Search Results - "Scuto, A"

Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma by Bouska, A, Zhang, W, Gong, Q, Iqbal, J, Scuto, A, Vose, J, Ludvigsen, M, Fu, K, Weisenburger, D D, Greiner, T C, Gascoyne, R D, Rosenwald, A, Ott, G, Campo, E, Rimsza, L M, Delabie, J, Jaffe, E S, Braziel, R M, Connors, J M, Wu, C-I, Staudt, L M, D‘Amore, F, McKeithan, T W, Chan, W C

“…Follicular lymphoma (FL) is typically an indolent disease, but 30–40% of FL cases transform into an aggressive lymphoma (tFL) with a poor prognosis. To…”
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The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival by Scuto, A, Krejci, P, Popplewell, L, Wu, J, Wang, Y, Kujawski, M, Kowolik, C, Xin, H, Chen, L, Kretzner, L, Yu, H, Wilcox, W R, Yen, Y, Forman, S, Jove, R

“…IL-6 and downstream JAK-dependent signaling pathways have critical roles in the pathophysiology of multiple myeloma (MM). We investigated the effects of a…”
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Data on the design optimization, indoor characterization and outdoor testing of GaAs/Bifacial Si heterojunction four-terminal photovoltaic systems by Scuto, A., Corso, R., Leonardi, M., Milazzo, R.G., Privitera, S.M.S., Colletti, C., Foti, M., Bizzarri, F., Gerardi, C., Lombardo, S.

“…The development of a highly efficient multijunction technology is a key challenge for the future of photovoltaic and for the transition to more renewable…”
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SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells by Scuto, A, Kirschbaum, M, Buettner, R, Kujawski, M, Cermak, J M, Atadja, P, Jove, R

“…We explored the activity of SIRT1 activators (SRT501 and SRT2183) alone and in combination with panobinostat in a panel of malignant lymphoid cell lines in…”
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Investigation of recovery mechanisms in dye sensitized solar cells by Chiappara, C., Figà, V., Di Marco, G., Calogero, G., Citro, I., Scuto, A., Lombardo, S., Pignataro, B., Principato, F.

“…•Spontaneous recovery of the short-circuit current and the open-voltage in DSSC.•This recovery does not depend on the temperature and electrolyte…”
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Interferon-gamma, tumor necrosis factor-alpha, and lipopolysaccharide promote chitotriosidase gene expression in human macrophages by Malaguarnera, L., Musumeci, M., Di Rosa, M., Scuto, A., Musumeci, S.

“…Human chitotriosidase (Chit), a chitinolytic enzyme, is a member of the chitinase family. In human plasma, Chit activity has been proposed as a biochemical…”
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Prolactin increases HO-1 expression and induces VEGF production in human macrophages by Malaguarnera, L., Imbesi, R.M., Scuto, A., D'Amico, F., Licata, F., Messina, A., Sanfilippo, S.

“…The pituitary hormone prolactin (PRL) is a multifunctional polypeptide which exerts a role on cell proliferation and may also contribute to cell…”
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Action of prolactin, IFN-γ, TNF-α and LPS on heme oxygenase-1 expression and VEGF release in human monocytes/macrophages by Malaguarnera, L., Imbesi, R., Di Rosa, M., Scuto, A., Castrogiovanni, P., Messina, A., Sanfilippo, S.

“…The pituitary hormone prolactin (PRL) has recently been regarded as a local regulator of macrophage responses. Our goal in this study was to investigate the…”
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Outdoor performance of GaAs/bifacial Si heterojunction four-terminal system using optical spectrum splitting by Scuto, A., Corso, R., Leonardi, M., Milazzo, R.G., M. S. Privitera, S., Colletti, C., Foti, M., Bizzarri, F., Gerardi, C., Lombardo, S.A.

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Performance increase of tandem amorphous/microcrystalline Si PV devices under variable illumination and temperature conditions by Ricco Galluzzo, F., Scuto, A., Gerardi, C., Battaglia, A., Canino, A., Lombardo, S.

