Search Results - "Scroggins, Sabrina M."

Cellular Immunotherapy in Mice Prevents Maternal Hypertension and Restores Anti-Inflammatory Cytokine Balance in Maternal and Fetal Tissues by Gray, Gabrielle, Scroggins, Douglas G, Wilson, Katlin T, Scroggins, Sabrina M

“…Preeclampsia is the leading cause of maternal–fetal morbidity worldwide. The concept that persistent feto-placental intolerance is important in the…”
Get full text

Generation of Human Regulatory Dendritic Cells from Cryopreserved Healthy Donor Cells and Hematopoietic Stem Cell Transplant Recipients by Scroggins, Sabrina M, Schlueter, Annette J

“…Acute graft versus host disease (GVHD) remains a significant complication following hematopoietic stem cell transplant (HSCT), despite improved human leukocyte…”
Get full text

Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia by Scroggins, Sabrina M, Santillan, Donna A, Lund, Jenna M, Sandgren, Jeremy A, Krotz, Lindsay K, Hamilton, Wendy S, Devor, Eric J, Davis, Heather A, Pierce, Gary L, Gibson-Corley, Katherine N, Sigmund, Curt D, Grobe, Justin L, Santillan, Mark K

“…The pathogenesis of preeclampsia (PreE), a hypertensive disorder of pregnancy, involves imbalanced T helper (T ) cell populations and resultant changes in pro-…”
Get more information

Efferocytosis of viable versus heat-inactivated MSC induces human monocytes to distinct immunosuppressive phenotypes by Schrodt, Michael V, Behan-Bush, Riley M, Liszewski, Jesse N, Humpal-Pash, Madeleine E, Boland, Lauren K, Scroggins, Sabrina M, Santillan, Donna A, Ankrum, James A

“…Immunomodulation by mesenchymal stromal cells (MSCs) can occur through trophic factor mechanisms, however, intravenously infused MSCs are rapidly cleared from…”
Get full text

Reduced Maternal Circulating Cell-Free Mitochondrial DNA Is Associated With the Development of Preeclampsia by Cushen, Spencer C, Ricci, Contessa A, Bradshaw, Jessica L, Silzer, Talisa, Blessing, Alexandra, Sun, Jie, Zhou, Zhengyang, Scroggins, Sabrina M, Santillan, Mark K, Santillan, Donna A, Phillips, Nicole R, Goulopoulou, Styliani

“…Background Circulating cell-free mitochondrial DNA (ccf-mtDNA) is a damage-associated molecular pattern that reflects cell stress responses and tissue damage,…”
Get full text

Association between plasma leptin and cesarean section after induction of labor: a case control study by Cowman, Whitney, Scroggins, Sabrina M, Hamilton, Wendy S, Karras, Alexandra E, Bowdler, Noelle C, Devor, Eric J, Santillan, Mark K, Santillan, Donna A

“…Obesity in pregnancy is common, with more than 50% of pregnant women being overweight or obese. Obesity has been identified as an independent predictor of…”
Get full text

330 Maternal hypertension results in a decreased number of glial cells in offspring during early development by Scroggins, Sabrina M., Brummond, Dan, Mikkelsen, Emma, Bunton, Olivia, Scroggins, Douglas G.

“…OBJECTIVES/GOALS: Preeclampsia, a hypertensive disorder in pregnancy, disrupts immune cell profiles at birth in both mice and humans. In mice, it affects…”
Get full text

Characterization of regulatory dendritic cells that mitigate acute graft-versus-host disease in older mice following allogeneic bone marrow transplantation by Scroggins, Sabrina M, Olivier, Alicia K, Meyerholz, David K, Schlueter, Annette J

“…Despite improvements in human leukocyte antigen matching and pharmacologic prophylaxis, acute graft-versus-host disease (GVHD) is often a fatal complication…”
Get full text

Vasopressin in Preeclampsia: A Novel Very Early Human Pregnancy Biomarker and Clinically Relevant Mouse Model by Santillan, Mark K, Santillan, Donna A, Scroggins, Sabrina M, Min, James Y, Sandgren, Jeremy A, Pearson, Nicole A, Leslie, Kimberly K, Hunter, Stephen K, Zamba, Gideon K.D, Gibson-Corley, Katherine N, Grobe, Justin L

“…Preeclampsia, a cardiovascular disorder of late pregnancy, is characterized as a low-renin hypertensive state relative to normotensive pregnancy. Because other…”
Get full text

Placenta-specific protein 1 (PLAC1) expression is significantly down-regulated in preeclampsia via a hypoxia-mediated mechanism by Devor, Eric J., Santillan, Donna A., Warrier, Akshaya, Scroggins, Sabrina M., Santillan, Mark K.

“…Examine a mechanism of PLAC1 regulation and its potential role in preeclampsia (PE). Placental tissue samples and detailed clinical information were obtained…”
Get full text

Beat-to-Beat Blood Pressure Variability in the First Trimester Is Associated With the Development of Preeclampsia in a Prospective Cohort: Relation With Aortic Stiffness by Nuckols, Virginia R., Holwerda, Seth W., Luehrs, Rachel E., DuBose, Lyndsey E., Stroud, Amy K., Brandt, Debra, Betz, Alexandria M., Fiedorowicz, Jess G., Scroggins, Sabrina M., Santillan, Donna A., Grobe, Justin L., Sigmund, Curt D., Santillan, Mark K., Pierce, Gary L.

