Search Results - "Scsukova, Sona"

Effect of selected bisphenol derivatives on nuclear receptor expression in ovarian cell line COV434 by Mlynarcikova, Alzbeta Bujnakova, Scsukova, Sona

“…Bisphenol A (BPA), as an indispensable plastic additive, has also been proven as an endocrine disruptor associated with adverse health effects including…”
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Impact of endocrine disrupting chemicals on onset and development of female reproductive disorders and hormone-related cancer by Scsukova, Sona, PhD, Rollerova, Eva, Bujnakova Mlynarcikova, Alzbeta

“…Abstract A growing body of evidence suggests that exposure to chemical substances designated as endocrine disrupting chemicals (EDCs) due to their ability to…”
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Expression of selected nuclear receptors in human epithelial ovarian cell line Caov3 exposed to bisphenol derivatives by Mlynarcikova, Alzbeta Bujnakova, Macejova, Dana, Scsukova, Sona

“…Bisphenol A (BPA) is an indispensable industrial chemical. However, as a proven endocrine disruptor, it may be associated with several health disturbances,…”
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Unique hyaluronan structure of expanded oocyte-cumulus extracellular matrix in ovarian follicles by Nagyova, Eva, Mlynarcikova, Alzbeta Bujnakova, Nemcova, Lucie, Scsukova, Sona

“…In preovulatory follicles, after the endogenous gonadotropin surge, the oocyte-cumulus complexes (OCCs) produce hyaluronan (HA) in a process called “cumulus…”
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Versican G1 Fragment Establishes a Strongly Stabilized Interaction with Hyaluronan-Rich Expanding Matrix during Oocyte Maturation by Nagyova, Eva, Salustri, Antonietta, Nemcova, Lucie, Scsukova, Sona, Kalous, Jaroslav, Camaioni, Antonella

“…In the mammalian ovary, the hyaluronan (HA)-rich cumulus extracellular matrix (ECM) organized during the gonadotropin-induced process of oocyte maturation is…”
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The use of ex vivo ovary culture for assessment of alterations in steroidogenesis following neonatal exposure to poly(ethylene glycol)-block-polylactide methyl ether or titanium dioxide nanoparticles in Wistar rats by Scsukova, Sona, Mlynarcikova, Alzbeta Bujnakova, Rollerova, Eva

“…Rapid development and widespread application of different types of nanoparticles (NPs) may result in increased exposure of humans and animals to NPs. Recently,…”
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Plant isoflavones can affect accumulation and impact of silver and titania nanoparticles on ovarian cells by Sirotkin, Alexander V., Alexa, Richard, Stochmalova, Aneta, Scsukova, Sona

“…The application of nanoparticles is experiencing a rapid growth, but it faces a problem of their toxicity, especially adverse effects on female reproduction…”
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Activation of cumulus cell SMAD2/3 and epidermal growth factor receptor pathways are involved in porcine oocyte-cumulus cell expansion and steroidogenesis by Nagyova, Eva, Camaioni, Antonella, Scsukova, Sona, Mlynarcikova, Alzbeta, Prochazka, Radek, Nemcova, Lucie, Salustri, Antonietta

“…Several lines of evidence suggest that in mice the activation of SMAD2/3 signaling by oocyte secreted factors, together with epidermal growth factor receptor…”
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Lapatinib inhibits meiotic maturation of porcine oocyte-cumulus complexes cultured in vitro in gonadotropin-supplemented medium by Nagyova, Eva, D.V.M., Ph.D, Nemcova, Lucie, Ph.D, Mlynarcikova, Alzbeta, Ph.D, Scsukova, Sona, Ph.D, Kalous, Jaroslav, Ph.D

“…Objective To determine whether inhibition of epidermal growth factor (EGF) receptor tyrosine kinase with lapatinib affects oocyte maturation, expression of the…”
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Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells by Scsukova, Sona, Bujnakova, Mlynarcikova A., Kiss, A., Rollerova, E.

