Search Results - "Sebkhi, A."

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  1. 1

    Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension by SEBKHI, A, STRANGE, Julian W, PHILLIPS, Steven C, WHARTON, John, WILKINS, Martin R

    Published in Circulation (New York, N.Y.) (01-07-2003)
    “…Phosphodiesterase type 5 (PDE5) is a novel therapeutic target for the treatment of pulmonary hypertension. This study examined the distribution of PDE5 in…”
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    Journal Article
  2. 2

    Simvastatin and sildenafil combine to attenuate pulmonary hypertension by Zhao, L, Sebkhi, A, Ali, O, Wojciak-Stothard, B, Mamanova, L, Yang, Q, Wharton, J, Wilkins, M. R

    Published in The European respiratory journal (01-10-2009)
    “…Statins have been proposed to be a potential treatment for pulmonary arterial hypertension. If introduced into clinical practice, the statin would have to be…”
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    Journal Article
  3. 3

    A refined radio-telemetry technique to monitor right ventricle or pulmonary artery pressures in rats: a useful tool in pulmonary hypertension research by Handoko, M. L., Schalij, I., Kramer, K., Sebkhi, A., Postmus, P. E., van der Laarse, W. J., Paulus, W. J., Vonk-Noordegraaf, A.

    Published in Pflügers Archiv (01-02-2008)
    “…Implantable radio-telemetry methodology, allowing for continuous recording of pulmonary haemodynamics, has previously been used to assess effects of therapy on…”
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    Journal Article
  4. 4

    Angiotensin II receptor expression and inhibition in the chronically hypoxic rat lung by Zhao, Lan, Al‐Tubuly, Rida, Sebkhi, Abdelkrim, Owji, Ali A., Nunez, Derek J.R., Wilkins, Martin R.

    Published in British journal of pharmacology (01-11-1996)
    “…1 Angiotensin II (All) binding density and the effect of chronic All receptor blockade were examined in the rat model of hypoxia‐induced pulmonary…”
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    Journal Article
  5. 5

    Endometrial electrogenic ion secretion in the rat is modulated by prostaglandins by Sebkhi, A, Levin, R J

    Published in Experimental physiology (01-05-1990)
    “…In the isolated rat uterus, maximal increases in endometrial electrogenic ion secretion produced by luminal prostaglandins (PGs) E1, E2 and F1, and measured as…”
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    Journal Article
  6. 6

    Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17 : Evaluation of cardiac ryanodine Ryr2 receptor as a candidate by LAN ZHAO, SEBKHI, Abdelkrim, NUNEZ, Derek J. R, LU LONG, HALEY, Christopher S, SZPIRER, Josiane, SZPIRER, Claude, WILLIAMS, Alan J, WILKINS, Martin R

    Published in Circulation (New York, N.Y.) (23-01-2001)
    “…Fischer 344 (F344) rats are relatively resistant to hypoxia-induced right ventricular (RV) hypertrophy compared with the Wistar-Kyoto (WKY) strain. These 2…”
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    Journal Article
  7. 7

    Effect of Age on the Pattern of Short-term Albumin Uptake by the Rabbit Aortic Wall Near Intercostal Branch Ostia by Sebkhi, Abdelkrim, Weinberg, Peter D

    “…Lipid deposition occurs more frequently downstream than upstream of branches in immature human aorta but the opposite pattern is seen in mature vessels. These…”
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  8. 8

    Age-related variations in transport properties of the rabbit arterial wall near branches by Sebkhi, A, Weinberg, P D

    Published in Atherosclerosis (01-03-1994)
    “…Lipid accumulation in the human aorta occurs predominantly downstream of branches in foetuses, neonates and infants but upstream at later ages. The lipid in…”
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    Journal Article
  9. 9

    Genetic Determination of Cardiac Mass in Normotensive Rats: Results From an F344xWKY Cross by Sebkhi, Abdelkrim, Zhao, Lan, Lu, Long, Haley, Christopher S, Nunez, Derek J.R, Wilkins, Martin R

    Published in Hypertension (Dallas, Tex. 1979) (01-04-1999)
    “…Genetic determinants affect adult cardiac mass and the predisposition to develop cardiac hypertrophy. The aim of this study was to identify quantitative trait…”
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    Journal Article Conference Proceeding