Search Results - "Sebire, Neil J."

Placental pathology in early-onset and late-onset fetal growth restriction by Mifsud, William, Sebire, Neil J

“…Several histopathological features are found more frequently in placentas from pregnancies complicated by fetal growth restriction (FGR), including villous…”
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Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition by Pereira, Branca I., Devine, Oliver P., Vukmanovic-Stejic, Milica, Chambers, Emma S., Subramanian, Priya, Patel, Neil, Virasami, Alex, Sebire, Neil J., Kinsler, Veronica, Valdovinos, Alexis, LeSaux, Claude Jourdan, Passos, João F., Antoniou, Antony, Rustin, Malcom H. A., Campisi, Judith, Akbar, Arne N.

“…Senescent cells accumulate in human tissues during ageing and contribute to age-related pathologies. The mechanisms responsible for their accumulation are…”
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Gestational trophoblastic disease by Seckl, Michael J, Prof, Sebire, Neil J, FRCPath, Berkowitz, Ross S, MD

“…Summary Gestational trophoblastic disease encompasses a range of pregnancy-related disorders, consisting of the premalignant disorders of complete and partial…”
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Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial by Norman, Jane Elizabeth, Prof, Marlow, Neil, Prof, Messow, Claudia-Martina, PhD, Shennan, Andrew, Prof, Bennett, Phillip R, Prof, Thornton, Steven, Prof, Robson, Stephen C, Prof, McConnachie, Alex, PhD, Petrou, Stavros, Prof, Sebire, Neil J, Prof, Lavender, Tina, Prof, Whyte, Sonia, MSc, Norrie, John, Prof

“…Summary Background Progesterone administration has been shown to reduce the risk of preterm birth and neonatal morbidity in women at high risk, but there is…”
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Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds by Campinoti, Sara, Gjinovci, Asllan, Ragazzini, Roberta, Zanieri, Luca, Ariza-McNaughton, Linda, Catucci, Marco, Boeing, Stefan, Park, Jong-Eun, Hutchinson, John C., Muñoz-Ruiz, Miguel, Manti, Pierluigi G., Vozza, Gianluca, Villa, Carlo E., Phylactopoulos, Demetra-Ellie, Maurer, Constance, Testa, Giuseppe, Stauss, Hans J., Teichmann, Sarah A., Sebire, Neil J., Hayday, Adrian C., Bonnet, Dominique, Bonfanti, Paola

“…The thymus is a primary lymphoid organ, essential for T cell maturation and selection. There has been long-standing interest in processes underpinning thymus…”
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A global review of publicly available datasets for ophthalmological imaging: barriers to access, usability, and generalisability by Khan, Saad M, Liu, Xiaoxuan, Nath, Siddharth, Korot, Edward, Faes, Livia, Wagner, Siegfried K, Keane, Pearse A, Sebire, Neil J, Burton, Matthew J, Denniston, Alastair K

“…Health data that are publicly available are valuable resources for digital health research. Several public datasets containing ophthalmological imaging have…”
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Human fetal whole-body postmortem microfocus computed tomographic imaging by Simcock, Ian C., Shelmerdine, Susan C., Hutchinson, J. Ciaran, Sebire, Neil J., Arthurs, Owen J.

“…Perinatal autopsy is the standard method for investigating fetal death; however, it requires dissection of the fetus. Human fetal microfocus computed…”
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Multiple Congenital Melanocytic Nevi and Neurocutaneous Melanosis Are Caused by Postzygotic Mutations in Codon 61 of NRAS by Kinsler, Veronica A., Thomas, Anna C., Ishida, Miho, Bulstrode, Neil W., Loughlin, Sam, Hing, Sandra, Chalker, Jane, McKenzie, Kathryn, Abu-Amero, Sayeda, Slater, Olga, Chanudet, Estelle, Palmer, Rodger, Morrogh, Deborah, Stanier, Philip, Healy, Eugene, Sebire, Neil J., Moore, Gudrun E.

“…Congenital melanocytic nevi (CMN) can be associated with neurological abnormalities and an increased risk of melanoma. Mutations in NRAS, BRAF, and Tp53 have…”
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EMA/CO for High-Risk Gestational Trophoblastic Neoplasia: Good Outcomes With Induction Low-Dose Etoposide-Cisplatin and Genetic Analysis by ALIFRANGIS, Constantine, AGARWAL, Roshan, SHORT, Delia, FISHER, Rosemary A, SEBIRE, Neil J, HARVEY, Richard, SAVAGE, Philip M, SECKL, Michael J

“…Patients with high-risk (International Federation of Gynecology and Obstetrics score ≥ 7) gestational trophoblastic neoplasia (GTN) frequently receive…”
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Review of study reporting guidelines for clinical studies using artificial intelligence in healthcare by Shelmerdine, Susan Cheng, Arthurs, Owen J, Denniston, Alastair, Sebire, Neil J

“…High-quality research is essential in guiding evidence-based care, and should be reported in a way that is reproducible, transparent and where appropriate,…”
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Intensified therapies improve survival and identification of novel prognostic factors for placental-site and epithelioid trophoblastic tumours by Froeling, Fieke E. M., Ramaswami, Ramya, Papanastasopoulos, Panagiotis, Kaur, Baljeet, Sebire, Neil J., Short, Dee, Fisher, Rosemary A., Sarwar, Naveed, Wells, Michael, Singh, Kam, Ellis, Laura, Horsman, Janet M., Winter, Matthew C., Tidy, John, Hancock, Barry W., Seckl, Michael J.

