Search Results - "Sebastian, Manu M."

Streptozotocin-induced hyperglycemia alters the cecal metabolome and exacerbates antibiotic-induced dysbiosis by Wurster, Jenna I., Peterson, Rachel L., Brown, Claire E., Penumutchu, Swathi, Guzior, Douglas V., Neugebauer, Kerri, Sano, William H., Sebastian, Manu M., Quinn, Robert A., Belenky, Peter

“…It is well established in the microbiome field that antibiotic (ATB) use and metabolic disease both impact the structure and function of the gut microbiome…”
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Activation of 4-1BB on Liver Myeloid Cells Triggers Hepatitis via an Interleukin-27-Dependent Pathway by Bartkowiak, Todd, Jaiswal, Ashvin R, Ager, Casey R, Chin, Renee, Chen, Chao-Hsien, Budhani, Pratha, Ai, Midan, Reilley, Matthew J, Sebastian, Manu M, Hong, David S, Curran, Michael A

“…Agonist antibodies targeting the T-cell costimulatory receptor 4-1BB (CD137) are among the most effective immunotherapeutic agents across preclinical cancer…”
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Mouse Models of Overexpression Reveal Distinct Oncogenic Roles for Different Type I Protein Arginine Methyltransferases by Bao, Jianqiang, Di Lorenzo, Alessandra, Lin, Kevin, Lu, Yue, Zhong, Yi, Sebastian, Manu M, Muller, William J, Yang, Yanzhong, Bedford, Mark T

“…Protein arginine methyltransferases (PRMT) are generally not mutated in diseased states, but they are overexpressed in a number of cancers, including breast…”
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PPARD and Interferon Gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice by Zuo, Xiangsheng, Deguchi, Yasunori, Xu, Weiguo, Liu, Yi, Li, Haiyan S., Wei, Daoyan, Tian, Rui, Chen, Weidong, Xu, Min, Yang, Yaying, Gao, Shen, Jaoude, Jonathan C., Liu, Fuyao, Chrieki, Sarah P., Moussalli, Micheline J., Gagea, Mihai, Sebastian, Manu M., Zheng, Xiaofeng, Tan, Dongfeng, Broaddus, Russell, Wang, Jing, Ajami, Nadim J., Swennes, Alton G., Watowich, Stephanie S., Shureiqi, Imad

“…The peroxisome proliferator-activated receptor delta (PPARD) regulates cell metabolism, proliferation, and inflammation and has been associated with gastric…”
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Enhancing oral delivery of plant-derived vesicles for colitis by Liu, Yuan, Ahumada, Adrian Lankenau, Bayraktar, Emine, Schwartz, Paul, Chowdhury, Mamur, Shi, Sixiang, Sebastian, Manu M., Khant, Htet, de Val, Natalia, Bayram, Nazende Nur, Zhang, Guodong, Vu, Thanh Chung, Jie, Zuliang, Jennings, Nicholas B., Rodriguez-Aguayo, Cristian, Swain, Jody, Stur, Elaine, Mangala, Lingegowda S., Wu, Yutuan, Nagaraju, Supriya, Ermias, Brooke, Li, Chun, Lopez-Berestein, Gabriel, Braam, Janet, Sood, Anil K.

“…Plant-derived vesicles (PDVs) are attractive for therapeutic applications, including as potential nanocarriers. However, a concern with oral delivery of PDVs…”
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Society of Toxicologic Pathology Digital Pathology and Image Analysis Special Interest Group Article: Opinion on the Application of Artificial Intelligence and Machine Learning to Digital Toxicologic Pathology by Turner, Oliver C., Aeffner, Famke, Bangari, Dinesh S., High, Wanda, Knight, Brian, Forest, Tom, Cossic, Brieuc, Himmel, Lauren E., Rudmann, Daniel G., Bawa, Bhupinder, Muthuswamy, Anantharaman, Aina, Olulanu H., Edmondson, Elijah F., Saravanan, Chandrassegar, Brown, Danielle L., Sing, Tobias, Sebastian, Manu M.

“…Toxicologic pathology is transitioning from analog to digital methods. This transition seems inevitable due to a host of ongoing social and medical…”
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Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer by Shah, Vrutant V., Duncan, Aundrietta D., Jiang, Shiming, Stratton, Sabrina A., Allton, Kendra L., Yam, Clinton, Jain, Abhinav, Krause, Patrick M., Lu, Yue, Cai, Shirong, Tu, Yizheng, Zhou, Xinhui, Zhang, Xiaomei, Jiang, Yan, Carroll, Christopher L., Kang, Zhijun, Liu, Bin, Shen, Jianjun, Gagea, Mihai, Manu, Sebastian M., Huo, Lei, Gilcrease, Michael, Powell, Reid T., Guo, Lei, Stephan, Clifford, Davies, Peter J., Parker-Thornburg, Jan, Lozano, Guillermina, Behringer, Richard R., Piwnica-Worms, Helen, Chang, Jeffrey T., Moulder, Stacy L., Barton, Michelle Craig

“…Conditional overexpression of histone reader Tri partite m otif containing protein 24 (TRIM24) in mouse mammary epithelia ( Trim24 COE ) drives spontaneous…”
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Rules of engagement: Promoting academic-industry partnership in the era of digital pathology and artificial intelligence by Pantanowitz, Liron, Bui, Marilyn M., Chauhan, Chhavi, ElGabry, Ehab, Hassell, Lewis, Li, Zaibo, Parwani, Anil V., Salama, Mohamed E., Sebastian, Manu M., Tulman, David, Vepa, Suryanarayana, Becich, Michael J.

