Search Results - "Searson, David"

Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test by Hinestrosa, Juan Pablo, Kurzrock, Razelle, Lewis, Jean M., Schork, Nicholas J., Schroeder, Gregor, Kamat, Ashish M., Lowy, Andrew M., Eskander, Ramez N., Perrera, Orlando, Searson, David, Rastegar, Kiarash, Hughes, Jake R., Ortiz, Victor, Clark, Iryna, Balcer, Heath I., Arakelyan, Larry, Turner, Robert, Billings, Paul R., Adler, Mark J., Lippman, Scott M., Krishnan, Rajaram

“…Background Detecting cancer at early stages significantly increases patient survival rates. Because lethal solid tumors often produce few symptoms before…”
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Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform by Hinestrosa, Juan Pablo, Searson, David J., Lewis, Jean M., Kinana, Alfred, Perrera, Orlando, Dobrovolskaia, Irina, Tran, Kevin, Turner, Robert, Balcer, Heath I., Clark, Iryna, Bodkin, David, Hoon, Dave S. B., Krishnan, Rajaram

“…The power of personalized medicine is based on a deep understanding of cellular and molecular processes underlying disease pathogenesis. Accurately…”
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Abstract 2850: Characterization of circulating extracellular vesicles isolated from plasma of cancer subjects using novel AC electrokinetics platform by Krishnan, Rajaram, Lewis, Jean, Searson, David, Perrera, Orlando, Kinana, Alfred, Balcer, Heath, Clark, Iryna, Hinestrosa, Juan Pablo

“…Abstract Introduction: Extracellular vesicles (EVs) contain protein and nucleic cargo that has been shown to be reflective of physiological and pathological…”
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Abstract 3978: Direct analysis of exosome-bound proteins and nucleic acids using the ExoVerita™ Flex platform by Lewis, Jean M., Searson, David, Kinana, Alfred, Balcer, Heath, Thompson, Debrah, Bodkin, David, Hinestrosa, Juan P., Krishnan, Rajaram

“…Abstract Exosomes carry signals between cells and may influence cancer development, metastasis, and drug resistance. Unfortunately, current tools for exosome…”
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Development of extracellular vesicles-based classifier for detection of early-stage bladder, ovarian, and pancreatic cancer by Hinestrosa, Juan Pablo, Kurzrock, Razelle, Lewis, Jean, Schork, Nick, Kamat, Ashish M., Lowy, Andrew M., Eskander, Ramez Nassef, Perrera, Orlando, Searson, David, Clark, Iryna, Balcer, Heath, Adler, Mark J., Lippman, Scott Michael, Krishnan, Rajaram

“…Abstract only 3048 Background: Many cancers are lethal because they present with metastatic disease. Because localized/resectable tumors produce vague…”
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Abstract LB-174: Novel AC electrokinetic platform for rapid isolation and characterization of extracellular vesicles from NSCLC patients by Krishnan, Rajaram, Hinestrosa, Juan P., Searson, David, Turner, Robert, Kovelman, Robert, Balcer, Heath, Madsen, James, Bodkin, David

“…Abstract We have developed a novel Alternating Current Electrokinetics (ACE) platform to isolate macromolecules such as circulating cell-free DNA (ccfDNA) and…”
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Abstract 3666: Diagnostic application of novel ACE technology: Treatment response monitoring via quantification of cell-free DNA (cfDNA) in plasma from late-stage cancer patients by Kovelman, Robert, Hinestrosa, Juan Pablo, Ye, Delia, Desmond, Patrick, Nguyen, Michelle, Turner, Robert, Searson, David, Uswatta, Suren, Madsen, James, Bodkin, David, Bazhenova, Lyudmila, Bahador, Afshin, Krishnan, Rajaram

“…Abstract We have developed a novel microfluidic technology that makes use of Alternating Current Electrokinetics (ACE) to isolate macromolecules such as…”
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Abstract 5082: Proteomic analysis of extracellular vesicles from oncology donor samples purified using an alternating current electrokinetic microelectrode chip by Hinestrosa, Juan P., Lewis, Jean M., Searson, David J., Balcer, Heath I., Gonzalez, David J., Krishnan, Rajaram

“…Abstract In this study, we evaluated the ability to detect novel proteins on extracellular vesicles (EVs) following isolation using an alternating current…”
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Novel AC electrokinetic platform for rapid isolation and characterization of extracellular vesicles from NSCLC patients by Hinestrosa, Juan P, Searson, David, Ye, Delia, Kovelman, Robert, Madsen, James, Turner, Robert, Bodkin, David, Krishnan, Rajaram

“…Background: Extracellular vesicles (EVs) contain proteomic and genomic information that can be used for cancer diagnosis and treatment response monitoring…”
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