Search Results - "Seay, Ulrike"
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Comparison of the Effects of Carbon Ion and Photon Irradiation on the Angiogenic Response in Human Lung Adenocarcinoma Cells
Published in International journal of radiation oncology, biology, physics (01-08-2011)“…Purpose Radiotherapy resistance is a commonly encountered problem in cancer treatment. In this regard, stabilization of endothelial cells and release of…”
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Caveolin-1 Facilitates Mechanosensitive Protein Kinase B (Akt) Signaling In Vitro and In Vivo
Published in Circulation research (01-04-2005)“…Mechanotransduction represents an integral part of vascular homeostasis and contributes to vascular lesion formation. Previously, we demonstrated a…”
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Cell Cycle Protein Expression in Vascular Smooth Muscle Cells In Vitro and In Vivo Is Regulated Through Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin
Published in Arteriosclerosis, thrombosis, and vascular biology (01-07-2001)“…Cell cycle progression represents a key event in vascular proliferative diseases, one that depends on an increased rate of protein synthesis. An increase in…”
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Inhibition of Matrix Deposition: A New Strategy for Prevention of Restenosis After Balloon Angioplasty
Published in Journal of cardiovascular pharmacology (01-02-2010)“…Restenosis after balloon angioplasty or stent placement is characterized by local accumulation of mainly vascular smooth muscle cells and the synthesis of…”
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Carbon ion radiotherapy of human lung cancer attenuates HIF‐1 signaling and acts with considerably enhanced therapeutic efficiency
Published in The FASEB journal (01-03-2014)“…Carbon ion irradiation is an emerging therapeutic option for various tumor entities. Radiation resistance of solid tumors toward photon irradiation is caused…”
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Information on new drugs at market entry: retrospective analysis of health technology assessment reports versus regulatory reports, journal publications, and registry reports
Published in BMJ (Online) (26-02-2015)“…Background When a new drug becomes available, patients and doctors require information on its benefits and harms. In 2011, Germany introduced the early benefit…”
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Transforming growth factor-beta-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent
Published in The Journal of pharmacology and experimental therapeutics (01-12-2005)“…Vascular smooth muscle cells (VSMCs) constitute the major cellular component of the vessel tunica media. VSMC proliferation is a key feature in developing…”
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Hypoxia‐driven proliferation of human pulmonary artery fibroblasts: cross‐talk between HIF‐1α and an autocrine angiotensin system
Published in The FASEB journal (01-05-2005)“…ABSTRACT Pulmonary artery adventitial fibroblasts (FBPA) may play a central role in lung vascular remodeling under conditions of hypoxia and inflammation, the…”
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Spatiotemporal Expression of flk-1 in Pulmonary Epithelial Cells during Lung Development
Published in American journal of respiratory cell and molecular biology (01-08-2008)“…Vascular endothelial growth factor-A (VEGF-A) responsive effects mediated via the receptors fetal liver kinase-1 (flk-1) and fms-like tyrosine kinase (flt-1),…”
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10
Calpain counteracts mechanosensitive apoptosis of vascular smooth muscle cells in vitro and in vivo
Published in The FASEB journal (01-02-2008)“…Mechanical forces contribute to vascular remodeling processes. Elevated mechanical stress causes apoptosis of vascular smooth muscle cells (VSMCs) within the…”
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Impact of the epithelial HIF 2 alpha system on lung development
Published in The FASEB journal (01-03-2008)“…Abstract only During lung development endothelial Flk‐1 is a key regulator of blood vessel formation and regulated by HIF 2‐alpha. Hif 2‐alpha is highly…”
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Mechanosensitive p27 Kip1 Regulation and Cell Cycle Entry in Vascular Smooth Muscle Cells
Published in Circulation (New York, N.Y.) (05-08-2003)“…Background— Cyclic stretch plays an important role in the homeostasis of vessel structure. Increased forces might, however, contribute to remodeling processes,…”
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Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells
Published in Circulation (New York, N.Y.) (05-08-2003)“…Cyclic stretch plays an important role in the homeostasis of vessel structure. Increased forces might, however, contribute to remodeling processes, resulting…”
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Protective effect of 3-deazaadenosine in a rat model of lipopolysaccharide-induced myocardial dysfunction
Published in Shock (Augusta, Ga.) (01-03-2003)“…Severe sepsis is accompanied by a profound depression of myocardial contractility. Leukocyte adhesion with subsequent local excess nitric oxide and reactive…”
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Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1alpha and an autocrine angiotensin system
Published in The FASEB journal (01-05-2005)“…Pulmonary artery adventitial fibroblasts (FBPA) may play a central role in lung vascular remodeling under conditions of hypoxia and inflammation, the result…”
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Expression of the nerve growth factor receptor c-TRK in human myeloid leukaemia cells
Published in British journal of haematology (01-10-1996)“…Nerve growth factor (NGF) is of major importance for the survival, development and maintenance of peripheral sympathetic and central neuronal tissue. Most of…”
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