Search Results - "Scott, L. Keith"

The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single-center experience by Keith, Philip D, Wells, Adam H, Hodges, Jeremy, Fast, Stephen H, Adams, Amber, Scott, L Keith

“…Sepsis remains a common condition with high mortality when multiple organ failure develops. The evidence for therapeutic plasma exchange (TPE) in this setting…”
Get full text

The successful use of therapeutic plasma exchange for severe COVID-19 acute respiratory distress syndrome with multiple organ failure by Keith, Philip, Day, Matthew, Choe, Carol, Perkins, Linda, Moyer, Lou, Hays, Erin, French, Marshall, Hewitt, Kristi, Gravel, Gretchen, Guffey, Amanda, Scott, L Keith

“…The COVID-19 pandemic has brought about an urgent need for effective treatment, while conserving vital resources such as intensive care unit beds and…”
Get full text

Characterization of Peripheral Circadian Clocks in Adipose Tissues by ZVONIC, Sanjin, PTITSYN, Andrey A, CONRAD, Steven A, SCOTT, L. Keith, FLOYD, Z. Elizabeth, KILROY, Gail, XIYING WU, GOH, Brian C, MYNATT, Randall L, GIMBLE, Jeffrey M

“…Characterization of Peripheral Circadian Clocks in Adipose Tissues Sanjin Zvonic 1 , Andrey A. Ptitsyn 2 , Steven A. Conrad 3 , L. Keith Scott 3 , Z. Elizabeth…”
Get full text

Unprovoked serotonin syndrome-like presentation of SARS-CoV-2 infection: A small case series by Keith, Philip, Saint-Jour, Marc, Pusey, Frank, Hodges, Jeremy, Jalali, Farid, Scott, L Keith

“…Clinicians and researchers have reported an array of neurological abnormalities in coronavirus disease 2019 (COVID-19), and while serotonin excess has been…”
Get full text

Yield and characterization of subcutaneous human adipose-derived stem cells by flow cytometric and adipogenic mRNA analyzes by Yu, Gang, Wu, Xiying, Dietrich, Marilyn A, Polk, Paula, Scott, L. Keith, Ptitsyn, Andrey A, Gimble, Jeffrey M

“…Abstract Background aims Adipose-derived stromal/stem cells (ASC) capable of multipotential differentiation can be isolated with high yields from human…”
Get full text

Circadian clocks are resounding in peripheral tissues by Ptitsyn, Andrey A, Zvonic, Sanjin, Conrad, Steven A, Scott, L Keith, Mynatt, Randall L, Gimble, Jeffrey M

“…Circadian rhythms are prevalent in most organisms. Even the smallest disturbances in the orchestration of circadian gene expression patterns among different…”
Get full text

Penetrating thoracic injury requiring emergency pneumonectomy supported with two ECMO runs: A testament to multidisciplinary critical care medicine by Dotiwala, Aryeneesh, Kalakoti, Piyush, Grier, Laurie R., Quispe, Marco, Scott, L. Keith, Conrad, Steven A., Samra, Navdeep S.

“…Post-traumatic pneumonectomies are uncommon and, if necessary, carry significant mortality. The use of extracorporeal membrane oxygenation (ECMO) for lung…”
Get full text

Circadian Oscillation of Gene Expression in Murine Calvarial Bone by Zvonic, Sanjin, Ptitsyn, Andrey A, Kilroy, Gail, Wu, Xiying, Conrad, Steven A, Scott, L Keith, Guilak, Farshid, Pelled, Gadi, Gazit, Dan, Gimble, Jeffrey M

“…The genes encoding the core circadian transcription factors display an oscillating expression profile in murine calvarial bone. More than 26% of the calvarial…”
Get full text

Continuous Renal Replacement Therapies: A Brief Primer for the Neurointensivist by Patel, Pritesh, Nandwani, Veena, McCarthy, Paul J., Conrad, Steven A., Keith Scott, L.

