Search Results - "Scott, MD"
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Cardiovascular Drug Development
Published in Journal of the American College of Cardiology (21-04-2015)“…Abstract Despite the global burden of cardiovascular disease, investment in cardiovascular drug development has stagnated over the past 2 decades, with…”
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2
The epidemiology of chronic kidney disease in sub-Saharan Africa: a systematic review and meta-analysis
Published in The Lancet global health (01-03-2014)“…Summary Background Amid rapid urbanisation, the HIV epidemic, and increasing rates of non-communicable diseases, people in sub-Saharan Africa are especially…”
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3
Time outside of therapeutic range in atrial fibrillation patients is associated with long-term risk of dementia
Published in Heart rhythm (01-12-2014)“…Background The mechanisms behind the association of atrial fibrillation (AF) and dementia are unknown. One possibility is that exposure to chronic…”
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4
Alloplastic reconstruction of the microtic ear
Published in Operative techniques in otolaryngology--head and neck surgery (01-06-2017)“…Alloplast microtia repair offers many advantages over autologous costal cartilage as a framework. Advantages include earlier reconstruction, fewer procedures,…”
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5
Transarterial Embolization of Symptomatic Focal Nodular Hyperplasia
Published in Journal of vascular and interventional radiology (01-11-2013)“…Abstract Purpose To evaluate the effectiveness of small size trisacryl gelatin microsphere embolization as a minimally invasive treatment option for patients…”
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Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial
Published in The Lancet (British edition) (24-01-2015)“…Summary Background Homozygous familial hypercholesterolaemia is a rare, serious disorder caused by very low or absent plasma clearance of LDL, substantially…”
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7
RadPath
Published in Academic radiology (2016)“…Rationale and Objectives The current paradigm of cancer diagnosis involves uncoordinated communication of findings from radiology and pathology to downstream…”
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8
Management of immune dysfunction after adult cardiac surgery
Published in The Journal of thoracic and cardiovascular surgery (01-09-2011)“…Objective Pulmonary dysfunction/multiorgan failure syndrome is an important cause of mortality and morbidity after cardiac operations. In this series, results…”
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Huge traumatic pulmonary artery pseudoaneurysm
Published in Radiology case reports (01-09-2017)“…Abstract Pulmonary artery pseudoaneurysm is a very rare complication of penetrating thoracic trauma. We present a case of a 27-year-old woman who developed a…”
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Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study
Published in The lancet oncology (01-01-2017)“…Summary Background Nivolumab has shown improved survival in the treatment of advanced non-small-cell lung cancer (NSCLC) previously treated with chemotherapy…”
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11
Medial Femoral Condyle Microvascular Bone Transfer as a Treatment for Capitate Avascular Necrosis: Surgical Technique and Case Report
Published in The Journal of hand surgery (American ed.) (01-10-2017)“…Avascular necrosis (AVN) of the capitate is a rare clinical entity for which a variety of treatment options have been described, ranging from immobilization to…”
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Anti-PCSK9 Antibody Effectively Lowers Cholesterol in Patients With Statin Intolerance
Published in Journal of the American College of Cardiology (17-06-2014)“…Objectives This study sought to evaluate the efficacy and safety of subcutaneous evolocumab compared with oral ezetimibe in hypercholesterolemic patients who…”
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Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 as monotherapy in patients with hypercholesterolaemia (MENDEL): a randomised, double-blind, placebo-controlled, phase 2 study
Published in The Lancet (British edition) (08-12-2012)“…Summary Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) increases serum LDL-cholesterol (LDL-C) concentrations. We assessed the effects of AMG…”
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14
PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial
Published in The Lancet (British edition) (24-01-2015)“…Summary Background Heterozygous familial hypercholesterolaemia is characterised by low cellular uptake of LDL cholesterol, increased plasma LDL cholesterol…”
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15
Rationale and design of the Further cardiovascular OUtcomes Research with PCSK9 Inhibition in subjects with Elevated Risk trial
Published in The American heart journal (01-03-2016)“…Background Despite current therapies, patients with vascular disease remain at high risk for major adverse cardiovascular events. Low-density lipoprotein…”
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16
Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): a randomised, placebo-controlled, dose-ranging, phase 2 study
Published in The Lancet (British edition) (08-12-2012)“…Summary Background LDL cholesterol (LDL-C) is a well established risk factor for cardiovascular disease. Proprotein convertase subtilisin/kexin type 9 (PCSK9)…”
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Risk of Bleeding after Native Renal Biopsy as a Function of Preprocedural Systolic and Diastolic Blood Pressure
Published in Journal of vascular and interventional radiology (01-02-2015)“…Abstract Purpose To determine the risk of bleeding complications after native renal biopsy as a function of preprocedural blood pressure (BP). Materials and…”
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18
Reduction in Lipoprotein(a) With PCSK9 Monoclonal Antibody Evolocumab (AMG 145)
Published in Journal of the American College of Cardiology (08-04-2014)“…Objectives The purpose of this study was assess the effect of evolocumab (AMG 145) on lipoprotein (Lp)(a) from a pooled analysis of 4 phase II trials…”
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Distal Ulnar Hounsfield Units Accurately Predict Bone Mineral Density and Future Fragility Fracture Risk
Published in The Journal of hand surgery (American ed.) (01-09-2016)Get full text
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What Happens to Serum Metal Ion Levels After a Metal-on-Metal Bearing is Removed?
Published in The Journal of arthroplasty (01-09-2013)“…Abstract Serum cobalt (Co) and chromium (Cr) levels are commonly used to screen for excessive wear of metal-on-metal hip replacements. However, it is unknown…”
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