Search Results - "Scott, L. W"
-
1
Comparative Analysis of Pharmacodynamics in the C3HeB/FeJ Mouse Tuberculosis Model for DprE1 Inhibitors TBA-7371, PBTZ169, and OPC-167832
Published in Antimicrobial agents and chemotherapy (18-10-2021)“…Multiple drug discovery initiatives for tuberculosis are currently ongoing to identify and develop new potent drugs with novel targets in order to shorten…”
Get full text
Journal Article -
2
Complications associated with central venous catheters. A survey
Published in Chest (01-12-1988)“…The Federal Food and Drug Administration has a system for reporting problems with medical devices that requires manufacturers of medical devices to report…”
Get more information
Journal Article -
3
Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model
Published in Antimicrobial agents and chemotherapy (15-11-2023)“…BTZ-043, a suicide inhibitor of the cell wall synthesis decaprenylphosphoryl-beta-D-ribose 2' epimerase, is under clinical development as a potential new…”
Get full text
Journal Article -
4
Effect of a low-fat diet on the incidence of actinic keratosis
Published in The New England journal of medicine (05-05-1994)“…Background. Actinic keratoses are premalignant lesions and are a sensitive and important manifestation of sun-induced skin damage. Studies in animals have…”
Get full text
Journal Article -
5
Analytical and biological evaluation of high throughput screen actives using evaporative light scattering, chemiluminescent nitrogen detection, and accurate mass LC-MS-MS
Published in Combinatorial chemistry & high throughput screening (01-09-2005)“…In this investigation the utility of evaporative light scattering detection (ELSD) combined with HPLC-MS was demonstrated as a key component of a…”
Get more information
Journal Article -
6
Inverse Relationship between Blood Levels of High Density Lipoprotein Subfraction 2 and Magnitude of Postprandial Lipemia
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1983)“…Triglyceridemic response to a standard oral fat meal was determined in 28 healthy subjects and related to the levels of several lipids, lipoproteins, and…”
Get full text
Journal Article -
7
Increased plasma concentration of cross-linked fibrin polymers in acute myocardial infarction
Published in Circulation (New York, N.Y.) (01-06-1987)“…Thrombin cleaves fibrinopeptides from fibrinogen, converting it to fibrin monomer, and activates factor XIII, which catalyzes the formation of intermolecular…”
Get full text
Journal Article -
8
General guidelines for a low-fat diet effective in the management and prevention of nonmelanoma skin cancer
Published in Nutrition and cancer (1997)“…A dietary intervention trial has shown a significant reduction in occurrence of actinic keratosis and non-melanoma skin cancer in skin cancer patients who…”
Get full text
Journal Article -
9
Central venous catheters. An overview of Food and Drug Administration activities
Published in Surgical oncology clinics of North America (01-07-1995)“…This article presents an overview of recent Food and Drug Administration issues pertaining to central venous catheters (CVCs) with emphasis on the CVC working…”
Get more information
Journal Article -
10
Protein conjugates of defined structure: Synthesis and use of a new carrier molecule
Published in Bioconjugate chemistry (01-11-1993)“…A new carrier molecule, NH2OCH2CO-(Gly)3-[Lys(H-Ser-)]5-Gly-OH, has been synthesized to facilitate the preparation of protein conjugates of defined structure…”
Get full text
Journal Article -
11
Plasma lipid and lipoprotein response of humans to beef fat, coconut oil and safflower oil
Published in The American journal of clinical nutrition (01-08-1985)“…This study's purpose was to evaluate the fasting human plasma lipid and lipoprotein responses to dietary beef fat (BF) by comparison with coconut oil (CO) and…”
Get full text
Journal Article -
12
Chemoimmunoconjugate development for ovarian carcinoma therapy: Preclinical studies with vinca alkaloid-monoclonal antibody constructs
Published in Bioconjugate chemistry (01-03-1993)“…Preclinical efficacy studies are presented in a human ovarian carcinoma model utilizing several novel conjugation strategies with the KS1/4 monoclonal antibody…”
Get full text
Journal Article -
13
-
14
National Cholesterol Education Program (NCEP): Highlights of the report of the expert panel on blood cholesterol levels in children and adolescents
Published in Pediatrics (Evanston) (01-03-1992)“…This article summarizes the NCEP Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents. It covers: 1) Significance of blood…”
Get full text
Journal Article -
15
Physician education in hyperlipidemia management : The impact on collaboration
Published in Southern medical journal (Birmingham, Ala.) (01-07-1997)“…Collaboration of health care professionals is likely beneficial in modifying patient behavior in the treatment of hyperlipidemia. The purpose of this study was…”
Get full text
Journal Article -
16
Evidence that a low-fat diet reduces the occurrence of non-melanoma skin cancer
Published in International journal of cancer (17-07-1995)“…The effect of a low-fat diet on occurrence of non-melanoma skin cancer was examined in a 2-year dietary intervention trial. A total of 101 skin-cancer patients…”
Get more information
Journal Article -
17
Induction of immunogenicity of monoclonal antibodies by conjugation with drugs
Published in Cancer research (Chicago, Ill.) (15-10-1991)“…Human anti-mouse antibody has been a nearly consistent result of human clinical trials utilizing murine antibodies. It is generally anticipated that the…”
Get full text
Journal Article -
18
Thiorphan and analogs: lack of correlation between potency to inhibit "enkephalinase A" in vitro and analgesic potency in vivo
Published in The Journal of pharmacology and experimental therapeutics (01-08-1985)“…The potencies of the R and S isomers of thiorphan and rigid analogs of thiorphan to produce analgesia in a mouse hot-plate assay have been compared with their…”
Get more information
Journal Article -
19
-
20
Total synthesis of (+-)-luciduline
Published in Journal of the American Chemical Society (01-06-1972)Get full text
Journal Article