Search Results - "Sebert, Sylvain"
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Nutritional programming of the metabolic syndrome
Published in Nature reviews. Endocrinology (01-11-2009)“…Early foundations of the metabolic syndrome may be laid as a consequence of changes in dietary supply to the rapidly growing fetus and/or postnatal offspring…”
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2
A bidirectional Mendelian randomisation study to evaluate the relationship between body constitution and hearing loss
Published in Scientific reports (27-10-2023)“…Hearing loss and hearing disorders represent possible mediating pathways in the associations between noise exposures and non-auditory health outcomes. In this…”
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3
The early programming of metabolic health: is epigenetic setting the missing link?
Published in The American journal of clinical nutrition (01-12-2011)“…Adult health is dependent, in part, on maternal nutrition and growth during early life, which may independently affect insulin sensitivity, body composition,…”
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4
Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study
Published in Diabetes (New York, N.Y.) (01-08-2019)“…Liver dysfunction and type 2 diabetes (T2D) are consistently associated. However, it is currently unknown whether liver dysfunction contributes to, results…”
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Maternal and infant prediction of the child BMI trajectories; studies across two generations of Northern Finland birth cohorts
Published in International Journal of Obesity (01-02-2021)“…Background/objective Children BMI is a longitudinal phenotype, developing through interplays between genetic and environmental factors. Whilst childhood…”
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Cognitive Function, Mental Health, and Quality of Life in Siblings of Preterm Born Children: Protocol for a Systematic Review
Published in JMIR research protocols (14-04-2022)“…Children and adults born preterm are at increased risk of cognitive impairments, mental health disorders, and poorer quality of life. Epidemiological studies…”
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The determinants and longitudinal changes in vitamin D status in middle-age: a Northern Finland Birth Cohort 1966 study
Published in European journal of nutrition (01-12-2021)“…Purpose Populations living in the Nordic countries are at high risk for vitamin D (VitD) deficiency or insufficiency. To reduce the risk, nationwide…”
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8
Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies
Published in PLoS genetics (01-12-2020)“…Babies born clinically Small- or Large-for-Gestational-Age (SGA or LGA; sex- and gestational age-adjusted birth weight (BW) <10th or >90th percentile,…”
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9
The association between diabetes and cognitive changes during aging
Published in Scandinavian journal of primary health care (02-07-2020)“…Worldwide, we are observing a rising prevalence of dementia and mild cognitive impairments that often co-occur with the heightened incidence of…”
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10
Vitamin D Status in Women with a History of Infertility and Decreased Fecundability: A Population-Based Study
Published in Nutrients (29-05-2023)“…Infertility and fecundability problems have been linked with lower 25-hydroxyvitamin D (25(OH)D) concentrations, but studies conducted with small, heterogenous…”
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Vitamin D Status and Components of Metabolic Syndrome in Older Subjects from Northern Finland (Latitude 65°North)
Published in Nutrients (30-05-2019)“…Vitamin D deficiency has been linked to the increased risk of several chronic diseases, especially in people living in the Northern Latitudes. The aim of this…”
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12
Exploring the causal effect of maternal pregnancy adiposity on offspring adiposity: Mendelian randomisation using polygenic risk scores
Published in BMC medicine (01-02-2022)“…Greater maternal adiposity before or during pregnancy is associated with greater offspring adiposity throughout childhood, but the extent to which this is due…”
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13
Clinical-Grade Patches as a Medium for Enrichment of Sweat-Extracellular Vesicles and Facilitating Their Metabolic Analysis
Published in International journal of molecular sciences (01-04-2023)“…Cell-secreted extracellular vesicles (EVs), carrying components such as RNA, DNA, proteins, and metabolites, serve as candidates for developing non-invasive…”
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14
Maternal prenatal cholesterol levels predict offspring weight trajectories during childhood in the Norwegian Mother, Father and Child Cohort Study
Published in BMC medicine (06-02-2023)“…Numerous intrauterine factors may affect the offspring's growth during childhood. We aimed to explore if maternal and paternal prenatal lipid, apolipoprotein…”
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Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue
Published in Scientific reports (18-03-2015)“…Common variants of human fat mass- and obesity-associated gene Fto have been linked with higher body mass index, but the biological explanation for the link…”
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Early exposure to social disadvantages and later life body mass index beyond genetic predisposition in three generations of Finnish birth cohorts
Published in BMC public health (18-05-2020)“…The study aimed to explore the association between early life and life-course exposure to social disadvantage and later life body mass index (BMI) accounting…”
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NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects
Published in Human molecular genetics (15-06-2018)Get full text
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Effect of common pregnancy and perinatal complications on offspring metabolic traits across the life course: a multi-cohort study
Published in BMC medicine (18-01-2023)“…Common pregnancy and perinatal complications are associated with offspring cardiometabolic risk factors. These complications may influence multiple metabolic…”
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Genetic correlation and causal relationships between cardio-metabolic traits and lung function impairment
Published in Genome medicine (21-06-2021)“…Associations of low lung function with features of poor cardio-metabolic health have been reported. It is, however, unclear whether these co-morbidities…”
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Vitamin D Levels in Women with Polycystic Ovary Syndrome: A Population-Based Study
Published in Nutrients (19-11-2019)“…Conflicting evidence supports a role for vitamin D in women with reproductive disorders such as polycystic ovary syndrome (PCOS) but studies on large,…”
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