Ceramide and Cerebroside from the Stem Bark of Ficus mucuso (Moraceae)

Ceramide and Cerebroside from the Stem Bark of Ficus mucuso (Moraceae)

Two new sphingolipids mucusamide (1) and mucusoside (2) have been isolated from methanol soluble part of the stem bark of Ficus mucuso WELW., together with fifteen known secondary metabolites including cellobiosylsterol (3), β-sitosterol (4), stigmasterol (5), β-sitosterol 3-O-β-D-glucopyranoside (6...

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Bibliographic Details
Published in:Chemical & Pharmaceutical Bulletin Vol. 58; no. 12; pp. 1661 - 1665
Main Authors: Jean Jules Kezetas BANKEUa, e, Sufyan Awad Alkarim MUSTAFAb, Anar Sahib GOJAYEVc, Bruno Djakou LENTAd, Diderot TCHAMO NOUNGOUEa, Silvere Augustin NGOUELAa, Khalid ASAADb, Mohammed Iqbal CHOUDHARYe, Sean PRIGGEf, Akif Alekper GULIYEVc, Augustin Ephrem NKENGFACKa, Etienne TSAMOa, Muhammad SHAIQ ALIe
Format: Journal Article
Language:Japanese
Published: Pharmaceutical Society of Japan 2010
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Summary:Two new sphingolipids mucusamide (1) and mucusoside (2) have been isolated from methanol soluble part of the stem bark of Ficus mucuso WELW., together with fifteen known secondary metabolites including cellobiosylsterol (3), β-sitosterol (4), stigmasterol (5), β-sitosterol 3-O-β-D-glucopyranoside (6), lupeol acetate (7), ursolic acid (8), procatechuic acid (9), 2-methyl-5,7-dihydroxychromone 8-C-β-D-glucoside (10), apigenin (11), (-)-epicatechin (12), (+)-catechin (13), N-benzoyl-L-phenylalanilol (14), α-acetylamino-phenylpropyl α-benzoylaminophenylpropionate (15), asperphenamate (16) and bejaminamide (17). Structures of compounds 1 and 2 were elucidated by spectroscopic analysis and chemical methods. Ficus is a genus of the family Moraceae that comprises about 150 species distributed worldwide1). Most of the members of the family are very high trees, shrubs and rarely herbs often with milky juice1). A number of Ficus species are used as food and medicines in Traditional Chinese Medicine (TCM). Their uses, however, originated and are most widely found in the Middle East2). Ficus species are widely used in traditional medicine in Cameroon too.
ISSN:0009-2363