Search Results - "Seddon, Benedict P."

ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation by Pearson, Claire, Thornton, Emily E, McKenzie, Brent, Schaupp, Anna-Lena, Huskens, Nicky, Griseri, Thibault, West, Nathaniel, Tung, Sim, Seddon, Benedict P, Uhlig, Holm H, Powrie, Fiona

“…Innate lymphoid cells (ILCs) contribute to host defence and tissue repair but can induce immunopathology. Recent work has revealed tissue-specific roles for…”
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Tissue specific deletion of inhibitor of kappa B kinase 2 with OX40-Cre reveals the unanticipated expression from the OX40 locus in skin epidermis by Cornish, Georgina H, Tung, Sim L, Marshall, Daniel, Ley, Steve, Seddon, Benedict P

“…NF-κB signalling plays an essential role in T cell activation and generation of regulatory and memory populations in vivo. In the present study, we aimed to…”
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Evidence of STAT5-dependent and -independent routes to CD8 memory formation and a preferential role for IL-7 over IL-15 in STAT5 activation by Kemp, Roslyn A, Pearson, Claire F, Cornish, Georgina H, Seddon, Benedict P

“…Interleukin (IL)‐7 and IL‐15 have non‐redundant roles in promoting development of memory CD8+ T cells. STAT5 is activated by receptors of both cytokines and…”
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71 Alone is not Sufficient for IL-7-Receptor-Dependent Generation and Maintenance of CD8+ Memory T cells by Kemp, Roslyn A., Seddon, Benedict P.

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The Role of the Thymus in the Control of Autoimmunity by Heath, Victoria L., Saoudi, Abdelhadi, Seddon, Benedict P., Moore, Nel C., Fowell, Deborah J., Mason, Don W.

“…Self tolerance among T cells is believed to be maintained by two principal mechanisms: clonal deletion for self antigens expressed in the thymus and T cell…”
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