“…Background Placental-site trophoblastic (PSTT) and epithelioid trophoblastic tumours (ETT) are the rarest malignant forms of gestational trophoblastic disease…”
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"We might get a lot more families who will agree": Muslim and Jewish perspectives on less invasive perinatal and paediatric autopsy by Lewis, Celine, Latif, Zahira, Hill, Melissa, Riddington, Megan, Lakhanpaul, Monica, Arthurs, Owen J, Hutchinson, John C, Chitty, Lyn S, Sebire, Neil J

“…Perinatal and paediatric autopsy rates are at historically low levels with declining uptake due to dislike of the invasiveness of the procedure, and religious…”
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Routine placental histopathology findings from women testing positive for SARS‐CoV‐2 during pregnancy: Retrospective cohort comparative study by Colley, Charlotte S., Hutchinson, J. Ciaran, Whitten, Sara M., Siassakos, Dimitrios, Sebire, Neil J., Hillman, Sara L.

“…Objective To assess the impact of maternal Coronavirus disease 2019 (COVID‐19) infection on placental histopathological findings in an unselected population…”
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Postmortem microfocus computed tomography for early gestation fetuses: a validation study against conventional autopsy by Hutchinson, John C., Kang, Xin, Shelmerdine, Susan Cheng, Segers, Valerie, Lombardi, Claudio M., Cannie, Mieke M., Sebire, Neil J., Jani, Jacques C., Arthurs, Owen J.

“…Perinatal autopsy provides useful clinical information in up to 40% of cases. However, there is a substantial unmet clinical need with regards to postmortem…”
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Optimization of Liver Decellularization Maintains Extracellular Matrix Micro-Architecture and Composition Predisposing to Effective Cell Seeding by Maghsoudlou, Panagiotis, Georgiades, Fanourios, Smith, Holly, Milan, Anna, Shangaris, Panicos, Urbani, Luca, Loukogeorgakis, Stavros P, Lombardi, Benedetta, Mazza, Giuseppe, Hagen, Charlotte, Sebire, Neil J, Turmaine, Mark, Eaton, Simon, Olivo, Alessandro, Godovac-Zimmermann, Jasminka, Pinzani, Massimo, Gissen, Paul, De Coppi, Paolo

“…Hepatic tissue engineering using decellularized scaffolds is a potential therapeutic alternative to conventional transplantation. However, scaffolds are…”
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Making the invisible visible: New perspectives on the intersection of human–environment interactions of clinical teams in intensive care by Visram, Sheena, Potts, Laura, Sebire, Neil J., Rogers, Yvonne, Broughton, Emma, Chigaru, Linda, Nambyiah, Pratheeban

“…Understanding human behaviour is essential to the successful adoption of new technologies, and for the promotion of safer care. This requires capturing the…”
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Early clinical applications for imaging at microscopic detail: microfocus computed tomography (micro-CT) by Hutchinson, J Ciaran, Shelmerdine, Susan C, Simcock, Ian C, Sebire, Neil J, Arthurs, Owen J

“…Microfocus CT (micro-CT) has traditionally been used in industry and preclinical studies, although it may find new applicability in the routine clinical…”
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TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia by Maschietto, Mariana, Williams, Richard D, Chagtai, Tasnim, Popov, Sergey D, Sebire, Neil J, Vujanic, Gordan, Perlman, Elizabeth, Anderson, James R, Grundy, Paul, Dome, Jeffrey S, Pritchard-Jones, Kathy

“…The presence of diffuse anaplasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we…”
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Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction by Spencer, Rebecca, Maksym, Kasia, Hecher, Kurt, Maršál, Karel, Figueras, Francesc, Ambler, Gareth, Whitwell, Harry, Nené, Nuno Rocha, Sebire, Neil J, Hansson, Stefan R, Diemert, Anke, Brodszki, Jana, Gratacós, Eduard, Ginsberg, Yuval, Weissbach, Tal, Peebles, Donald M, Zachary, Ian, Marlow, Neil, Huertas-Ceballos, Angela, David, Anna L

“…BACKGROUNDSevere, early-onset fetal growth restriction (FGR) causes significant fetal and neonatal mortality and morbidity. Predicting the outcome of affected…”
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Intraoperative Needle Tip Tracking with an Integrated Fibre-Optic Ultrasound Sensor by Baker, Christian, Xochicale, Miguel, Lin, Fang-Yu, Mathews, Sunish, Joubert, Francois, Shakir, Dzhoshkun I, Miles, Richard, Mosse, Charles A, Zhao, Tianrui, Liang, Weidong, Kunpalin, Yada, Dromey, Brian, Mistry, Talisa, Sebire, Neil J, Zhang, Edward, Ourselin, Sebastien, Beard, Paul C, David, Anna L, Desjardins, Adrien E, Vercauteren, Tom, Xia, Wenfeng

“…Ultrasound is an essential tool for guidance of many minimally-invasive surgical and interventional procedures, where accurate placement of the interventional…”
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