Search Results - "Sebastian Sten"
-
1
A quantitative analysis of cell-specific contributions and the role of anesthetics to the neurovascular coupling
Published in NeuroImage (Orlando, Fla.) (15-07-2020)“…The neurovascular coupling (NVC) connects neuronal activity to hemodynamic responses in the brain. This connection is the basis for the interpretation of…”
Get full text
Journal Article -
2
A quantitative model for human neurovascular coupling with translated mechanisms from animals
Published in PLoS computational biology (01-01-2023)“…Neurons regulate the activity of blood vessels through the neurovascular coupling (NVC). A detailed understanding of the NVC is critical for understanding data…”
Get full text
Journal Article -
3
Mechanistic model for human brain metabolism and its connection to the neurovascular coupling
Published in PLoS computational biology (01-12-2022)“…The neurovascular and neurometabolic couplings (NVC and NMC) connect cerebral activity, blood flow, and metabolism. This interconnection is used in for…”
Get full text
Journal Article -
4
Mechanistic Mathematical Modeling Tests Hypotheses of the Neurovascular Coupling in fMRI
Published in PLoS computational biology (01-06-2016)“…Functional magnetic resonance imaging (fMRI) measures brain activity by detecting the blood-oxygen-level dependent (BOLD) response to neural activity. The BOLD…”
Get full text
Journal Article -
5
Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs)
Published in Clinical pharmacokinetics (01-12-2023)“…Small-interfering ribonucleic acids (siRNAs) with N-acetylgalactosamine (GalNAc) conjugation for improved liver uptake represent an emerging class of drugs…”
Get full text
Journal Article -
6
A quantitative model for human neurovascular coupling with translated mechanisms from animals
Published in PLoS computational biology (01-01-2023)“…Neurons regulate the activity of blood vessels through the neurovascular coupling (NVC). A detailed understanding of the NVC is critical for understanding data…”
Get full text
Journal Article -
7
Mathematical Modeling of Neurovascular Coupling
Published 01-01-2020“…The brain is critically dependent on the continuous supply of oxygen and glucose, which is carried and delivered by blood. When a brain region is activated,…”
Get full text
Dissertation -
8
Neural inhibition can explain negative BOLD responses: A mechanistic modelling and fMRI study
Published in NeuroImage (Orlando, Fla.) (01-09-2017)“…Functional magnetic resonance imaging (fMRI) of hemodynamic changes captured in the blood oxygen level-dependent (BOLD) response contains information of brain…”
Get full text
Journal Article