“…Objectives. Development of nanoparticles (NPs) for biomedical applications, including medical imaging and drug delivery, is currently undergoing a dramatic…”
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Evaluation of effects of bisphenol analogs AF, S, and F on viability, proliferation, production of selected cancer-related factors, and expression of selected transcripts in Caov-3 human ovarian epithelial cell line by Bujnakova Mlynarcikova, Alzbeta, Scsukova, Sona

“…Bisphenol A (BPA) has been a substantial additive in plastics until the reports on its adverse effects have led to its restrictions and replacement. Monitoring…”
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Bisphenol analogs AF and S: Effects on cell status and production of angiogenesis-related factors by COV434 human granulosa cell line by Bujnakova Mlynarcikova, Alzbeta, Scsukova, Sona

“…While Bisphenol A (BPA) has been a requisite plastic additive, as an endocrine disruptor it has been associated with adverse health effects including ovarian…”
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Bisphenol analogs AF, S and F: Effects on functional characteristics of porcine granulosa cells by Bujnakova Mlynarcikova, Alzbeta, Scsukova, Sona

“…•BPAF, BPS and BPF (10−4 M) decreased FSH-stimulated progesterone production.•BPS significantly inhibited estradiol production from the concentration of 10−6…”
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Simultaneous effects of endocrine disruptor bisphenol A and flavonoid fisetin on progesterone production by granulosa cells by Bujnakova Mlynarcikova, Alzbeta, Scsukova, Sona

“…•Flavonoid fisetin altered progesterone production by granulosa cells.•Fisetin was not able to restore progesterone synthesis impaired by the high dose of the…”
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Assessment of the Potential Health Risk of Gold Nanoparticles Used in Nanomedicine by Dvorakova, Monika, Kuracka, Lubomir, Zitnanova, Ingrid, Scsukova, Sona, Kollar, Jozef, Konarikova, Katarina, Laubertova, Lucia

“…Due to unique properties, nanoparticles (NPs) have become a preferred material in biomedicine. The benefits of their use are indisputable, but their safety and…”
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Development of functional LH Receptors on pig cumulus-oocyte complexes cultured in vitro by a novel two-step culture system by PROCHAZKA, Radek, NEMCOVA, Lucie, NAGYOVA, Eva, SCSUKOVA, Sona, MLYNARCIKOVA, Alzbeta

“…We show in the present study that freshly isolated pig cumulus–oocyte complexes (COCs) display a limited response to LH, as assessed by the expression of…”
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Delayed adverse effects of neonatal exposure to polymeric nanoparticle poly(ethylene glycol)-block-polylactide methyl ether on hypothalamic–pituitary–ovarian axis development and function in Wistar rats by Rollerova, Eva, Jurcovicova, Jana, Mlynarcikova, Alzbeta, Sadlonova, Irina, Bilanicova, Dagmar, Wsolova, Ladislava, Kiss, Alexander, Kovriznych, Jevgenij, Kronek, Juraj, Ciampor, Fedor, Vavra, Ivo, Scsukova, Sona

“…•Neonatal exposure to polymeric nanoparticle PEG-b-PLA in female Wistar rats.•Delayed effects on hypothalamic–pituitary–ovarian axis development and function…”
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The toxic influence of silver and titanium dioxide nanoparticles on cultured ovarian granulosa cells by Sirotkin, Alexander V., Bauer, Miroslav, Kadasi, Attila, Makovicky, Pavol, Scsukova, Sona

“…The application of metal nanoparticles in modern society is growing, but there is insufficient data concerning their influence on reproductive processes and…”
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Effect of polymeric nanoparticle poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA) on in vitro luteinizing hormone release from anterior pituitary cells of infantile and adult female rats by Scsukova, Sona, Mlynarcikova, Alzbeta, Kiss, Alexander, Rollerova, Eva

“…Polymeric PEG-b-PLA nanoparticles (NPs) were developed for delivery of poorly water-soluble drugs via blood brain barrier into brain parenchyma. We analyzed…”
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Endocrine-modulating effects of polymeric nanoparticle poly (ethylene glycol)-block-poly (lactic acid) (PEG-b-PLA) on ovarian steroidogenesis by Scsukova, Sona, Mlynarcikova, Alzbeta, Smolikova, Kvetoslava, Kiss, Alexander, Rollerova, Eva

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