Search Results - "Scott, Joseph W."

Extremophile enzyme activity lab: using catalase from Pyrobaculum calidifontis to highlight temperature sensitivity and thermostable enzyme activity by Scott, Joseph W, Steel, J Jordan

“…There are places on earth that are considered to possess extreme physico-chemical characteristics as they relate to life. Surprisingly, there are microbes that…”
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Novel Multiprotein Complexes Identified in the Hyperthermophilic Archaeon Pyrococcus furiosus by Non-denaturing Fractionation of the Native Proteome by Menon, Angeli Lal, Poole, 2nd, Farris L, Cvetkovic, Aleksandar, Trauger, Sunia A, Kalisiak, Ewa, Scott, Joseph W, Shanmukh, Saratchandra, Praissman, Jeremy, Jenney, Jr, Francis E, Wikoff, William R, Apon, John V, Siuzdak, Gary, Adams, Michael W W

“…Virtually all cellular processes are carried out by dynamic molecular assemblies or multiprotein complexes, the compositions of which are largely undefined…”
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Characterization of Ten Heterotetrameric NDP-Dependent Acyl-CoA Synthetases of the Hyperthermophilic Archaeon Pyrococcus furiosus by Scott, Joseph W., Adams, Michael W. W., Poole, Farris L.

“…The hyperthermophilic archaeon Pyrococcus furiosus grows by fermenting peptides and carbohydrates to organic acids. In the terminal step, acyl-CoA synthetase…”
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A computational framework for proteome-wide pursuit and prediction of metalloproteins using ICP-MS and MS/MS data by Lancaster, W Andrew, Praissman, Jeremy L, Poole, 2nd, Farris L, Cvetkovic, Aleksandar, Menon, Angeli Lal, Scott, Joseph W, Jenney, Jr, Francis E, Thorgersen, Michael P, Kalisiak, Ewa, Apon, Junefredo V, Trauger, Sunia A, Siuzdak, Gary, Tainer, John A, Adams, Michael W W

“…Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze…”
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Identification of Putative Agouti-Related Protein(87−132)-Melanocortin-4 Receptor Interactions by Homology Molecular Modeling and Validation Using Chimeric Peptide Ligands by Wilczynski, Andrzej, Wang, Xiang S, Joseph, Christine G, Xiang, Zhimin, Bauzo, Rayna M, Scott, Joseph W, Sorensen, Nicholas B, Shaw, Amanda M, Millard, William J, Richards, Nigel G, Haskell-Luevano, Carrie

“…Agouti-related protein (AGRP) is one of only two naturally known antagonists of G-protein-coupled receptors (GPCRs) identified to date. Specifically, AGRP…”
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Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS) by Adams, Michael W W, Tainer, John A, Hura, Greg L, Menon, Angeli L, Hammel, Michal, Rambo, Robert P, Poole II, Farris L, Tsutakawa, Susan E, Jenney Jr, Francis E, Classen, Scott, Frankel, Kenneth A, Hopkins, Robert C, Yang, Sung-jae, Scott, Joseph W, Dillard, Bret D

“…High-throughput analyses of macromolecular shape and oligomeric state at ∼15 Å resolution are possible with a partially automated small angle X-ray scattering…”
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Microbial metalloproteomes are largely uncharacterized by Adams, Michael W. W, Cvetkovic, Aleksandar, Menon, Angeli Lal, Thorgersen, Michael P, Scott, Joseph W, Poole II, Farris L, Jenney Jr, Francis E, Lancaster, W. Andrew, Praissman, Jeremy L, Shanmukh, Saratchandra, Vaccaro, Brian J, Trauger, Sunia A, Kalisiak, Ewa, Apon, Junefredo V, Siuzdak, Gary, Yannone, Steven M, Tainer, John A

“…Metal ion cofactors afford proteins virtually unlimited catalytic potential, enable electron transfer reactions and have a great impact on protein stability…”
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Purification, Overproduction, and Partial Characterization of β-RFAP Synthase, a Key Enzyme in the Methanopterin Biosynthesis Pathway by Scott, Joseph W, Rasche, Madeline E

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structure−Activity Relationships of the Unique and Potent Agouti-Related Protein (AGRP)−Melanocortin Chimeric Tyr-c[β-Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 Peptide Template by Wilczynski, Andrzej, Wilson, Krista R, Scott, Joseph W, Edison, Arthur S, Haskell-Luevano, Carrie

“…The melanocortin receptor system consists of endogenous agonists, antagonists, G-protein coupled receptors, and auxiliary proteins that are involved in the…”
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Discovery of Melanocortin Ligands via a Double Simultaneous Substitution Strategy Based on the Ac-His‑dPhe-Arg-Trp-NH2 Template by Todorovic, Aleksandar, Lensing, Cody J, Holder, Jerry Ryan, Scott, Joseph W, Sorensen, Nicholas B, Haskell-Luevano, Carrie