“…Continuous renal replacement therapy (CRRT) is a renal replacement modality that is often used in the ICU setting, including the neuro-ICU. This form of renal…”
Get full text

Angiopoietins as promising biomarkers and potential therapeutic targets in brain injury by Chittiboina, Prashant, Ganta, Vijay, Monceaux, Christopher P., Scott, L. Keith, Nanda, Anil, Alexander, J. Steven

“…Traumatic brain injury (TBI) and sub-arachnoid hemorrhage (SAH) are major causes of long-term disability, mortality, and enormous economic costs to society…”
Get full text

Physiologic Improvement in Respiratory Acidosis Using Extracorporeal Co2 Removal With Hemolung Respiratory Assist System in the Management of Severe Respiratory Failure From Coronavirus Disease 2019 by Akkanti, Bindu, Jagpal, Sugeet, Darwish, Ribal, Saavedra Romero, Ramiro, Scott, L Keith, Dinh, Kha, Hussain, Sabiha, Radbel, Jared, Saad, Mohamed A, Enfield, Kyle B, Conrad, Steven A

“…OBJECTIVESAbout 15% of hospitalized coronavirus disease 2019 patients require ICU admission, and most (80%) of these require invasive mechanical ventilation…”
Get full text

Percutaneous Cannulation for Extracorporeal Membrane Oxygenation by Intensivists: A Retrospective Single-Institution Case Series by Conrad, Steven A, Grier, Laurie R, Scott, L Keith, Green, Rebecca, Jordan, Mary

“…OBJECTIVE:Extracorporeal membrane oxygenation provides support for patients with severe acute cardiopulmonary failure, allowing the application of lung or…”
Get full text

Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis by Kuklin, Vladimir, Sovershaev, Michael, Bjerner, Johan, Keith, Philip, Scott, L Keith, Thomas, Owen Matthew Truscott, Szpirt, Wladimir, Rock, Gail, Stegmayr, Bernd

“…The impact of therapeutic plasma exchange (TPE) on short-term mortality in adult patients with sepsis-induced organ dysfunction remains uncertain. The…”
Get full text

Obesity Exacerbates Sepsis-Induced Inflammation and Microvascular Dysfunction in Mouse Brain by VACHHARAJANI1, VIDULA, RUSSELL2, JANICE M., SCOTT1, KEITH L., CONRAD1, STEVEN, STOKES2, KAREN Y., TALLAM3, LAKSHMI, HALL3, JOHN, GRANGER2, D. NEIL

“…Objective: Obese patients with sepsis have higher morbidity and mortality than lean counterparts, but the mechanisms involved are unknown. The authors examined…”
Get full text

High-Frequency Oscillatory Ventilation for Refractory Hypoxemia in Severe COVID-19 Pneumonia: A Small Case Series by Keith, Philip, Scott, L Keith, Perkins, Linda, Burnside, Rebecca, Day, Matthew

“…BACKGROUND COVID-19 continues to place a tremendous burden on the healthcare system, with most deaths resulting from respiratory failure. Management strategies…”
Get full text

Clinically Promising Biomarkers in Cystic Fibrosis Pulmonary Exacerbations by Scott, L. Keith, Toner, Robert

“…Cystic fibrosis is a complex genetic disease hallmarked by repetitive infectious exacerbations that leads to destruction of airway architecture, acute on…”
Get full text

Back to the Future: A Case of Severe ARDS Responsive to Shunned Therapies, A Review of the Past, and a Road Map to Future Investigations by Keith, Philip, Choe, Carol, Rikard, Ben, Stoudemire, Kari, Guffey, Amanda, Scott, L. Keith

“…Background The COVID-19 pandemic served as a reminder of the limited treatments available for acute respiratory distress syndrome (ARDS). The pandemic has…”
Get full text

Improved survival in COVID‐19 related sepsis and ARDS treated with a unique “triple therapy” including therapeutic plasma exchange: A single center retrospective analysis by Keith, Philip, Bohn, Rebecca Inez Caldino, Nguyen, Trung, Scott, L. Keith, Richmond, Monty, Day, Matthew, Choe, Carol, Perkins, Linda, Burnside, Rebecca, Pyke, Richard, Rikard, Ben, Guffey, Amanda, Saini, Arun, Park, H. J., Carcillo, Joseph

“…Background Throughout the COVID‐19 pandemic, the mortality of critically ill patients remained high. Our group developed a treatment regimen targeting sepsis…”
Get full text

Use of therapeutic plasma exchange as a rescue therapy in 2009 pH1N1 influenza A--an associated respiratory failure and hemodynamic shock by Patel, Pritesh, Nandwani, Veena, Vanchiere, John, Conrad, Steven A, Scott, L Keith

“…Acute pneumonitis with acute lung injury is a cause of significant mortality related to the 2009 pH1N1 influenza A virus. Widespread lung inflammation and…”
Get full text

Extracorporeal Carbon Dioxide Removal in the Management of Complex Bilateral Flail Chest Injury by Wells, Adam H, Oswald, Todd J, Samra, Navdeep, Scott, L Keith, Conrad, Steven A

“…Flail chest is an uncommon consequence of traumatic injury. Medical management includes mechanical ventilation for internal pneumatic stabilization. Control of…”
Get full text