Search Results - "Seabright, R."

Extracellular Nm23H1 stimulates neurite outgrowth from dorsal root ganglia neurons in vitro independently of nerve growth factor supplementation or its nucleoside diphosphate kinase activity by Wright, K.T., Seabright, R., Logan, A., Lilly, A.J., Khanim, F., Bunce, C.M., Johnson, W.E.B.

“…► Extracellular Nm23H1 stimulates nerve growth. ► Extracellular Nm23H1 provides pathfinding cues to growth cones. ► The neurotrophic activity of Nm23H1 is…”
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TACE-induced cleavage of NgR and p75 super(NTR) in dorsal root ganglion cultures disinhibits outgrowth and promotes branching of neurites in the presence of inhibitory CNS myelin by Ahmed, Z, Mazibrada, G, Seabright, R J, Dent, R G, Berry, M, Logan, A

“…After binding, central nervous system (CNS) myelin-derived axon growth inhibitory ligands, the Nogo-66 receptor (NgR), complexes with LINGO-1 and either the…”
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Disinhibition of neurotrophin-induced dorsal root ganglion cell neurite outgrowth on CNS myelin by siRNA-mediated knockdown of NgR, p75 super(N) super(T) super(R) and Rho-A by Ahmed, Z, Dent, R G, Suggate, EL, Barrett, L B, Seabright, R J, Berry, M, Logan, A

“…The presence of multiple axon growth inhibitors may partly explain why central nervous system axons are generally incapable of regenerating after injury. Using…”
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