“…Academic industry partnership (AIP) represents an important alliance between academic researchers and industry that helps translate technology and complete the…”
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Suspected systemic calcinosis and calciphylaxis in 5 horses by Tan, Jean-Yin, Valberg, Stephanie J, Sebastian, Manu M, Davis, Gordon D, Kelly, Jenny R, Goehring, Lutz S, Harland, Malte M, Kuebelbeck, K Leann, Waldridge, Bryan M, Newton, Joseph C, Reimer, Johanna M

“…Five horses were presented with signs of myopathy along with systemic malaise, hyperfibrinogenemia, hyperphosphatemia, and an elevated calcium phosphorus…”
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STILLBORN INFANT WITH CALCIFIED CHORIONIC EPITHELIUM, CORNEAL SCARRING, AND PERICARDITIS by Brendon, Robert W., Sebastian, Manu M.

“…This autopsy of a stillborn term infant revealed a constellation of unusual features including calcification of the chorion membrane and portions of the…”
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PL-315: A comparison of sleeve gastrectomy and duodenal-jejunal bypass on glucose homeostasis in a rodent model of obesity and type 2 diabetes mellitus by Inabnet, William, MD, Lifante, Jean-Christophe, MD, Milone, Luca, MD, Korner, Judith, MD, PhD, Kopsombut, Gift, Sebastian, Manu M., DVM, MS, PhD

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Microbiologic and pathologic findings in an epidemic of equine pericarditis by Bolin, DC, Donahue, JM, Vickers, ML, Harrison, L, Sells, S, Giles, RC, Hong, CB, Poonacha, KB, Roberts, J, Sebastian, MM, Swerczek, TW, Tramontin, R, Williams, NM

“…Livestock Disease Diagnostic Center, College of Agriculture, University of Kentucky, Lexington, KY 40511-4125, USA. During the spring and summer of 2001 and in…”
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Equine Abortion and Premature Birth Associated with Cellulosimicrobium Cellulans Infection by Bolin, David C, Donahue, James M, Vickers, Mary L, Giles, Ralph C, Harrison, Lenn, Jackson, Carney, Poonacha, K.B, Roberts, John F, Sebastian, Manu M, Sells, Steve F, Tramontin, Robert, Williams, Neil M

“…During the 2002 and 2003 foaling seasons, Cellulosimicrobium (Cellumonas) cellulans (formerly Oerskovia xanthineolytica) was the principal microorganism…”
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Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group by Amgad, Mohamed, Stovgaard, Elisabeth Specht, Balslev, Eva, Thagaard, Jeppe, Chen, Weijie, Dudgeon, Sarah, Sharma, Ashish, Kerner, Jennifer K., Denkert, Carsten, Yuan, Yinyin, AbdulJabbar, Khalid, Wienert, Stephan, Savas, Peter, Voorwerk, Leonie, Beck, Andrew H., Madabhushi, Anant, Hartman, Johan, Sebastian, Manu M., Horlings, Hugo M., Hudeček, Jan, Ciompi, Francesco, Moore, David A., Singh, Rajendra, Roblin, Elvire, Balancin, Marcelo Luiz, Mathieu, Marie-Christine, Lennerz, Jochen K., Kirtani, Pawan, Chen, I-Chun, Braybrooke, Jeremy P., Pruneri, Giancarlo, Demaria, Sandra, Adams, Sylvia, Schnitt, Stuart J., Lakhani, Sunil R., Rojo, Federico, Comerma, Laura, Badve, Sunil S., Khojasteh, Mehrnoush, Symmans, W. Fraser, Sotiriou, Christos, Gonzalez-Ericsson, Paula, Pogue-Geile, Katherine L., Kim, Rim S., Rimm, David L., Viale, Giuseppe, Hewitt, Stephen M., Bartlett, John M. S., Penault-Llorca, Frédérique, Goel, Shom, Lien, Huang-Chun, Loibl, Sibylle, Kos, Zuzana, Loi, Sherene, Hanna, Matthew G., Michiels, Stefan, Kok, Marleen, Nielsen, Torsten O., Lazar, Alexander J., Bago-Horvath, Zsuzsanna, Kooreman, Loes F. S., van der Laak, Jeroen A. W. M., Saltz, Joel, Gallas, Brandon D., Kurkure, Uday, Barnes, Michael, Salgado, Roberto, Cooper, Lee A. D.

