Search Results - "Sears, Karen"

Limb development: a paradigm of gene regulation by Petit, Florence, Sears, Karen E., Ahituv, Nadav

“…Key Points The limb is widely used as a model in developmental biology. Although the signalling pathways involved in limb development are largely conserved,…”
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Improving cultural competence education: the utility of an intersectional framework by Powell Sears, Karen

“…Medical Education 2012: 46:545–551 Context  Most US medical schools have instituted cultural competence education in the undergraduate curriculum. This…”
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Limb development, evolution, and regeneration and repair: Part two by Gros, Jérôme, Davey, Megan, Sears, Karen E.

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Limb development, evolution, and regeneration & repair: Part 1 by Sears, Karen E., Gros, Jerome, Davey, Megan

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The Role of Core and Variable Gene Regulatory Network Modules in Tooth Development and Evolution by Sadier, Alexa, Santana, Sharlene E, Sears, Karen E

“…Synopsis Among the developmental processes that have been proposed to influence the direction of evolution, the modular organization of developmental gene…”
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Unraveling the heritage of lost traits by Sadier, Alexa, Sears, Karen E., Womack, Molly

“…We synthesize ontogenetic work spanning the past century that show evolutionarily lost structures are rarely entirely absent from earlier developmental stages…”
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Expanding the Evo-Devo Toolkit: Generation of 3D mammary tissue from diverse mammals by Kim, Hahyung Y, Sinha, Ishani, Sears, Karen E, Kuperwasser, Charlotte, Rauner, Gat

“…The varying pathways of mammary gland development across species and evolutionary history are underexplored, largely due to a lack of model systems. Recent…”
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Developmental influence on evolutionary rates and the origin of placental mammal tooth complexity by Couzens, Aidan M. C., Sears, Karen E., Rücklin, Martin

“…Development has often been viewed as a constraining force on morphological adaptation, but its precise influence, especially on evolutionary rates, is poorly…”
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Pedomorphosis in the ancestry of marsupial mammals by White, Heather E., Tucker, Abigail S., Fernandez, Vincent, Portela Miguez, Roberto, Hautier, Lionel, Herrel, Anthony, Urban, Daniel J., Sears, Karen E., Goswami, Anjali

“…Within mammals, different reproductive strategies (e.g., egg laying, live birth of extremely underdeveloped young, and live birth of well-developed young) have…”
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Differences in the Timing of Prechondrogenic Limb Development in Mammals: The Marsupial-Placental Dichotomy Resolved by Sears, Karen E.

“…In contrast to placentals, marsupials are born with forelimbs that are greatly developmentally advanced relative to their hind limbs. Despite significant…”
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Patterning and post-patterning modes of evolutionary digit loss in mammals by Cooper, Kimberly L., Sears, Karen E., Uygur, Aysu, Maier, Jennifer, Baczkowski, Karl-Stephan, Brosnahan, Margaret, Antczak, Doug, Skidmore, Julian A., Tabin, Clifford J.

“…A reduction in the number of digits has evolved many times in tetrapods, particularly in cursorial mammals that travel over deserts and plains, yet the…”
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Bat teeth illuminate the diversification of mammalian tooth classes by Sadier, Alexa, Anthwal, Neal, Krause, Andrew L., Dessalles, Renaud, Lake, Michael, Bentolila, Laurent A., Haase, Robert, Nieves, Natalie A., Santana, Sharlene E., Sears, Karen E.

“…Tooth classes are an innovation that has contributed to the evolutionary success of mammals. However, our understanding of the mechanisms by which tooth…”
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Non-model systems in mammalian forelimb evo-devo by Howenstine, Aidan O, Sadier, Alexa, Anthwal, Neal, Lau, Clive LF, Sears, Karen E

“…Mammal forelimbs are highly diverse, ranging from the elongated wing of a bat to the stout limb of the mole. The mammal forelimb has been a long-standing…”
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Uncovering developmental diversity in the field by Brown, Federico D, Ishengoma, Edson, Mayer, Georg, Pabón-Mora, Natalia, Santos, M Emília, Sears, Karen E, de Sena Oliveira, Ivo

“…Many developmental biologists seldom leave the lab for research, relying instead on establishing colonies of traditional and emerging model systems. However,…”
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Incomplete lineage sorting and phenotypic evolution in marsupials by Feng, Shaohong, Bai, Ming, Rivas-González, Iker, Li, Cai, Liu, Shiping, Tong, Yijie, Yang, Haidong, Chen, Guangji, Xie, Duo, Sears, Karen E., Franco, Lida M., Gaitan-Espitia, Juan Diego, Nespolo, Roberto F., Johnson, Warren E., Yang, Huanming, Brandies, Parice A., Hogg, Carolyn J., Belov, Katherine, Renfree, Marilyn B., Helgen, Kristofer M., Boomsma, Jacobus J., Schierup, Mikkel Heide, Zhang, Guojie

“…Incomplete lineage sorting (ILS) makes ancestral genetic polymorphisms persist during rapid speciation events, inducing incongruences between gene trees and…”
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Bat Dentitions: A Model System for Studies at The Interface of Development, Biomechanics, and Evolution by Santana, Sharlene E, Grossnickle, David M, Sadier, Alexa, Patterson, Edward, Sears, Karen E

“…The evolution of complex dentitions was a major innovation in mammals that facilitated the expansion into new dietary niches that imposed selection for tight…”
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On the serial homology of the pectoral and pelvic girdles of tetrapods by Sears, Karen E., Capellini, Terence D., Diogo, Rui

“…While fore- and hindlimbs are commonly assumed to be serially homologous, the serial homology of the pectoral and pelvic girdles is more ambiguous. We…”
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The Impact of Different Types of Intimate Partner Violence on the Mental and Physical Health of Women in Different Ethnic Groups by Lacey, Krim K., McPherson, Melnee Dilworth, Samuel, Preethy S., Powell Sears, Karen, Head, Doreen

“…Intimate partner violence, including threats, stalking, emotional, physical, and sexual assault by a spouse or partner, has significant influences on the…”
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Embryonic evidence uncovers convergent origins of laryngeal echolocation in bats by Nojiri, Taro, Wilson, Laura A.B., López-Aguirre, Camilo, Tu, Vuong Tan, Kuratani, Shigeru, Ito, Kai, Higashiyama, Hiroki, Son, Nguyen Truong, Fukui, Dai, Sadier, Alexa, Sears, Karen E., Endo, Hideki, Kamihori, Satoshi, Koyabu, Daisuke

“…Bats are the second-most speciose group of mammals, comprising 20% of species diversity today. Their global explosion, representing one of the greatest…”
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A new developmental mechanism for the separation of the mammalian middle ear ossicles from the jaw by Urban, Daniel J., Anthwal, Neal, Luo, Zhe-Xi, Maier, Jennifer A., Sadier, Alexa, Tucker, Abigail S., Sears, Karen E.

“…Multiple mammalian lineages independently evolved a definitive mammalian middle ear (DMME) through breakdown of Meckel's cartilage (MC). However, the cellular…”
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