Search Results - "Scott Goebel, W."

Preemptive Approach to Plerixafor Use Is Optimal in Patients With Relapsed/Refractory Germ Cell Tumors Undergoing Peripheral Blood Hematopoietic Stem Cell Collection: Effect on Collection Days, Yields, and Cost by Sohutskay, David O., Tetrick, Anne M., Goebel, W. Scott, Schwering, Dave, Reddy, Manasa S.

“…ABSTRACT Evidence describing the use of plerixafor in the off‐label population of relapsed/refractory germ cell tumors (GCT) is limited. We aim to describe the…”
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Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function by Chitteti, Brahmananda R., Cheng, Ying-Hua, Poteat, Bradley, Rodriguez-Rodriguez, Sonia, Goebel, W. Scott, Carlesso, Nadia, Kacena, Melissa A., Srour, Edward F.

“…Hematopoietic stem (HSC) and progenitor (HPC) cell fate is governed by intrinsic and extrinsic parameters. We examined the impact of hematopoietic niche…”
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The effect of diluted triple and double antibiotic pastes on dental pulp stem cells and established Enterococcus faecalis biofilm by Sabrah, Alaa H. A., Yassen, Ghaeth H., Liu, Wai-Ching, Goebel, W. Scott, Gregory, Richard L., Platt, Jeffrey A.

“…Objectives To investigate the effect of various dilutions of antibiotic medicaments used in endodontic regeneration on the survival of human dental pulp stem…”
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Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis by Rodriguez, Sonia, Chora, Angelo, Goumnerov, Boyan, Mumaw, Christen, Goebel, W. Scott, Fernandez, Luis, Baydoun, Hasan, HogenEsch, Harm, Dombkowski, David M., Karlewicz, Carol A., Rice, Susan, Rahme, Laurence G., Carlesso, Nadia

“…Severe sepsis is one of the leading causes of death worldwide. High mortality rates in sepsis are frequently associated with neutropenia. Despite the central…”
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Donor-matched comparison of dental pulp stem cells and bone marrow-derived mesenchymal stem cells in a rat model by Alge, Daniel L., Zhou, Dan, Adams, Lyndsey L., Wyss, Brandon K., Shadday, Matthew D., Woods, Erik J., Gabriel Chu, T. M., Goebel, W. Scott

“…Dental pulp stem cells (DPSCs) have drawn much interest for the regeneration of mineralized tissues, and several studies have compared DPSCs to bone…”
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Poly(propylene fumarate) reinforced dicalcium phosphate dihydrate cement composites for bone tissue engineering by Alge, Daniel L., Bennett, Jeffrey, Treasure, Trevor, Voytik-Harbin, Sherry, Goebel, W. Scott, Chu, Tien-Min Gabriel

“…Calcium phosphate cements have many desirable properties for bone tissue engineering, including osteoconductivity, resorbability, and amenability to rapid…”
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Clinical grade adult stem cell banking by Thirumala, Sreedhar, Goebel, W. Scott, Woods, Erik J.

“…There has been a great deal of scientific interest recently generated by the potential therapeutic applications of adult stem cells in human care but there are…”
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Collection, cryopreservation, and characterization of human dental pulp-derived mesenchymal stem cells for banking and clinical use by Perry, Brandon C, Zhou, Dan, Wu, Xiaohua, Yang, Feng-Chun, Byers, Michael A, Chu, T-M Gabriel, Hockema, J Jeffrey, Woods, Erik J, Goebel, W Scott

“…Recent studies have shown that mesenchymal stem cells (MSC) with the potential for cell-mediated therapies and tissue engineering applications can be isolated…”
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Humanized Bone Marrow Mouse Model as a Preclinical Tool to Assess Therapy-Mediated Hematotoxicity by SHANBAO CAI, HAIYAN WANG, SCOTT GOEBEL, W, POLLOK, Karen E, BAILEY, Barbara, ERNSTBERGER, Aaron, JULIAR, Beth E, SINN, Anthony L, CHAN, Rebecca J, JONES, David R, MAYO, Lindsey D, BALUYUT, Arthur R

“…Preclinical in vivo studies can help guide the selection of agents and regimens for clinical testing. However, one of the challenges in screening anticancer…”
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Fabrication of Poly-l-lactic Acid/Dicalcium Phosphate Dihydrate Composite Scaffolds with High Mechanical Strength-Implications for Bone Tissue Engineering by Tanataweethum, Nida, Liu, Wai Ching, Goebel, W Scott, Li, Ding, Chu, Tien Min

