Search Results - "Scott, Phillip M"

A USP28-53BP1-p53-p21 signaling axis arrests growth after centrosome loss or prolonged mitosis by Lambrus, Bramwell G, Daggubati, Vikas, Uetake, Yumi, Scott, Phillip M, Clutario, Kevin M, Sluder, Greenfield, Holland, Andrew J

“…Precise regulation of centrosome number is critical for accurate chromosome segregation and the maintenance of genomic integrity. In nontransformed cells,…”
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WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication by Park, Elizabeth M, Scott, Phillip M, Clutario, Kevin, Cassidy, Katelyn B, Zhan, Kevin, Gerber, Scott A, Holland, Andrew J

“…Centriole duplication occurs once in each cell cycle to maintain centrosome number. A previous genome-wide screen revealed that depletion of 14 RNA splicing…”
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Identification of the Functional Roles of Six Key Proteins in the Biosynthesis of Enterobacteriaceae Colanic Acid by Scott, Phillip M, Erickson, Katelyn M, Troutman, Jerry M

“…When subjected to harsh conditions such as low pH, pathogenic Escherichia coli can secrete colanic acid to establish a protective barrier between the organism…”
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Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer by Yeow, Zhong Y., Lambrus, Bramwell G., Marlow, Rebecca, Zhan, Kevin H., Durin, Mary-Anne, Evans, Lauren T., Scott, Phillip M., Phan, Thao, Park, Elizabeth, Ruiz, Lorena A., Moralli, Daniela, Knight, Eleanor G., Badder, Luned M., Novo, Daniela, Haider, Syed, Green, Catherine M., Tutt, Andrew N. J., Lord, Christopher J., Chapman, J. Ross, Holland, Andrew J.

“…Genomic instability is a hallmark of cancer, and has a central role in the initiation and development of breast cancer 1 , 2 . The success of poly-ADP ribose…”
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Tuning the Production of Variable Length, Fluorescent Polyisoprenoids Using Surfactant-Controlled Enzymatic Synthesis by Troutman, Jerry M, Erickson, Katelyn M, Scott, Phillip M, Hazel, Joseph M, Martinez, Christina D, Dodbele, Samantha

“…Bactoprenyl diphosphate (BPP), a two-E eight-Z configuration C55 isoprenoid, serves as a critical anchor for the biosynthesis of complex glycans central to…”
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The Metabolic, Hormonal, Biochemical, and Neuromuscular Function Responses to a Backward Sled Drag Training Session by West, Daniel J, Cunningham, Daniel J, Finn, Charlotte V, Scott, Phillip M, Crewther, Blair T, Cook, Christian J, Kilduff, Liam P

“…ABSTRACTWest, DJ, Cunningham, DJ, Finn, CV, Scott, PM, Crewther, BT, Cook, CJ, and Kilduff, LP. The metabolic, hormonal, biochemical, and neuromuscular…”
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Exploiting TRIM37-driven centrosome dysfunction to kill breast cancer cells by Yeow, Zhong Y., Lambrus, Bramwell G., Marlow, Rebecca, Zhan, Kevin H., Durin, Mary-Anne, Evans, Lauren T., Scott, Phillip M., Phan, Thao, Park, Elizabeth, Ruiz, Lorena A., Moralli, Daniela, Knight, Eleanor G., Badder, Luned M., Novo, Daniela, Haider, Syed, Green, Catherine M., Tutt, Andrew NJ, Lord, Christopher J, Chapman, J. Ross, Holland, Andrew J.

“…Genomic instability (GI) is a hallmark of cancer and plays a central role in breast cancer initiation and development 1 , 2 . The success of Poly-ADP ribose…”
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National Trends in Use of Computed Tomography in the Emergency Department by Kocher, Keith E., MD, MPH, Meurer, William J., MD, MS, Fazel, Reza, MD, MSc, Scott, Phillip A., MD, Krumholz, Harlan M., MD, SM, Nallamothu, Brahmajee K., MD, MPH

“…Study objective The role of computed tomography (CT) in acute illnesses has increased substantially in recent years; however, little is known about how CT use…”
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Prevention of emergency physician migratory contamination in a cluster randomized trial to increase tissue plasminogen activator use in stroke (the INSTINCT trial) by Weston, Victoria C., MD, Meurer, William J., MD, Frederiksen, Shirley M., MS, RN, Fox, Allison K., BA, Scott, Phillip A., MD

“…Abstract Objectives Cluster randomized trials (CRTs) are increasingly used to evaluate quality improvement interventions aimed at health care providers. In…”
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Protocol Deviations before and after Treatment with Intravenous Tissue Plasminogen Activator in Community Hospitals by Adelman, Eric E., MD, Scott, Phillip A., MD, Skolarus, Lesli E., MD, Fox, Allison K., MS, Frederiksen, Shirley M., MS, Meurer, William J., MD

“…Background Protocol deviations before and after tissue plasminogen activator (tPA) treatment for ischemic stroke are common. It is unclear if patient or…”
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An Emergency Department Intervention to Increase Warfarin Use for Atrial Fibrillation by Skolarus, Lesli E., MD, Morgenstern, Lewis B., MD, Scott, Phillip A., MD, Lisabeth, Lynda D., PhD, Murphy, Jillian B., MPH, Migda, Erin M., RN, BSN, Brown, Devin L., MD

“…Background Emergency department (ED) encounters represent lost opportunities to facilitate anticoagulation for stroke prevention in atrial fibrillation (AF)…”
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Enhancing Community Delivery of Tissue Plasminogen Activator in Stroke Through Community–Academic Collaborative Clinical Knowledge Translation by Scott, Phillip A., MD

“…Improving the clinical outcomes of stroke patients depends on the adoption of proven new therapies throughout the broader medical community. Approximately 1%…”
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Ultrastructural localization of radiolabelled L-dopa in the endocrine hypothalamus of the rat by Scott, D E, Scott, P M, Krobisch-Dudley, G

“…Light and electron microscopic autoradiography has been employed to define the neuroanatomical patterns of uptake and binding of radiolabelled L-dopa in the…”
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