Search Results - "Scott, Kevin A"

New Class of Anion-Accelerated Amino-Cope Rearrangements as Gateway to Diverse Chiral Structures by Chogii, Isaac, Das, Pradipta, Fell, Jason S, Scott, Kevin A, Crawford, Mark N, Houk, K. N, Njardarson, Jon T

“…We report useful new lithium-assisted asymmetric anion-accelerated amino-Cope rearrangement cascades. A strategic nitrogen atom chiral auxiliary serves three…”
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Analysis of US FDA-Approved Drugs Containing Sulfur Atoms by Scott, Kevin A., Njardarson, Jon T.

“…In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis…”
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Phenols in Pharmaceuticals: Analysis of a Recurring Motif by Scott, Kevin A., Cox, Philip B., Njardarson, Jon T.

“…Phenols and phenolic ethers are significant scaffolds recurring both in nature and among approved small-molecule pharmaceuticals. This compendium presents the…”
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Dienolate Annulation Approach for Assembly of Densely Substituted Aromatic Architectures by Scott, Kevin A, Groch, Jeffrey R, Chogii, Isaac, Delost, Michael D, Das, Pradipta, Njardarson, Jon T

“…The efficient assembly of complex aromatic structures from simple acyclic building blocks is reported. An anion-cascade union of an enoate and a conjugated…”
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A Structural Analysis of the FDA Green Book-Approved Veterinary Drugs and Roles in Human Medicine by Scott, Kevin A, Qureshi, M. Haziq, Cox, Philip B, Marshall, Christopher M, Bellaire, Bailey C, Wilcox, Michael, Stuart, Bradey A. R, Njardarson, Jon T

“…The FDA Green Book is a list of all drug products that have been approved by the FDA for use in veterinary medicine. The Green Book, as published, lacks…”
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Chemistry Departments Should Facilitate Graduate-Level Second-Language Writing Instruction by Shufflebarger, Amanda M, Scott, Kevin A

“…Though writing is an important part of chemists’ careers inside and outside of academia, graduate-level chemistry programs often do not teach academic writing…”
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Lessons in Stereochemistry: Resolution, Synthesis, and Characterization of Chiral Compounds by Scott, Kevin A, Marciniak, Alexander, Benson, William G, Polt, Robin

“…This modular, open-framework capstone course delves deeply into the synthesis, separation, and characterization of chiral molecules while teaching critical…”
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Protein State‐Dependent Chemical Biology by Scott, Kevin A., Zhang, Tiffany L., Xi, Sarah Y., Ngo, Bryan, Vinogradova, Ekaterina V.

“…Chemical methods that provide a readout of biochemical changes within a cell at the protein level enable precise characterization of biological phenotypes that…”
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Correction to “New Class of Anion-Accelerated Amino-Cope Rearrangements as Gateway to Diverse Chiral Structures” by Chogii, Isaac, Das, Pradipta, Fell, Jason S, Scott, Kevin A, Crawford, Mark N, Houk, K. N, Njardarson, Jon T

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Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans by Mood, Aaron D., Premachandra, Ilandari Dewage Udara Anulal, Hiew, Stanley, Wang, Fuqiang, Scott, Kevin A., Oldenhuis, Nathan J., Liu, Haoping, Van Vranken, David L.

“…Four phthalazinones (CIDs 22334057, 22333974, 22334032, 22334012) and one isoquinolone (CID 5224943) were previously shown to be potent enhancers of antifungal…”
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Subcellular Protein Localization by Using a Genetically Encoded Fluorescent Amino Acid by Charbon, Godefroid, Brustad, Eric, Scott, Kevin A., Wang, Jiangyun, Løbner-Olesen, Anders, Schultz, Peter G., Jacobs-Wagner, Christine, Chapman, Eli

“…CouAA‐lescence: A fluorescent amino acid (CouAA) was site‐specifically incorporated into FtsZ, the bacterial tubulin homologue, in living cells. FtsZCouAA is…”
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Potent Synergy between Spirocyclic Pyrrolidinoindolinones and Fluconazole against Candida albicans by Premachandra, Ilandari Dewage Udara Anulal, Scott, Kevin A., Shen, Chengtian, Wang, Fuqiang, Lane, Shelley, Liu, Haoping, Van Vranken, David L.

“…A spiroindolinone,…”
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Minimalistic graphical presentation approach for total syntheses by Scott, Kevin A., Groch, Jeffrey R., Bao, Jianhua, Marshall, Christopher M., Allen, Rachel A., Nick, Steven J., Lauta, Nicholas R., Williams, Ryan E., Qureshi, Munaum H., Delost, Michael D., Njardarson, Jon T.

“…We report a single image minimalistic presentation format for total syntheses, wherein on the foundation of a color-coded synthetic step/complexity chart are…”
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Microarray Analysis of Drosophila Development During Metamorphosis by White, Kevin P., Rifkin, Scott A., Hurban, Patrick, Hogness, David S.

“…Metamorphosis is an integrated set of developmental processes controlled by a transcriptional hierarchy that coordinates the action of hundreds of genes. In…”
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Analysis of FDA-Approved Drugs and Select Methods toward Analogs of Cantharidin and Apomorphine by Scott, Kevin A

“…Small molecule natural products are valuable in medicine both as pharmaceutical agents and as starting points for development of pharmaceutical agents. The…”
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Judicial Behavior and the Rehnquist Court's Federalism Revolution by Scott, Kevin M.

“…Attempts to demonstrate that law systematically influences the behavior of the justices of the Supreme Court have traditionally foundered on the inability to…”
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HPLC DETERMINATION OF TRITIATED POLYCYCLIC AROMATIC HYDROCARBON METABOLITES IN THE SUBFEMTOMOLE RANGE by G. Scott, Gary, A. Stephens, John, D. Rohrbacher, Kevin, R. Thornton-Manning, Janice, Gerde, Per, R. Dahl, Alan

“…In experiments to determine the toxicokinetics of polycyclic aromatic hydrocarbons (PAHs) in lungs at environmentally realistic levels, a technique to measure…”
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Association study of chromosome 4 STRs polymorphisms with nasopharyngeal carcinoma by Guo, Xiu-Chan, O'Brien, Stephen J, Winkler, Cheryl, Scott, Kevin, Hutcheson, Holli, David, Victor, Kessing, Bailey, Zheng, Yu-Ming, Liao, Jian, Lui, Yan, Guy, de The, Zeng, Yi

“…Nasopharyngeal carcinoma (NPC) is a complex disease caused by an interaction of EBV chronic infection, environment and host genes, in a multi-step process of…”
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