“…Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral part of the prognostic workflow in triple-negative (TNBC) and…”
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The Toxicokinetics of Cyanide and Mandelonitrile in the Horse and Their Relevance to the Mare Reproductive Loss Syndrome by Dirikolu, Levent, Hughes, Charlie, Harkins, Dan, Boyles, Jeff, Bosken, Jeff, Lehner, Fritz, Troppmann, Amy, McDowell, Karen, Tobin, Thomas, Sebastian, Manu M., Harrison, Lenn, Crutchfield, James, Baskin, Steven I., Fitzgerald, Terrence D.

“…The epidemiological association between black cherry trees and mare reproductive loss syndrome has focused attention on cyanide and environmental cyanogens…”
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Abstract 2720: Enhancing oral delivery of plant-derived vesicles by Liu, Yuan, Lankenau-Ahumada, Adrian, Bayraktar, Emine, Schwartz, Paul, Chowdhury, Mamur, Shi, Sixiang, Sebastian, Manu M., Khant, Htet, De Val, Natalia, Jie, Zuliang, Jennings, Nicholas B., Rodriguez-Aguayo, Cristian, Swain, Jody, Stur, Elaine, Mangala, Lingegowda S., Wu, Yutuan, Nagaraju, Supriya, Erimas, Brooke, Li, Chun, Lopez-Berestein, Gabriel, Braam, Janet, Sood, Anil K.

“…Abstract Plant-derived vesicles (PDVs) were attractive for therapeutic applications, including as potential nanocarriers. However, a concern with oral delivery…”
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Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group by Amgad, Mohamed, Stovgaard, Elisabeth Specht, Balslev, Eva, Thagaard, Jeppe, Chen, Weijie, Dudgeon, Sarah, Sharma, Ashish, Kerner, Jennifer K, Denkert, Carsten, Yuan, Yinyin, AbdulJabbar, Khalid, Wienert, Stephan, Savas, Peter, Voorwerk, Leonie, Beck, Andrew H, Madabhushi, Anant, Hartman, Johan, Sebastian, Manu M, Horlings, Hugo M, Hudeček, Jan, Ciompi, Francesco, Moore, David A, Singh, Rajendra, Roblin, Elvire, Balancin, Marcelo Luiz, Mathieu, Marie-Christine, Lennerz, Jochen K, Kirtani, Pawan, Chen, I-Chun, Braybrooke, Jeremy P, Pruneri, Giancarlo, Demaria, Sandra, Adams, Sylvia, Schnitt, Stuart J, Lakhani, Sunil R, Rojo, Federico, Comerma, Laura, Badve, Sunil S, Khojasteh, Mehrnoush, Symmans, W Fraser, Sotiriou, Christos, Gonzalez-Ericsson, Paula, Pogue-Geile, Katherine L, Kim, Rim S, Rimm, David L, Viale, Giuseppe, Hewitt, Stephen M, Bartlett, John M S, Penault-Llorca, Frédérique, Goel, Shom, Lien, Huang-Chun, Loibl, Sibylle, Kos, Zuzana, Loi, Sherene, Hanna, Matthew G, Michiels, Stefan, Kok, Marleen, Nielsen, Torsten O, Lazar, Alexander J, Bago-Horvath, Zsuzsanna, Kooreman, Loes F S, van der Laak, Jeroen A W M, Saltz, Joel, Gallas, Brandon D, Kurkure, Uday, Barnes, Michael, Salgado, Roberto, Cooper, Lee A D

“…Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral part of the prognostic workflow in triple-negative (TNBC) and…”
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The utility of [11 C] dihydrotetrabenazine positron emission tomography scanning in assessing β-cell performance after sleeve gastrectomy and duodenal-jejunal bypass by Inabnet, William B., MD, Milone, Luca, MD, Harris, Paul, MD, Durak, Evren, MD, Freeby, Matthew J., MD, Ahmed, Leaque, MD, Sebastian, Manu, MD, Lifante, Jean-Christophe, MD, Bessler, Marc, MD, Korner, Judith, MD, PhD

“…Background The aim of this study was to evaluate the effect of sleeve gastrectomy (SG) and duodenal-jejunal bypass (DJB) on glucose homeostasis and to evaluate…”
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The mare reproductive loss syndrome and the eastern tent caterpillar: a toxicokinetic/statistical analysis with clinical, epidemiologic, and mechanistic implications by Sebastian, Manu, Gantz, Marie G, Tobin, Thomas, Harkins, J Daniel, Bosken, Jeffrey M, Hughes, Charlie, Harrison, Lenn R, Bernard, William V, Richter, Dana L, Fitzgerald, Terrence D

“…During 2001, central Kentucky experienced acute transient epidemics of early and late fetal losses, pericarditis, and unilateral endophthalmitis, collectively…”
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