Search Results - "Sedgwick, J.B."

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    Eosinophil Adhesion to Junctional Adhesion Molecules In Vitro by Cook, E.B, Stahl, J.L, Fox, K.E, Sedgwick, J.B, Barney, N.P, Graziano, F.M

    Published in Journal of allergy and clinical immunology (01-02-2008)
    “…Results Unstimulated eosinophil adhesion to recombinant JAM-A, B, or C was increased compared to uncoated wells (p < 0.05). [...]eosinophils stimulated with…”
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    Journal Article
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    Urokinase-type Plasminogen Activator (uPA) Primes FMLP-Activated Airway Eosinophil (EOS) Adhesion to ICAM-1 and VCAM-1 Following Segmental Bronchoprovocation with Allergen (SBP-AG) by Brooks, A.M., Sedgwick, J.B.

    Published in Journal of allergy and clinical immunology (01-02-2006)
    “…METHODS: 48h after SBP-AG of allergic asthma patients, EOS were isolated from bronchoalveolar lavage fluid and peripheral blood by density gradient and…”
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    Journal Article
  4. 4

    Sputum vs bronchoalveolar lavage (BAL) eosinophils (EOS) as markers of airway dysfunction in asthma by Sedgwick, J.B., Swenson, C.A., Busse, W.W.

    Published in Journal of allergy and clinical immunology (01-02-2005)
    “…Furthermore, they suggest that it is airway hyperresponsiveness that has a closer association with %EOS, raising the possibility that the EOS contribution to…”
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    Journal Article
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    Human Eosinophils Enhance Staphylococcal Enterotoxin B Stimulation of CD4+ T-cells by Mathur, S.K., Durocher, E.A., Liu, L., Kelly, E.A.B., Sedgwick, J.B., Jarjour, N.N., Busse, W.W.

    Published in Journal of allergy and clinical immunology (01-02-2006)
    “…RATIONALE: Since both Staphylococcal enterotoxin B (SEB) and eosinophils (EOS) have been implicated in the pathogenesis of allergic diseases such as atopic…”
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    Ocular Olopatadine Treatment of Seasonal Allergic Conjunctivitis Decreases the Ability of Tears to Promote In Vitro Eosinophil Adhesion to Tear-Stimulated Conjun ctival Epithelial Cells by Cook, E.B., Stahl, J.L., Sedgwick, J.B., Brooks, A.M., Graziano, F.M., Barney, N.P.

    Published in Journal of allergy and clinical immunology (01-02-2006)
    “…Olopatadine treatment significantly inhibited the ability of tears to promote eosinophil adhesion resulting in a net decrease of 486.84 ±116.45 eosinophils/cm2…”
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    Airway eosinophil (EOS) expression of urokinase-type plasminogen activator receptor (uPAR) following segmental allergen challenge correlates with airway reactivity of patients with asthma by Brooks, A.M., Bates, M., Vrtis, R.F., Busse, W.W., Sedgwick, J.B.

    Published in Journal of allergy and clinical immunology (01-02-2005)
    “…[...]uPAR expressed by BAL EOS 48h-post allergen challenge had a strong inverse correlation with airway hyperresponsiveness (methacholine PC20) of the…”
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  8. 8

    Relationship of in vitro survival and eosinophil derived neurotoxin (EDN) degranulation in blood and airway eosinophils (EOS) following segmental bronchoprovocation with allergen (SBP-AG) by Sedgwick, J.B., Bartemes, K., Kita, H., Busse, W.W.

    Published in Journal of allergy and clinical immunology (01-02-2004)
    “…EOS isolated from blood and bronchoalveolar lavage fluid (BAL) 48h post-SBP-AG of allergic asthmatic (AA) patients differ in function. Although both…”
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    VLA-4 antagonist WAY160103 (WAY) inhibits VCAM-1 activated eosinophil (EOS) respiratory burst but promotes eosinophil derived neurotoxin (EDN) degranulation by Brooks, A.M., Sedgwick, J.B., Jansen, K.J., Kita, H., Squillace, D., Kennedy, J.D., Busse, W.W.

    Published in Journal of allergy and clinical immunology (01-02-2004)
    “…EOS are selectively recruited to the lung during asthma exacerbations and play an important role in airway inflammation. EOS participation is initiated by…”
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  11. 11

    Human eosinophils express IL-18 mRNA and protein by Mathur, S.K., Sedgwick, J.B., Vrtis, R.F., Brooks, A.M., Busse, W.W.

    Published in Journal of allergy and clinical immunology (01-02-2004)
    “…The role and contribution of eosinophils to allergic inflammation is under re-evaluation and may include activities that regulate lymphocyte function. For…”
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    Journal Article
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