“…Women with preeclampsia, a hypertensive disorder of pregnancy, exhibit greater beat-to-beat blood pressure variability (BPV) in the third trimester after…”
Get full text

Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice by Perschbacher, Katherine J., Deng, Guorui, Sandgren, Jeremy A., Walsh, John W., Witcher, Phillip C., Sapouckey, Sarah A., Owens, Caitlyn E., Zhang, Shao Yang, Scroggins, Sabrina M., Pearson, Nicole A., Devor, Eric J., Sebag, Julien A., Pierce, Gary L., Fisher, Rory A., Kwitek, Anne E., Santillan, Donna A., Gibson-Corley, Katherine N., Sigmund, Curt D., Santillan, Mark K., Grobe, Justin L.

“…Cascade-specific termination of G protein signaling is catalyzed by the RGS (regulator of G protein signaling) family members, including RGS2. Angiotensin,…”
Get full text

Selective Serotonin Reuptake Inhibitor Use in Pregnancy and Protective Mechanisms in Preeclampsia by Vignato, Julie A, Gumusoglu, S Banu, Davis, Heather A, Scroggins, Sabrina M, Hamilton, Wendy S, Brandt, Debra S, Pierce, Gary L, Knosp, Boyd A, Santillan, Donna A, Santillan, Mark K

“…Depression and preeclampsia share risk factors and are bi-directionally associated with increased risk for each other. Despite epidemiological evidence linking…”
Get more information

Vasopressin: the missing link for preeclampsia? by Sandgren, Jeremy A, Scroggins, Sabrina M, Santillan, Donna A, Devor, Eric J, Gibson-Corley, Katherine N, Pierce, Gary L, Sigmund, Curt D, Santillan, Mark K, Grobe, Justin L

“…Preeclampsia is a devastating cardiovascular disorder of late pregnancy, affecting 5-7% of all pregnancies and claiming the lives of 76,000 mothers and 500,000…”
Get more information

Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice by Sandgren, Jeremy A, Deng, Guorui, Linggonegoro, Danny W, Scroggins, Sabrina M, Perschbacher, Katherine J, Nair, Anand R, Nishimura, Taryn E, Zhang, Shao Yang, Agbor, Larry N, Wu, Jing, Keen, Henry L, Naber, Meghan C, Pearson, Nicole A, Zimmerman, Kathy A, Weiss, Robert M, Bowdler, Noelle C, Usachev, Yuriy M, Santillan, Donna A, Potthoff, Matthew J, Pierce, Gary L, Gibson-Corley, Katherine N, Sigmund, Curt D, Santillan, Mark K, Grobe, Justin L

“…Copeptin, a marker of arginine vasopressin (AVP) secretion, is elevated throughout human pregnancies complicated by preeclampsia (PE), and AVP infusion…”
Get full text

Pregnant mice lacking indoleamine 2,3‐dioxygenase exhibit preeclampsia phenotypes by Santillan, Mark K., Pelham, Christopher J., Ketsawatsomkron, Pimonrat, Santillan, Donna A., Davis, Deborah R., Devor, Eric J., Gibson‐Corley, Katherine N., Scroggins, Sabrina M., Grobe, Justin L., Yang, Baoli, Hunter, Steven K., Sigmund, Curt D.

“…Preeclampsia is a cardiovascular disorder of late pregnancy that is, commonly characterized by hypertension, renal structural damage and dysfunction, and fetal…”
Get full text

Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice by Sandgren, Jeremy A., Deng, Guorui, Linggonegoro, Danny W., Scroggins, Sabrina M., Perschbacher, Katherine J., Nair, Anand R., Nishimura, Taryn E., Zhang, Shao Yang, Agbor, Larry N., Wu, Jing, Keen, Henry L., Naber, Meghan C., Pearson, Nicole A., Zimmerman, Kathy A., Weiss, Robert M., Bowdler, Noelle C., Usachev, Yuriy M., Santillan, Donna A., Potthoff, Matthew J., Pierce, Gary L., Gibson-Corley, Katherine N., Sigmund, Curt D., Santillan, Mark K., Grobe, Justin L.

Get full text

Abstract P209: Loss Of Rgs2 Specifically In CD4+ T Cells Decreases The Hypertensive Response To Vasopressin by Scroggins, Sabrina M, Gray, Gabrielle, Scroggins, Douglas G, Shaw, Kamara S, Santillan, Donna A, Grobe, Justin L, Santillan, Mark K

“…Regulator of G protein Signaling (RGS) family members can modulate multiple cardiovascular hormones and are associated with hypertension and preeclampsia, a…”
Get full text

Trimester-specific plasma exosome microRNA expression profiles in preeclampsia by Devor, Eric, Santillan, Donna, Scroggins, Sabrina, Warrier, Akshaya, Santillan, Mark

“…Objective: To identify microRNAs (miRNAs) differentially expressed in plasma exosomes collected in women diagnosed with preeclampsia compared with women with…”
Get full text

Novel Mechanisms of Preeclampsia Prevention via SGK1 by Lo, Carolyn C, Scroggins, Sabrina M, Devor, Eric J, Santillan, Donna A, Santillan, Mark K

“…Preeclampsia (PE), a hypertensive disorder of pregnancy, involves poor trophoblast invasion, poor spiral artery remodeling, and an early systemic inflammatory…”
Get full text