Search Results - "Sechelski, J"

Restoring ciliary function to differentiated primary ciliary dyskinesia cells with a lentiviral vector by Ostrowski, L E, Yin, W, Patel, M, Sechelski, J, Rogers, T, Burns, K, Grubb, B R, Olsen, J C

“…Primary ciliary dyskinesia (PCD) is a genetically heterogenous autosomal recessive disease in which mutations disrupt ciliary function, leading to impaired…”
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The Individual Host, a Unique Evolutionary Island for Rapidly Dividing Parasites: A Theoretical Approach by Seed, John R., Sechelski, John B.

“…It is hypothesized that rapidly dividing parasites producing high parasitemias within an individual host are in different environmental settings. It is further…”
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The Inheritance of Factors Controlling Resistance in Mice Infected with Trypanosoma brucei rhodesiense by Seed, J. R., Sechelski, J.

“…In crosses between 2 recombinant inbred strains of mice (B x H-2 and B x H-14), resistance to infection with Trypanosoma brucei rhodesiense as measured by…”
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Mechanism of Lysis of Trypanosoma brucei gambiense by Human Serum by Ortiz-Ordóñez, Juan Carlos, Sechelski, John B., Seed, John R.

“…Resistance to lysis by human serum (HS) is an important parameter used to distinguish Trypanosoma brucei brucei from both Trypanosoma brucei rhodesiense and…”
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Characterization of Human Serum-Resistant and Serum-Sensitive Clones from a Single Trypanosoma brucei gambiense Parental Clone by Ortiz, Juan Carlos, Sechelski, John B., Seed, John R.

“…A protocol was developed to select clones of Trypanosoma brucei gambiense having different levels of resistance to normal human serum. Human serum-resistant…”
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Relationship between Human Serum Trypanocidal Activity and Host Resistance to the African Trypanosomes by Seed, John R., Sechelski, John B., Ortiz, Juan Carlos, Chapman, John F.

“…Results reported here show that humans have various levels of trypanocidal activity in their sera. This difference appeared stable when different samples were…”
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Nature of the Trypanocidal Factor in Human Serum by Seed, John Richard, Sechelski, John B.

“…The chemical nature of the trypanocidal factor in human serum was investigated. The results show that although the trypanocidal factor is contained within the…”
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Growth of pleomorphic Trypanosoma brucei rhodesiense in irradiated inbred mice by Seed, John R., Sechelski, John

“…It was shown that irradiation (650 rad) of 7 inbred strains of mice did not block the ability of Trypanosoma brucei rhodesiense to transform from the long…”
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African trypanosomes: inheritance of factors involved in resistance by Seed, J R, Sechelski, J B

“…The C3HeB/FeJ mouse strain has a shorter survival time and is therefore more susceptible to a Trypanosoma brucei rhodesiense infection than the B10.BR/SgSnJ…”
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A survey for a trypanocidal factor in primate sera by Seed, J R, Sechelski, J B, Loomis, M R

“…The sera of 21 different species of primates were surveyed for the presence of a trypanocidal factor to a monomorphic human serum-sensitive clone of…”
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Trypanosoma brucei rhodesiense: the inhibition of HL-60 cell growth by the African trypanosomes in vitro by Keku, T O, Seed, J R, Sechelski, J B, Balber, A

“…Trypanosomiasis is of major public health importance in Africa where the disease affects man and livestock. In order to explore the underlying mechanisms of…”
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Immune response to minor variant antigen types (VATs) in a mixed VAT infection of the African trypanosomes by Seed, J R, Sechelski, J B

“…It has been shown that soon after the onset of acute infection with Trypanosoma brucei gambiense, mice are able to detect immunologically small numbers of…”
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Multiple alpha-keto aciduria in Microtus montanus chronically infected with Trypanosoma brucei gambiense by Hall, J E, Seed, J R, Sechelski, J B

“…Microtus montanus chronically infected with a monomorphic strain of Trypanosoma brucei gambiense excreted in urine greatly elevated quantities of not only the…”
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Further biochemical characterization of chronic Trypanosoma brucei gambiense-Microtus montanus infection by Seed, J R, Sechelski, J, Hall, J E

“…Tyrosine aminotransferase (TAT), glutamic-pyruvic transaminase (GPT), glutamic-oxaloacetic transaminase (GOT), and alkaline phosphatase (ALP) were measured in…”
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The role of antibody in African trypanosomiasis by Seed, J.R, Sechelski, J

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Use of sodium butyrate to enhance production of retroviral vectors expressing CFTR cDNA by Olsen, J C, Sechelski, J

“…Previously, we constructed a retrovirus vector (LCFSN) for transduction and expression of the cDNA encoding the normal human cystic fibrosis transmembrane…”
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Mechanism of long slender (LS) to short stumpy (SS) transformation in the African trypanosomes by Seed, J R, Sechelski, J B

“…The transformation of the long slender to the short stumpy stages of the African trypanosomes is an essential part of the trypanosome life cycle. Four possible…”
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Tryptophol levels in mice injected with pharmacological doses of tryptophol, and the effect of pyrazole and ethanol on these levels by Seed, J R, Sechelski, J

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Changes in albumin levels in blood and urine of Microtus montanus chronically infected with Trypanosoma brucei gambiense by Frommel, T.O, Seed, J.R, Sechelski, J

“…Serum albumin and glucose concentrations and urinary excretion of alpha-keto acids and proteins were determined in samples obtained throughout a chronic…”
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The ecology of antigenic variation by Seed, J R, Edwards, R, Sechelski, J

“…A detailed molecular analysis using recombinant DNA technologies is extremely important to our understanding of the phenomena of antigenic variation in the…”
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