Search Results - "Sedelmeier, Jörg"

Synthesis of Vildagliptin Utilizing Continuous Flow and Batch Technologies by Pellegatti, Laurent, Sedelmeier, Jörg

“…The preparation and utilization of the Vilsmeier reagent (VR) is well-known in the literature with its usefulness and scope being frequently demonstrated in…”
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Development of a Continuous Flow Grignard Reaction to Manufacture a Key Intermediate of Ipatasertib by Kaldre, Dainis, Stocker, Severin, Linder, David, Reymond, Helena, Schuster, Andreas, Lamerz, Jens, Hildbrand, Stefan, Püntener, Kurt, Berry, Malcolm, Sedelmeier, Jörg

“…This article outlines the development of a continuous flow process for the manufacture of a key intermediate of the active pharmaceutical ingredient…”
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KMnO4-Mediated Oxidation as a Continuous Flow Process by Sedelmeier, Jörg, Ley, Steven V, Baxendale, Ian R, Baumann, Marcus

“…An efficient and easily scalable transformation of alcohols and aldehydes to carboxylic acids and nitroalkane derivatives to the corresponding carbonyls and…”
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A Multistep Flow Process for the Synthesis of Highly Functionalized Benzoxazoles by Sedelmeier, Jörg, Lima, Fabio, Litzler, Alain, Martin, Benjamin, Venturoni, Francesco

“…An efficient and scalable transformation of 3-halo-N-acyl anilines to the corresponding benzoxazoles within a continuous flow reactor is reported. This…”
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C1-symmetric oxazolinyl sulfoximines as ligands in copper-catalyzed asymmetric mukaiyama aldol reactions by Sedelmeier, Jörg, Hammerer, Tim, Bolm, Carsten

“…Aryl-bridged C1-symmetric oxazolinyl sulfoximines are applicable in copper-catalyzed asymmetric Mukaiyama aldol reactions with methyl pyruvate. The resulting…”
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C 1-Symmetric Oxazolinyl Sulfoximines as Ligands in Copper-Catalyzed Asymmetric Mukaiyama Aldol Reactions by Sedelmeier, Jörg, Hammerer, Tim, Bolm, Carsten

“…Aryl-bridged C 1-symmetric oxazolinyl sulfoximines are applicable in copper-catalyzed asymmetric Mukaiyama aldol reactions with methyl pyruvate. The resulting…”
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Multi-Step Synthesis by Using Modular Flow Reactors: The Preparation of YneOnes and Their Use in Heterocycle Synthesis by Baxendale, Ian R., Schou, Søren C., Sedelmeier, Jörg, Ley, Steven V.

“…Multi‐step in flow: The palladium‐catalysed acylation of terminal alkynes for the synthesis of yneones as well as their further transformation to various…”
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A Two-Step Continuous-Flow Procedure towards Ribociclib by Pellegatti, Laurent, Hafner, Andreas, Sedelmeier, Jörg

“…This work describes the manufacturing of ribociclib following the concept of an end-to-end continuous-flow process. The active pharmaceutical ingredient (API)…”
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Efficient Copper-Catalyzed N-Arylation of Sulfoximines with Aryl Iodides and Aryl Bromides by Sedelmeier, Jörg, Bolm, Carsten

“…Two simple and inexpensive systems for copper-catalyed N-arylations of sulfoximines with aryl bromides and aryl iodides have been developed. Using 10 mol % of…”
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Application of β-Hydroxysulfoximines in Catalytic Asymmetric Phenyl Transfer Reactions for the Synthesis of Diarylmethanols by Sedelmeier, Jörg, Bolm, Carsten

“…Enantiomerically enriched diarylmethanols have been prepared by catalyzed asymmetric phenyl transfer reactions onto aromatic aldehydes with use of readily…”
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Pd-EnCat™ TPP30 as a Catalyst for the Generation of Highly Functionalized Aryl- and Alkenyl-Substituted Acetylenes via Microwave-Assisted Sonogashira Type Reactions by SEDELMEIER, Jörg, LEY, Steven V, LANGE, Heiko, BAXENDALE, Ian R

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KMnO 4 -Mediated Oxidation as a Continuous Flow Process by Sedelmeier, Jörg, Ley, Steven V., Baxendale, Ian R., Baumann, Marcus

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Multi-Step Synthesis by Using Modular Flow Reactors: The Preparation of YneOnes and Their Use in Heterocycle Synthesis by Baxendale, IanR, Schou, SørenC, Sedelmeier, Jörg, Ley, StevenV

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Pd‐EnCat TM TPP30 as a Catalyst for the Generation of Highly Functionalized Aryl‐ and Alkenyl‐Substituted Acetylenes via Microwave‐Assisted Sonogashira Type Reactions by Sedelmeier, Jörg, Ley, Steven V., Lange, Heiko, Baxendale, Ian R.

“…We report a rapid microwave‐assisted Sonogashira cross‐coupling of aryl iodides and bromides with terminal alkynes using Pd‐EnCat TM TPP30. Both electron‐rich…”
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KMnO(4)-Mediated oxidation as a continuous flow process by Sedelmeier, Jörg, Ley, Steven V, Baxendale, Ian R, Baumann, Marcus

“…An efficient and easily scalable transformation of alcohols and aldehydes to carboxylic acids and nitroalkane derivatives to the corresponding carbonyls and…”
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Top 200 Drugs by Worldwide Sales 2016 by Gottfried Sedelmeier, Joerg Sedelmeier

“…The poster series of the Top 200 Drugs by Worldwide Sales by G. Sedelmeier and J. Sedelmeier has now been updated with an overview of the top selling drugs in…”
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Pd‐EnCatTM TPP30 as a Catalyst for the Generation of Highly Functionalized Aryl‐ and Alkenyl‐Substituted Acetylenes via Microwave‐Assisted Sonogashira Type Reactions by Sedelmeier, Jörg, Ley, Steven V., Lange, Heiko, Baxendale, Ian R.

“…We report a rapid microwave‐assisted Sonogashira cross‐coupling of aryl iodides and bromides with terminal alkynes using Pd‐EnCatTM TPP30. Both electron‐rich…”
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