Search Results - "Scutt, James N"
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Stereocontrolled Synthesis of 3-(trans-2-Aminocyclopropyl)alanine, a Key Component of Belactosin A
Published in Organic letters (26-06-2003)“…Herein we report a concise synthesis of 3-(trans-2-aminocyclopropyl)alanine, a component of belactosin A, using asymmetric alkylation of a glycine enolate in…”
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2
Diphosphine Complexes of Nickel(II) Are Efficient Catalysts for the Polymerization and Oligomerization of Ethylene: Steric Activation and Ligand Backbone Effects
Published in Organometallics (20-12-2004)“…Nickel(II) complexes of ligands of the type Ar2PCH2PAr2 and 1,2-Ar2PC6H4PAr2 (Ar = ortho-substituted phenyl) are active catalysts for polymerization and…”
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3
Herbicidal aryldiones incorporating a 5-methoxy-[1,2,5]triazepane ring
Published in Bioorganic & medicinal chemistry letters (01-02-2018)“…[Display omitted] Novel 2-aryl-cyclic-1,3-diones containing a 5-methoxy-[1,2,5]triazepane unit were explored towards an effective and wheat safe control of…”
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4
Optimization of Manganese Coupling Reaction for Kilogram-Scale Preparation of Two Aryl-1,3-dione Building Blocks
Published in Organic process research & development (20-10-2017)“…Aryl-1,3-diones represent a promising new class of herbicidal acetyl-CoA carboxylase (ACCase) inhibitors. The original synthesis of this structural motif…”
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5
Amine-Promoted Synthesis of Vinyl Aziridines
Published in Journal of organic chemistry (21-05-2010)“…N-Unsubstituted vinyl aziridines were synthesized via an amine-promoted regioselective nucleophilic aziridination of α,β,γ,δ-unsaturated carbonyl compounds…”
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6
Total synthesis of (+)-belactosin A
Published in Chemical communications (Cambridge, England) (07-03-2004)“…A concise first total synthesis of the antitumour antibiotic belactosin A is reported, involving coupling of beta-lactone carboxylic acid 3 with…”
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7
Organocatalytic Synthesis of β-Alkylaspartates via β-Lactone Ring Opening
Published in Journal of organic chemistry (12-10-2007)“…Cinchona alkaloid-catalyzed reaction of ethyl glyoxylate with substituted ketenes, formed in situ, gives disubstituted β-lactones in moderate yield and high…”
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8
Tertiary amine-promoted enone aziridination: investigations into factors influencing enantioselective induction
Published in Tetrahedron: asymmetry (15-01-2014)“…trans-N-Unsubstituted aziridines were synthesised (up to 77% ee) via a chiral tertiary amine-promoted nucleophilic aziridination of α,β-unsaturated ketones…”
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