“…Scaffolds were fabricated from poly-l-lactic acid (PLLA)/dicalcium phosphate dihydrate (DCPD) composite by indirect casting. Sodium citrate and PLLA were used…”
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Primed for change: The effect of a blood prime on peripheral blood stem cell collection and accuracy of a prediction tool in pediatric patients by Rahim, Mahvish Q, Goebel, W Scott, Delph, John, Soundar, Esther

“…Pediatric apheresis collection of peripheral blood stem cells for autologous transplantation often requires use of a blood prime. We evaluated the relationship…”
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Manufacturing and banking of mesenchymal stem cells by Thirumala, Sreedhar, Goebel, W Scott, Woods, Erik J

“…Mesenchymal stem cells (MSC) and MSC-like cells hold great promise and offer many advantages for developing effective cellular therapeutics. Current trends…”
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Disseminated toxoplasmosis resulting in graft failure in a cord blood stem cell transplant recipient by Goebel, W. Scott, Conway, James H., Faught, Philip, Vakili, Saeed T., Haut, Paul R.

“…Toxoplasmosis is an infrequent infection with a high mortality rate in hematopoietic stem cell transplant recipients, and is usually caused by reactivation of…”
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Unrelated cord blood transplantation for severe congenital neutropenia: Report of two cases with very different transplant courses by Markel, Melissa K., Haut, Paul R., Renbarger, Jamie A., Robertson, Kent A., Scott Goebel, W.

“…:  SCN is characterized by neutropenia, life‐threatening infections, and progression to myelodysplastic syndrome/acute myelogenous leukemia. The only curative…”
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Granulocyte Colony‐Stimulating Factor Prior to Nonmyeloablative Irradiation Decreases Murine Host Hematopoietic Stem Cell Function and Increases Engraftment of Donor Marrow Cells by Barese, Cecilia, Pech, Nancy, Dirscherl, Sara, Meyers, Justin L., Sinn, Anthony L., Yoder, Mervin C., Goebel, W. Scott, Dinauer, Mary C.

“…The use of nonmyeloablative conditioning prior to bone marrow transplantation is an important component of transplantation‐based therapies for nonmalignant…”
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Gene therapy for chronic granulomatous disease by Barese, Cecilia N, Goebel, W Scott, Dinauer, Mary C

“…Chronic granulomatous disease (CGD) is a congenital immune deficiency that is a promising therapeutic target for gene replacement into haematopoietic stem…”
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FANCA safeguards interphase and mitosis during hematopoiesis in vivo by Abdul-Sater, Zahi, Cerabona, Donna, Potchanant, Elizabeth Sierra, Sun, Zejin, Enzor, Rikki, He, Ying, Robertson, Kent, Goebel, W. Scott, Nalepa, Grzegorz

“…The Fanconi anemia (FA/BRCA) signaling network controls multiple genome-housekeeping checkpoints, from interphase DNA repair to mitosis. The in vivo role of…”
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Enhanced Cutaneous Inflammatory Reactions to Aspergillus fumigatus in a Murine Model of Chronic Granulomatous Disease by Petersen, Jeffrey E., Hiran, Tejindervir S., Scott Goebel, W., Johnson, Christopher, Murphy, Robert C., Azmi, Farrukh H., Hood, Antoinette F., Travers, Jeffrey B., Dinauer, Mary C.

“…Chronic granulomatous disease is the manifestation of genetic defects of the leukocyte NADPH oxidase resulting in the absence of a respiratory burst. Patients…”
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Optimized cryopreservation method for human dental pulp-derived stem cells and their tissues of origin for banking and clinical use by Woods, Erik J., Perry, Brandon C., Hockema, J. Jeffrey, Larson, Lindsay, Zhou, Dan, Goebel, W. Scott

“…Dental pulp is a promising source of mesenchymal stem cells with the potential for cell-mediated therapies and tissue engineering applications. We recently…”
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Gene Correction Reduces Cutaneous Inflammation and Granuloma Formation in Murine X-Linked Chronic Granulomatous Disease by Scott Goebel, W., Mark, Lawrence A., Billings, Steven D., Meyers, Justin L., Pech, Nancy, Travers, Jeffrey B., Dinauer, Mary C.

“…Our laboratory previously demonstrated that X-linked chronic granulomatous disease (X-CGD) mice develop exaggerated inflammatory responses and form granulomas…”
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