Search Results - "Scotto D'Abusco, Anna"
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Intron retention in PI‐PLC γ1 mRNA as a key mechanism affecting MMP expression in human primary fibroblast‐like synovial cells
Published in Cell biochemistry and function (01-07-2024)“…The intron retention (IR) is a phenomenon utilized by cells to allow diverse fates at the same mRNA, leading to a different pattern of synthesis of the same…”
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Split Gp41‐1 intein splicing as a model to evaluate the cellular location of the oncosuppressor Maspin in an in vitro model of osteosarcoma
Published in Cell biochemistry and function (01-03-2024)“…Inteins are proteins involved in the protein splicing mechanism, an autoprocessing event, where sequences (exteins) separated by inteins become ligated each…”
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3
The N-Acetyl Phenylalanine Glucosamine Derivative Attenuates the Inflammatory/Catabolic Environment in a Chondrocyte-Synoviocyte Co-Culture System
Published in Scientific reports (19-09-2019)“…Osteoarthritis (OA), the most prevalent degenerative joint disease, still lacks a true disease-modifying therapy. The involvement of the NF-κB pathway and its…”
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4
The Glucosamine‐derivative NAPA Suppresses MAPK Activation and Restores Collagen Deposition in Human Diploid Fibroblasts Challenged with Environmental Levels of UVB
Published in Photochemistry and photobiology (01-01-2020)“…The ultraviolet (UV) component of solar radiation is the driving force of life on earth, but it can cause photoaging and skin cancer. In this study, we…”
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5
PLA-grafting of collagen chains leading to a biomaterial with mechanical performances useful in tendon regeneration
Published in Journal of the mechanical behavior of biomedical materials (01-12-2016)“…With the aim to obtain a scaffold with improved mechanical properties with respect to collagen for tendon augmentation and regeneration, a novel collagen-based…”
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Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo biocompatibility against 143 B cells
Published in Carbohydrate polymer technologies and applications (01-12-2023)“…Polymers are among the most studied materials as drug carriers, due to their tunable chemical structure and ability to self-assemble to give different types of…”
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7
l-Carnitine enhances extracellular matrix synthesis in human primary chondrocytes
Published in Rheumatology international (01-09-2013)“…Osteoarthritis (OA) is one of the most common degenerative joint disease for which there is no cure. It is treated mainly with non-steroidal anti-inflammatory…”
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Design of bioactive and biomimetic scaffolds based on chitosan-alginate polyelectrolyte complexes for tissue engineering
Published in Carbohydrate polymers (01-03-2024)“…The replacement and regeneration of biological tissues by fabricating three-dimensional functionalized constructs that can improve material interaction with…”
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Glucosamine affects intracellular signalling through inhibition of mitogen-activated protein kinase phosphorylation in human chondrocytes
Published in Arthritis research & therapy (01-01-2007)“…The aim of this study was to determine the effects of glucosamine on matrix metalloprotease (MMP) production, on mitogen-activated protein kinase (MAPK)…”
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10
Chitosan scaffolds with enhanced mechanical strength and elastic response by combination of freeze gelation, photo-crosslinking and freeze-drying
Published in Carbohydrate polymers (01-09-2021)“…In this study, a new scaffold fabrication method based on the combination of a series of stabilization processes was set up to obtain chitosan scaffolds with…”
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Hyaluronic Acid Reduces Bacterial Fouling and Promotes Fibroblasts' Adhesion onto Chitosan 2D-Wound Dressings
Published in International journal of molecular sciences (18-03-2020)“…Wound healing is a dynamic process that can be seriously delayed by many factors including infectious complications. The development of dressings with…”
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Tn2009, a Tn916-Like Element Containing mef(E) in Streptococcus pneumoniae
Published in Antimicrobial Agents and Chemotherapy (01-06-2004)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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13
Preparation and Characterization of TPP-Chitosan Crosslinked Scaffolds for Tissue Engineering
Published in Materials (13-08-2020)“…Scaffolds are three-dimensional porous structures that must have specific requirements to be applied in tissue engineering. Therefore, the study of factors…”
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14
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Published in Current issues in molecular biology (01-08-2022)“…Osteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by…”
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Nutraceuticals and the Network of Obesity Modulators
Published in Nutrients (01-12-2022)“…Obesity is considered an increasingly widespread disease in the world population, regardless of age and gender. Genetic but also lifestyle-dependent causes…”
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In Vitro Antiviral and Anti-Inflammatory Activities of N -Acetylglucosamine: Development of an Alternative and Safe Approach to Fight Viral Respiratory Infections
Published in International journal of molecular sciences (07-03-2023)“…Viral respiratory tract infections (RTIs) are responsible for significant morbidity and mortality worldwide. A prominent feature of severe respiratory…”
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Antiarthritic Effects of a Root Extract from Harpagophytum procumbens DC: Novel Insights into the Molecular Mechanisms and Possible Bioactive Phytochemicals
Published in Nutrients (23-08-2020)“…(Burch.) DC. ex Meisn. is a traditional remedy for osteoarticular diseases, including osteoarthritis (OA), although the bioactive constituents and mechanisms…”
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Metabolomic Profiling of Fresh Goji ( Lycium barbarum L.) Berries from Two Cultivars Grown in Central Italy: A Multi-Methodological Approach
Published in Molecules (Basel, Switzerland) (06-09-2021)“…The metabolite profile of fresh Goji berries from two cultivars, namely Big Lifeberry (BL) and Sweet Lifeberry (SL), grown in the Lazio region (Central Italy)…”
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Repositioned Natural Compounds and Nanoformulations: A Promising Combination to Counteract Cell Damage and Inflammation in Respiratory Viral Infections
Published in Molecules (Basel, Switzerland) (12-05-2023)“…Respiratory viral diseases are among the most important causes of disability, morbidity, and death worldwide. Due to the limited efficacy or side effects of…”
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The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis
Published in Rheumatology international (01-05-2014)“…Osteoarthritis (OA) is a multifactorial degenerative pathology, whose progression is exacerbated by pro-inflammatory cytokines signaling. Among the changes…”
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