Search Results - "Scott, J. Anthony G"

Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study by Scott, J Anthony G, Dr, Berkley, James A, MD, Mwangi, Isaiah, MMed, Ochola, Lucy, PhD, Uyoga, Sophie, MSc, Macharia, Alexander, MSc, Ndila, Carolyne, MSc, Lowe, Brett S, MPhil, Mwarumba, Salim, MSc, Bauni, Evasius, PhD, Marsh, Kevin, FRCP, Williams, Thomas N, MRCP

“…Summary Background Many investigators have suggested that malaria infection predisposes individuals to bacteraemia. We tested this hypothesis with mendelian…”
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Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis by Nair, Harish, Dr, Simões, Eric AF, Prof, Rudan, Igor, Prof, Gessner, Bradford D, MD, Azziz-Baumgartner, Eduardo, MD, Zhang, Jian Shayne F, MPH, Feikin, Daniel R, MD, Mackenzie, Grant A, PhD, Moiïsi, Jennifer C, PhD, Roca, Anna, PhD, Baggett, Henry C, MD, Zaman, Syed MA, PhD, Singleton, Rosalyn J, MD, Lucero, Marilla G, MD, Chandran, Aruna, MD, Gentile, Angela, Prof, Cohen, Cheryl, MBBCH, Krishnan, Anand, MD, Bhutta, Zulfiqar A, Prof, Arguedas, Adriano, Prof, Clara, Alexey Wilfrido, MPH, Andrade, Ana Lucia, Prof, Ope, Maurice, MBChB, Ruvinsky, Raúl Oscar, Prof, Hortal, María, Prof, McCracken, John P, ScD, Madhi, Shabir A, Prof, Bruce, Nigel, Prof, Qazi, Shamim A, MD, Morris, Saul S, PhD, El Arifeen, Shams, DrPH, Weber, