Prognostic value of the qualitative assessments of general movements in late-preterm infants

Prognostic value of the qualitative assessments of general movements in late-preterm infants

Abstract Background The quality of general movements (GMs) and its predictive value have never been evaluated in late-preterm (LP) infants. Aims To determine the characteristics of GMs and their predictive value for neurodevelopmental outcome in a cohort of infants born between 34 and 36 weeks'...

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Bibliographic Details
Published in:Early human development Vol. 89; no. 12; pp. 1063 - 1066
Main Authors: Brogna, Claudia, Romeo, Domenico M, Cervesi, Chiara, Scrofani, Luana, Romeo, Mario G, Mercuri, Eugenio, Guzzetta, Andrea
Format: Journal Article
Language:English
Published: Ireland Elsevier Ireland Ltd 01-12-2013
Subjects:
Advanced Basic Science
Age Factors
Cerebral palsy
Cerebral Palsy - diagnosis
Child Development - physiology
Child, Preschool
General movements
Humans
Infant, Newborn
Infant, Premature - physiology
Italy
Late preterm
Movement - physiology
Neonatal and Perinatal Medicine
Neurological outcome
Predictive Value of Tests
Sensitivity and Specificity
Italy
Cerebral palsy
Late preterm
General movements
Neurological outcome
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Summary:Abstract Background The quality of general movements (GMs) and its predictive value have never been evaluated in late-preterm (LP) infants. Aims To determine the characteristics of GMs and their predictive value for neurodevelopmental outcome in a cohort of infants born between 34 and 36 weeks' gestation. Study design and subjects 574 LP infants were examined using the standard methodological principles of Prechtl's method for assessing GMs both during writhing and fidgety periods. Outcome measures Infants were assessed at 2 years of age with neuromotor and developmental scales. Results A significant correlation was found between GMs and outcome both at writhing (rs 0.68; p < 0.001) and at fidgety age (rs 0.78; p < 0.001). The assessment at 1 month showed 100% sensitivity and 86% specificity of predicting the development of cerebral palsy (CP), that at 3 months was 100% sensitivity and 97% specificity. Conclusions During the fidgety age GMs predict CP with very high sensitivity and specificity. The qualitative assessment of GMs should be employed to help identify LP infants who require early intervention for neurological abnormalities.
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ISSN:0378-3782
1872-6232
DOI:10.1016/j.earlhumdev.2013.08.008