fatty acids determined by mass spectrometry by Maddalo, Gianluca, Shariatgorji, Mohammadreza, Adams, Christopher M, Fung, Eva, Nilsson, Ulrika, Zubarev, Roman A, Sedzik, Jan, Ilag, Leopold L

    Published in Analytical and bioanalytical chemistry (01-07-2010)
    “…Complementary collision-induced/electron capture dissociation Fourier-transform ion cyclotron resonance mass spectrometry was used to fully sequence the…”
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    Solubilization of PNS myelin membrane proteins by detergents by Sedzik, Jan, Tsukihara, Tomitake

    Published in Neuroreport (03-08-2000)
    “…We have applied 25 different detergents to the PNS myelin membrane. The extracts produced were analyzed regarding the total amount of protein solubilized, and…”
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  18. 18

    Crystals of P2 myelin protein in lipid-bound form by Sedzik, Jan, Carlone, Giulia, Fasano, Anna, Liuzzi, Grazia Maria, Riccio, Paolo

    Published in Journal of structural biology (01-05-2003)
    “…The P2 protein of peripheral nervous system myelin induces experimental allergic neuritis in rats, a model of Guillain–Barré syndrome in humans. Previous…”
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  19. 19

    Factorially designed crystallization trials of the full-length P0 myelin membrane glycoprotein. I. Precipitation diagram by Sedzik, Jan, Kotake, Yoshiko, Uyemura, Keiichi, Ataka, Mitsuo

    Published in Journal of crystal growth (2003)
    “…P0 glycoprotein is the abundant membrane protein of myelin of the peripheral nervous system. We report now the statistical design of the crystallization…”
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    Purification of P0 myelin glycoprotein by a cu2+-immobilized metal affinity chromatography by SEDZIK, J, KOTAKE, Y, UYEMURA, K

    Published in Neurochemical research (01-06-1999)
    “…P0 is an abundant myelin glycoprotein of peripheral nerves of vertebrates. Various point mutations of this protein are responsible for hereditary neuropathies…”
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