Search Results - "Scotti, Maddalena"
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A real time PCR platform for the simultaneous quantification of total and extrachromosomal HIV DNA forms in blood of HIV-1 infected patients
Published in PloS one (03-11-2014)“…The quantitative measurement of various HIV-1 DNA forms including total, unintegrated and integrated provirus play an increasingly important role in HIV-1…”
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Characterization of mec1 Kinase-Deficient Mutants and of New Hypomorphic mec1 Alleles Impairing Subsets of the DNA Damage Response Pathway
Published in Molecular and cellular biology (01-06-2001)“…DNA damage checkpoints lead to the inhibition of cell cycle progression following DNA damage. The Saccharomyces cerevisiae Mec1 checkpoint protein, a…”
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TBX3, the gene mutated in ulnar-mammary syndrome, promotes growth of mammary epithelial cells via repression of p19ARF, independently of p53
Published in Cell and tissue research (01-05-2007)“…TBX3, the gene mutated in ulnar-mammary syndrome (UMS), is involved in the production of a transcription factor of the T-box family, known to inhibit…”
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Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition
Published in BioFactors (Oxford) (10-09-2017)“…Arsenite is an established DNA‐damaging agent and human carcinogen. We initially selected conditions in which the metalloid causes DNA strand scission in the…”
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SVCT2-Dependent plasma and mitochondrial membrane transport of ascorbic acid in differentiating myoblasts
Published in Pharmacological research (01-09-2020)“…[Display omitted] •C2C12 myoblasts and myotubes express high affinity plasma membrane SVCT2.•C2C12 myoblasts express low-affinity mitochondrial SVCT2.•C2C12…”
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The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium
Published in Biochimica et biophysica acta (01-06-2015)“…We recently reported that U937 cell mitochondria express a functional Na+-dependent ascorbic acid (AA) transporter recognised by anti-SVCT2 antibodies. The…”
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Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Growth of promonocytic U937 cells in the presence of DMSO promotes their differentiation to monocytes. After 4 days of culture in differentiating medium, these…”
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Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria
Published in Pharmacological research (01-09-2015)“…[Display omitted] Exposure of U937 cells to low concentrations of l-ascorbic acid (AA) is associated with a prompt cellular uptake and a further mitochondrial…”
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U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin
Published in BioFactors (Oxford) (01-03-2015)“…Summary Arsenite directly triggers cytochrome c and Smac/DIABLO release in mitochondria isolated from U937 cells. These effects were not observed in…”
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A Real Time PCR Platform for the Simultaneous Quantification of Total and Extrachromosomal HIV DNA Forms in Blood of HIV-1 Infected Patients: e111919
Published in PloS one (01-11-2014)“…Background The quantitative measurement of various HIV-1 DNA forms including total, unintegrated and integrated provirus play an increasingly important role in…”
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11
Characterization of mec1Kinase-Deficient Mutants and of New Hypomorphic mec1Alleles Impairing Subsets of the DNA Damage Response Pathway
Published in Molecular and Cellular Biology (15-06-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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