Search Results - "Seal, Sudeshna"
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1
Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
Published in PLoS neglected tropical diseases (01-05-2019)“…Toll-like receptors (TLRs) are sentinel receptors of the innate immune system. TLR4 detects bacterial lipopolysaccharide (LPS) and TLR5 detects bacterial…”
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Journal Article -
2
Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide
Published in PloS one (26-11-2013)“…B. pseudomallei is a gram-negative bacterium that causes the tropical infection melioidosis. In northeast Thailand, mortality from melioidosis approaches 40%…”
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Journal Article -
3
microRNAs regulate human embryonic stem cell division
Published in Cell cycle (Georgetown, Tex.) (15-11-2009)“…RNA interference-mediated suppression of DICER and DROSHA in human embryonic stem cells (hESCs) attenuates cell proliferation, supporting a role for an intact…”
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Journal Article -
4
Differential Effects of Bexarotene on Intrinsic and Extrinsic Pathways in TRAIL-Induced Apoptosis in Myeloid Leukemia Cell Lines
Published in Blood (16-11-2006)“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an attractive candidate for cancer therapy since it induces apoptosis preferentially in…”
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Journal Article -
5
Neutrophil Elastase Catalytic Activity Regulates Granulopoiesis
Published in Blood (02-11-2023)“…Heterozygous, autosomal dominantly inherited mutations in the gene, ELANE, encoding the neutrophil granule serine protease, neutrophil elastase, are the cause…”
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Journal Article -
6
Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to Burkholderia pseudomallei , a lung-tropic pathogen
Published in Infection and immunity (07-05-2024)“…Melioidosis is an emerging tropical infection caused by inhalation, inoculation, or ingestion of the flagellated, facultatively intracellular pathogen . The…”
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Journal Article -
7
TLR4 genetic variation is associated with inflammatory responses in Gram-positive sepsis
Published in Clinical microbiology and infection (01-01-2017)“…To identify important pathogen recognition receptor (PRR) pathways regulating innate immune responses and outcome in Staphylococcus aureus sepsis. We analysed…”
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Journal Article -
8
NF-κB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)
Published in Blood (01-12-2005)“…Tumor necrosis factor (TNF)-α, a potent stimulus of nuclear factor-κB (NF-κB), is up-regulated in myelodysplastic syndrome (MDS). Here, we show that bone…”
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Journal Article -
9
Differential responses of FLIPLong and FLIPShort -overexpressing human myeloid leukemia cells to TNF-α and TRAIL-initiated apoptotic signals
Published in Experimental hematology (01-12-2008)“…Objective Clonal marrow cells from patients with early myelodysplastic syndrome (MDS) undergo apoptosis in response to tumor necrosis factor (TNF)−related…”
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Journal Article -
10
Differential responses of FLIP Long and FLIP Short-overexpressing human myeloid leukemia cells to TNF-α and TRAIL-initiated apoptotic signals
Published in Experimental hematology (2008)“…Clonal marrow cells from patients with early myelodysplastic syndrome (MDS) undergo apoptosis in response to tumor necrosis factor (TNF)−related…”
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Journal Article -
11
NF-kappaB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)
Published in Blood (01-12-2005)“…Tumor necrosis factor (TNF)-alpha, a potent stimulus of nuclear factor-kappaB (NF-kappaB), is up-regulated in myelodysplastic syndrome (MDS). Here, we show…”
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Journal Article -
12
Survey of Innate Immune Responses to Burkholderia pseudomallei in Human Blood Identifies a Central Role for Lipopolysaccharide: e81617
Published in PloS one (01-11-2013)“…B. pseudomallei is a gram-negative bacterium that causes the tropical infection melioidosis. In northeast Thailand, mortality from melioidosis approaches 40%…”
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Journal Article -
13
FLIPLong(L) and FLIPShort(S) Overexpression in the Human Myeloid Leukemia Cell Line ML-1 and Its Role in TRAIL [Tumor Necrosis Factor(TNF)-Related Apoptosis-Inducing Ligand] and TNFa Induced Apoptosis
Published in Blood (16-11-2005)“…TRAIL initiates activation of Caspase-8, which is blocked by the FLICE inhibitory protein (FLIP), resulting in resistance to apoptosis. Here we show that…”
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Journal Article -
14
Artificial Intelligence Assisted Service Marketing Using Deep Assisted Neural Network
Published in 2023 International Conference on Research Methodologies in Knowledge Management, Artificial Intelligence and Telecommunication Engineering (RMKMATE) (01-11-2023)“…Improving marketing abilities, the quality of one product, and one connections with one target audience are at the service marketing approach. The marketing of…”
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Conference Proceeding -
15
Random Forest-Based Retail Management To Improve The Recognition Rates Of Employees
Published in 2023 International Conference on Research Methodologies in Knowledge Management, Artificial Intelligence and Telecommunication Engineering (RMKMATE) (01-11-2023)“…In this paper, we use residual neural network to improve the recognition rates of employees in retail industry sectors. Utilizing data analytics techniques for…”
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Conference Proceeding -
16
Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines
Published in Leukemia & lymphoma (01-01-2007)“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces programmed cell death (apoptosis) preferentially in tumor cells. However, not all…”
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Journal Article -
17
Role of FLICE Inhibitory Protein (FLIP) in myelodysplastic syndromes
Published 01-01-2006“…Myelodysplastic Syndromes (MDSs) are clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis and a propensity to evolve into acute…”
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Dissertation