Search Results - "Scott, V"

IS A NEW AND GENERAL THEORY OF MOLECULAR SYSTEMATICS EMERGING? by Edwards, Scott V.

“…The advent and maturation of algorithms for estimating species trees—phylogenetic trees that allow gene tree heterogeneity and whose tips represent lineages,…”
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Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery – An update by Jermain, Scott V., Brough, Chris, Williams, Robert O.

“…[Display omitted] Poor water-solubility remains a typical property of drug candidates in pharmaceutical development pipelines today. Various processes have…”
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Bioactive DNA from extracellular vesicles and particles by Malkin, Ethan Z., Bratman, Scott V.

“…Extracellular vesicles (EVs) and particles (EPs) have recently emerged as active carriers of molecular biomarkers and mediators of intercellular communication…”
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Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA by Shen, Shu Yi, Burgener, Justin M., Bratman, Scott V., De Carvalho, Daniel D.

“…Circulating cell-free DNA (cfDNA) comprises small DNA fragments derived from normal and tumor tissue that are released into the bloodstream. Recently,…”
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Resolving conflict in eutherian mammal phylogeny using phylogenomics and the multispecies coalescent model by Song, Sen, Liu, Liang, Edwards, Scott V., Wu, Shaoyuan

“…The reconstruction of the Tree of Life has relied almost entirely on concatenation methods, which do not accommodate gene tree heterogeneity, a property that…”
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A maximum pseudo-likelihood approach for estimating species trees under the coalescent model by Liu, Liang, Yu, Lili, Edwards, Scott V

“…Several phylogenetic approaches have been developed to estimate species trees from collections of gene trees. However, maximum likelihood approaches for…”
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Fitness consequences of structural variation inferred from a House Finch pangenome by Fang, Bohao, Edwards, Scott V.

“…Genomic structural variants (SVs) play a crucial role in adaptive evolution, yet their average fitness effects and characterization with pangenome tools are…”
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Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics by Rostami, Ariana, Lambie, Meghan, Yu, Caberry W., Stambolic, Vuk, Waldron, John N., Bratman, Scott V.

“…The kinetics of circulating cell-free DNA (cfDNA) release may provide a real-time assessment of induced cell death. However, there is a limited understanding…”
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Circulating tumor DNA and liquid biopsy in oncology by Cescon, David W, Bratman, Scott V, Chan, Steven M, Siu, Lillian L

“…Techniques for analyzing circulating tumor DNA (ctDNA) to detect, characterize and monitor cancer have matured rapidly. An increasing body of clinical evidence…”
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What Have We Learned from the First 500 Avian Genomes? by Bravo, Gustavo A, Schmitt, C. Jonathan, Edwards, Scott V

“…The increased capacity of DNA sequencing has significantly advanced our understanding of the phylogeny of birds and the proximate and ultimate mechanisms…”
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The prognostic landscape of genes and infiltrating immune cells across human cancers by Gentles, Andrew J, Newman, Aaron M, Liu, Chih Long, Bratman, Scott V, Feng, Weiguo, Kim, Dongkyoon, Nair, Viswam S, Xu, Yue, Khuong, Amanda, Hoang, Chuong D, Diehn, Maximilian, West, Robert B, Plevritis, Sylvia K, Alizadeh, Ash A

“…A searchable pan-cancer resource generated using data from nearly 18,000 human tumors reveals links between tumor infiltration by particular leukocyte subsets,…”
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Effects of the environment on the evolution of the vertebrate urinary tract by Wiener, Scott V.

“…Evolution of the vertebrate urinary system occurs in response to numerous selective pressures, which have been incompletely characterized. Developing research…”
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Evidence, causes, and consequences of declining nitrogen availability in terrestrial ecosystems by Mason, Rachel E, Craine, Joseph M, Lany, Nina K, Jonard, Mathieu, Ollinger, Scott V, Groffman, Peter M, Fulweiler, Robinson W, Angerer, Jay, Read, Quentin D, Reich, Peter B, Templer, Pamela H, Elmore, Andrew J

“…The productivity of ecosystems and their capacity to support life depends on access to reactive nitrogen (N). Over the past century, humans have more than…”
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Phylogenetics is the New Genetics (for Most of Biodiversity) by Smith, Stacey D., Pennell, Matthew W., Dunn, Casey W., Edwards, Scott V.

“…Despite substantial progress in understanding the genetic basis for differences in morphology, physiology, and behavior, many phenotypes of interest are…”
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Convergent regulatory evolution and loss of flight in paleognathous birds by Sackton, Timothy B, Grayson, Phil, Cloutier, Alison, Hu, Zhirui, Liu, Jun S, Wheeler, Nicole E, Gardner, Paul P, Clarke, Julia A, Baker, Allan J, Clamp, Michele, Edwards, Scott V

“…A core question in evolutionary biology is whether convergent phenotypic evolution is driven by convergent molecular changes in proteins or regulatory regions…”
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Disentangling the role of photosynthesis and stomatal conductance on rising forest water-use efficiency by Guerrieri, Rossella, Belmecheri, Soumaya, Ollinger, Scott V., Asbjornsen, Heidi, Jennings, Katie, Xiao, Jingfeng, Stocker, Benjamin D., Martin, Mary, Hollinger, David Y., Bracho-Garrillo, Rosvel, Clark, Kenneth, Dore, Sabina, Kolb, Thomas, Munger, J. William, Novick, Kimberly, Richardson, Andrew D.

“…Multiple lines of evidence suggest that plant water-use efficiency (WUE)—the ratio of carbon assimilation to water loss—has increased in recent decades…”
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Winter storms drive rapid phenotypic, regulatory, and genomic shifts in the green anole lizard by Campbell-Staton, Shane C., Cheviron, Zachary A., Rochette, Nicholas, Catchen, Julian, Losos, Jonathan B., Edwards, Scott V.

“…Extreme environmental perturbations offer opportunities to observe the effects of natural selection in wild populations. During the winter of 2013–2014, the…”
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The potential of genomics for restoring ecosystems and biodiversity by Breed, Martin F., Harrison, Peter A., Blyth, Colette, Byrne, Margaret, Gaget, Virginie, Gellie, Nicholas J. C., Groom, Scott V. C., Hodgson, Riley, Mills, Jacob G., Prowse, Thomas A. A., Steane, Dorothy A., Mohr, Jakki J.

“…Billions of hectares of natural ecosystems have been degraded through human actions. The global community has agreed on targets to halt and reverse these…”
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The Multispecies Coalescent Model Outperforms Concatenation Across Diverse Phylogenomic Data Sets by Jiang, Xiaodong, Edwards, Scott V., Liu, Liang

“…A statistical framework of model comparison and model validation is essential to resolving the debates over concatenation and coalescent models in phylogenomic…”
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Museum Genomics by Card, Daren C, Shapiro, Beth, Giribet, Gonzalo, Moritz, Craig, Edwards, Scott V

“…Natural history collections are invaluable repositories of biological information that provide an unrivaled record of Earth's biodiversity. Museum…”
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