Search Results - "Sebald, W"
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Enforced covalent trimerization increases the activity of the TNF ligand family members TRAIL and CD95L
Published in Cell death and differentiation (01-12-2007)“…Variants of human TRAIL (hTRAIL) and human CD95L (hCD95L), encompassing the TNF homology domain (THD), interact with the corresponding receptors and stimulate…”
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IL-4 Enhances Proliferation and Mediator Release in Mature Human Mast Cells
Published in Proceedings of the National Academy of Sciences - PNAS (06-07-1999)“…Tissue mast cells (MC) are recognized as key effector cells of immediate-type allergic reactions releasing inflammatory mediators and cytokines on stimulation…”
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Sustained Release Carriers Used to Delivery Bone Morphogenetic Proteins in the Bone Healing Process
Published in Anatomia, histologia, embryologia (01-06-2008)“…Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor β superfamily, especially BMP-2, induce bone…”
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Dual role of the IL-12/IFN-gamma axis in the development of autoimmune myocarditis: induction by IL-12 and protection by IFN-gamma
Published in The Journal of immunology (1950) (01-11-2001)“…IL-12 and IFN-gamma positively regulate each other and type 1 inflammatory responses, which are believed to cause tissue damage in autoimmune diseases. We…”
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Time kinetics of bone defect healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics
Published in European cells & materials (11-02-2011)“…This study reports that treatment of osseous defects with different growth factors initiates distinct rates of repair. We developed a new method for monitoring…”
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Sebald’s dissertation, University of Fribourg
Published in Journal of European studies (01-12-2011)“…Sebald argues that all the aesthetic and moral flaws of Carl Sternheim’s writings come from the failure of his attempt, as a Jew, to assimilate into Wilhelmine…”
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The carved wooden angels of East Anglia: Travelogue 1974
Published in Journal of European studies (01-12-2011)“…In 1974 W. G. Sebald wrote a travelogue for the educated German reader, proposing a circular tour of discovery around East Anglia. He recommends places to…”
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Radiation-Induced Suppression of the Bmp2 Signal Transduction Pathway in the Pluripotent Mesenchymal Cell Line C2C12: An In Vitro Model for Prevention of Heterotopic Ossification by Radiotherapy
Published in Radiation research (01-03-2003)“…Pohl, F., Hassel, S., Nohe, A., Flentje, M., Knaus, P., Sebald, W. and Koelbl, O. Radiation-Induced Suppression of the Bmp2 Signal Transduction Pathway in the…”
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A single administration of interleukin-4 antagonistic mutant DNA inhibits allergic airway inflammation in a mouse model of asthma
Published in Gene therapy (01-12-2003)“…Interleukin 4 (IL-4) is essential for the switching of B cells to IgE antibody production and for the maturation of T helper (Th) cells toward the Th2…”
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The Crystal Structure of the BMP-2: BMPR-IA Complex and the Generation of BMP-2 Antagonists
Published in Journal of bone and joint surgery. American volume (01-01-2001)“…BackgroundBone morphogenetic proteins (BMPs) and growth and differentiation factors (GDFs) belong to the large transforming growth factor-β (TGF-β) superfamily…”
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The impact of the route and frequency of antigen exposure on the IgE response in allergy
Published in International archives of allergy and immunology (01-04-2001)“…Knowledge of the factors which control IgE production is essential in order to understand the pathogenesis of immediate hypersensitivity reactions. We have…”
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Inductive properties of recombinant human BMP-2 produced in a bacterial expression system
Published in International journal of oral and maxillofacial surgery (01-08-1998)“…Recombinant human BMP-2, produced in E. coli, refolded and concentrated to a purity of more than 98%, has been demonstrated to be biologically active. In…”
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Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT- type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation
Published in The American journal of pathology (01-05-1997)“…To investigate the mechanisms of T cell dependence underlying the development of extranodal mucosa-associated lymphoid tissue (MALT)-type B cell lymphomas, the…”
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Conversion of human interleukin‐4 into a high affinity antagonist by a single amino acid replacement
Published in The EMBO journal (01-09-1992)“…Interleukin‐4 (IL‐4) represents a prototypic lymphokine (for a recent review see Paul, 1991). It promotes differentiation of B‐cells and the proliferation of…”
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Connective tissue growth factor does not affect transforming growth factor-beta 1-induced Smad3 phosphorylation and T lymphocyte proliferation inhibition
Published in International archives of allergy and immunology (01-01-2008)“…Transforming growth factor-beta 1 (TGF-beta(1)) is a key regulator of immune tolerance. TGF-beta(1) controls T lymphocyte activation and is involved in the…”
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Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation
Published in The EMBO journal (15-12-1993)“…Interleukin 4 (IL‐4) exerts a decisive role in the coordination of protective immune responses against parasites, particularly helminths. A disregulation of…”
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Comparison of the osteogenic activity of bone morphogenetic protein (BMP) mutants
Published in Mund-, Kiefer- und Gesichtschirurgie : MKG (01-11-2005)“…Modification of the heparin binding site by alteration of the amino acid sequence of bone morphogenetic protein-2 (BMP-2) results in a change in the local…”
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Radiation-induced impairment of bone healing can be overcome by recombinant human bone morphogenetic protein-2
Published in The Journal of craniofacial surgery (01-03-1998)“…Radiotherapy of head and neck tumors very often results in impaired healing of craniomaxillofacial bones in the vicinity. Management of radionecrosis of bones…”
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The triose phosphate‐3‐phosphoglycerate‐phosphate translocator from spinach chloroplasts: nucleotide sequence of a full‐length cDNA clone and import of the in vitro synthesized precursor protein into chloroplasts
Published in The EMBO journal (01-01-1989)“…The nucleotide sequence of several cDNA clones coding for the phosphate translocator from spinach chloroplasts has been determined. The cDNA clones were…”
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