“…Wear out in the maximum power point condition of tandem microcrystalline Si/amorphous Si thin film PV modules due to extended light soaking is a well-known…”
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Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3 by George, Prince, Bali, Purva, Annavarapu, Srinivas, Scuto, Anna, Fiskus, Warren, Guo, Fei, Sigua, Celia, Sondarva, Gautam, Moscinski, Lynn, Atadja, Peter, Bhalla, Kapil

“…Present studies show that LBH589, a novel cinnamic hydroxamic acid analog histone deacetylase inhibitor, induces acetylation of histone H3 and H4 and of heat…”
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Prediction of radiation sensitivity using a gene expression classifier by TORRES-ROCA, Javier F, ESCHRICH, Steven, JOVE, Richard, YEATMAN, Timothy, HAIYAN ZHAO, BLOOM, Gregory, SUNG, Jimmy, MCCARTHY, Susan, CANTOR, Alan B, SCUTO, Anna, CHANGGONG LI, SUMING ZHANG

“…The development of a successful radiation sensitivity predictive assay has been a major goal of radiation biology for several decades. We have developed a…”
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Mechanistic role of heat shock protein 70 in Bcr-Abl–mediated resistance to apoptosis in human acute leukemia cells by Guo, Fei, Sigua, Celia, Bali, Purva, George, Prince, Fiskus, Warren, Scuto, Anna, Annavarapu, Srinivas, Mouttaki, Abdelmoughite, Sondarva, Gautam, Wei, Sheng, Wu, Jie, Djeu, Julie, Bhalla, Kapil

“…Bcr-Abl–expressing primary or cultured leukemia cells display high levels of the antiapoptotic heat shock protein (hsp) 70 and are resistant to cytarabine…”
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Cotreatment with 17-allylamino-demethoxygeldanamycin and FLT-3 kinase inhibitor PKC412 is highly effective against human acute myelogenous leukemia cells with mutant FLT-3 by GEORGE, Prince, BALI, Purva, MOSCINSKI, Lynn, BHALLA, Kapil, COHEN, Pamela, JIANGUO TAO, FEI GUO, SIGUA, Celia, VISHVANATH, Anasuya, FISKUS, Warren, SCUTO, Anna, ANNAVARAPU, Srinivas

“…Presence of the activating length mutation (LM) in the juxtamembrane domain or point mutation in the kinase domain of FMS-like tyrosine kinase-3 (FLT-3)…”
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Superior Activity of the Combination of Histone Deacetylase Inhibitor LAQ824 and the FLT-3 Kinase Inhibitor PKC412 against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3 by BALI, Purva, GEORGE, Prince, MOSCINSKI, Lynn, ATADJA, Peter, BHALLA, Kapil, COHEN, Pamela, JIANGUO TAO, FEI GUO, SIGUA, Celia, VISHVANATH, Anasuya, SCUTO, Anna, ANNAVARAPU, Srinivas, FISKUS, Warren

“…Purpose: Mutant FLT-3 receptor tyrosine kinase is a client protein of the molecular chaperone heat shock protein 90 and is commonly present and contributes to…”
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Effect of interferon-gamma, interleukin-10, lipopolysaccharide and tumor necrosis factor-alpha on chitotriosidase synthesis in human macrophages by Di Rosa, Michelino, Musumeci, Maria, Scuto, Anna, Musumeci, Salvatore, Malaguarnera, Lucia

“…Human chitotriosidase is a chitinolytic enzyme and mainly produced by activated macrophages. Recently, we observed that prolactin, which is structurally…”
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Survivin expression in chronic myeloid leukemia by Conte, Enrico, Stagno, Fabio, Guglielmo, Patrizia, Scuto, Anna, Consoli, Carla, Messina, Angelo

“…In this study, we investigated the expression of survivin (SVV) in 44 patients with typical Ph-positive chronic myeloid leukemia (CML) in different phases of…”
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SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-[kappa]B/STAT3 complex to its promoter in malignant lymphoid cells by Scuto, A, Kirschbaum, M, Buettner, R, Kujawski, M, Cermak, J M, Atadja, P, Jove, R

“…We explored the activity of SIRT1 activators (SRT501 and SRT2183) alone and in combination with panobinostat in a panel of malignant lymphoid cell lines in…”
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Prolactin trigger VEGF synthesis and heme oxygenase-1 overexpression in human macrophages by Malaguarnera, L, Imbesi, R M, Pilastro, M R, Scuto, A

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Abstract 981: SRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-kB/STAT3 complex to its promoter in malignant lymphoid cells by Scuto, Anna A. G., Kirschbaum, Mark, Buettner, Ralf, Cermak, Jennifer M., Atadja, Peter, Jove, Richard

“…Abstract SIRT1 is an NAD+-dependent class III histone deacetylase, which is not affected directly by HDAC inhibitors (HDACi). It remains controversial whether…”
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