Search Results - "Secher, Niels Henry"
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Ischemic Preconditioning of One Forearm Enhances Static and Dynamic Apnea
Published in Medicine and science in sports and exercise (01-01-2014)“…INTRODUCTIONIschemic preconditioning enhances ergometer cycling and swimming performance. We evaluated whether ischemic preconditioning of one forearm (four…”
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2
Glucagon-to-insulin ratio is pivotal for splanchnic regulation of FGF-21 in humans
Published in Molecular metabolism (Germany) (01-08-2015)“…Abstract Background & aims Fibroblast growth factor 21 (FGF-21) is a liver-derived metabolic regulator induced by energy deprivation. However, its regulation…”
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3
Cerebral oxygenation during exercise in patients with terminal lung disease
Published in Chest (01-08-2002)“…In patients with terminal lung disease who were exercising, we assessed whether improved arterial O2 saturation with an increased fraction of inspired oxygen…”
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4
The effect of hepatectomy on glucose homeostasis in pig and in man
Published in Journal of hepatology (2002)“…Background/Aims : The liver is regarded the most important source of glucose production and it is common practice to administer glucose during human liver…”
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5
Time Trial Performance Is Sensitive to Low-Volume Autologous Blood Transfusion
Published in Medicine and science in sports and exercise (01-04-2019)“…PURPOSEThis study tested the hypothesis that autologous blood transfusion (ABT) of ~50% of the red blood cells (RBC) from a standard 450-mL phlebotomy would…”
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Sodium Nitroprusside Induced Vasodilatation Encompasses Cerebral Blood Flow in Young Men
Published in The FASEB journal (01-04-2018)“…Purpose Sodium nitroprusside (SNP) reduces blood pressure by vasodilatation, but is reported to lower cerebral blood flow (CBF). We evaluated the influence of…”
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Cerebral lactate uptake during exercise is driven by the increased arterial lactate concentration
Published in Journal of applied physiology (1985) (01-12-2021)“…Exercise facilitates cerebral lactate uptake, likely by increasing arterial lactate concentration and hence the diffusion gradient across the blood-brain…”
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8
Detection of Autologous Blood Transfusion by Metabolomics
Published in The FASEB journal (01-04-2020)“…Abstract only…”
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Cerebral Hyperperfusion and Metabolic Regulation in Response to Hypoxia: Do ATP‐Sensitive Potassium Channels Play a Role?
Published in The FASEB journal (01-04-2018)“…ATP‐sensitive K+ channels (K+ATP) mediate hypoxia‐induced cerebral vasodilatation and hyperperfusion in animals, a compensatory mechanism that maintains the…”
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Matrix Metalloproteinase Mediated Type I Collagen Degradation is an Independent Predictor of Increased Risk of Acute Myocardial Infarction in Postmenopausal Women
Published in Scientific reports (29-03-2018)“…Acute myocardial infarction (AMI) is often underdiagnosed in women. It is therefore of interest to identify biomarkers that indicate increased risk of AMI and…”
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Cerebral Hypoperfusion and Metabolic Regulation during Isocapnic Hyperoxia: The Role of Reactive Oxygen Species
Published in The FASEB journal (01-04-2018)“…Introduction Hyperoxia provokes cerebral hypoperfusion but its impact on regional cerebrovascular responses and brain metabolism remains unclear. While a…”
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Protocol for a multicentre retrospective observational cohort study in Denmark: association between the intraoperative peripheral perfusion index and postoperative morbidity and mortality in acute non-cardiac surgical patients
Published in BMJ open (21-11-2019)“…IntroductionPerioperative haemodynamic instability is associated with postoperative morbidity and mortality. Macrocirculatory parameters, such as arterial…”
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13
Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study
Published in International journal of chronic obstructive pulmonary disease (01-01-2016)“…Exercise is an important countermeasure to limb muscle dysfunction in COPD. The two major training modalities in COPD rehabilitation, endurance training (ET)…”
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Elevated Renal Oxygen Extraction During Open Abdominal Aortic Aneurysm Repair Is Related to Postoperative Renal Dysfunction
Published in Seminars in cardiothoracic and vascular anesthesia (01-12-2018)“…Background. Open abdominal aortic aneurysm repair is often followed by elevated plasma creatinine, likely due to impaired renal blood flow. We evaluated…”
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Cutaneous blood flow influences near infrared spectroscopy evaluation of frontal lobe oxygenation by approximately 30
Published in The FASEB journal (01-04-2013)“…Abstract only Frontal lobe cerebral oxygenation (s c O 2 ) is assessed by spatially resolved near infrared spectroscopy (SR‐NIRS) to exclude the contribution…”
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Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anesthesia: an open label randomized controlled trial
Published in Frontiers in physiology (2014)“…During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine…”
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O2 supplementation to secure the near-infrared spectroscopy determined brain and muscle oxygenation in vascular surgical patients: a presentation of 100 cases
Published in Frontiers in physiology (2014)“…This study addresses three questions for securing tissue oxygenation in brain (rScO2) and muscle (SmO2) for 100 patients (age 71 ± 6 years; mean ± SD)…”
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Human brain is oxidizing substantial quantities of lactate under basal and hyperlactatemic conditions
Published in The FASEB journal (01-04-2008)“…Neurons have been suggested to utilize lactate as their main energy substrate, the lactate originating from astrocytes and the circulation. Indeed, human…”
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The brain does not take up lactate during exercise in hypoxia
Published in The FASEB journal (2007)“…Cerebral function depends on continuous oxygen delivery, but whether the brain has a potential for anaerobic metabolism is not known. The brain has a small net…”
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