“…The melanocortin system regulates an array of diverse physiological functions including pigmentation, feeding behavior, energy homeostasis, cardiovascular…”
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γ₂-Melanocyte stimulation hormone (γ₂-MSH) truncation studies results in the cautionary note that γ₂-MSH is not selective for the mouse MC3R over the mouse MC5R by Joseph, Christine G, Yao, Hua, Scott, Joseph W, Sorensen, Nicholas B, Marnane, Rebecca N, Mountjoy, Kathleen G, Haskell-Luevano, Carrie

“…The melanocortin system has been implicated in a multitude of physiological pathways including obesity, satiety, energy homeostasis, sexual behavior,…”
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Stereochemical Studies of the Monocyclic Agouti-Related Protein (103−122) Arg-Phe-Phe Residues:  Conversion of a Melanocortin-4 Receptor Antagonist into an Agonist and Results in the Discovery of a Potent and Selective Melanocortin-1 Agonist by Joseph, Christine G, Wang, Xiang S, Scott, Joseph W, Bauzo, Rayna M, Xiang, Zhimin, Richards, Nigel G, Haskell-Luevano, Carrie

“…The agouti-related protein (AGRP) is an endogenous antagonist of the centrally expressed melanocortin receptors. The melanocortin-4 receptor (MC4R) is involved…”
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Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity by Joseph, Christine G., Wilczynski, Andrzej, Holder, Jerry R., Xiang, Zhimin, Bauzo, Rayna M., Scott, Joseph W., Haskell-Luevano, Carrie

“…Agouti-related protein (AGRP) is one of only two known endogenous antagonists of G-protein coupled receptors (GPCRs). Specifically, AGRP antagonizes the brain…”
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Discovery of Melanocortin Ligands via a Double Simultaneous Substitution Strategy Based on the Ac-His- d Phe-Arg-Trp-NH 2 Template by Todorovic, Aleksandar, Lensing, Cody J., Holder, Jerry Ryan, Scott, Joseph W., Sorensen, Nicholas B., Haskell-Luevano, Carrie

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Discovery of Melanocortin Ligands via a Double Simultaneous Substitution Strategy Based on the Ac-His-dPhe-Arg-Trp-NH 2 Template by Todorovic, Aleksandar, Lensing, Cody J, Holder, Jerry Ryan, Scott, Joseph W, Sorensen, Nicholas B, Haskell-Luevano, Carrie

“…The melanocortin system regulates an array of diverse physiological functions including pigmentation, feeding behavior, energy homeostasis, cardiovascular…”
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gamma sub(2)-Melanocyte stimulation hormone ( gamma sub(2)-MSH) truncation studies results in the cautionary note that gamma sub(2)-MSH is not selective for the mouse MC3R over the mouse MC5R by Joseph, Christine G, Yao, Hua, Scott, Joseph W, Sorensen, Nicholas B, Marnane, Rebecca N, Mountjoy, Kathleen G, Haskell-Luevano, Carrie

“…The melanocortin system has been implicated in a multitude of physiological pathways including obesity, satiety, energy homeostasis, sexual behavior,…”
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Gamma2-Melanocyte Stimulation Hormone (γ2-MSH) Truncation Studies Results in the Cautionary Note that γ2-MSH is Not Selective for the Mouse MC3R over the Mouse MC5R by Joseph, Christine G., Yao, Hua, Scott, Joseph W., Sorensen, Nicholas B., Marnane, Rebecca N., Mountjoy, Kathleen G., Haskell-Luevano, Carrie

“…The melanocortin system has been implicated in a multitude of physiological pathways including obesity, satiety, energy homeostasis, sexual behavior,…”
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γ 2-Melanocyte stimulation hormone (γ 2-MSH) truncation studies results in the cautionary note that γ 2-MSH is not selective for the mouse MC3R over the mouse MC5R by Joseph, Christine G., Yao, Hua, Scott, Joseph W., Sorensen, Nicholas B., Marnane, Rebecca N., Mountjoy, Kathleen G., Haskell-Luevano, Carrie

“…[Display omitted] ▶ Identification of γ 2-MSH peptide amino acids important for melanocortin receptor potency. ▶ The γ 2-MSH ligands have different mouse…”
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γ2-Melanocyte stimulation hormone γ2-MSH truncation studies results in the cautionary note that γ2-MSH is not selective for the mouse MC3R over the mouse MC5R by JOSEPH, Christine G, HUA YAO, SCOTT, Joseph W, SORENSEN, Nicholas B, MARNANE, Rebecca N, MOUNTJOY, Kathleen G, HASKELL-LUEVANO, Carrie

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Reprise: Conceptualizing and researching American polygyny?And critics answered by Scott, Joseph W.

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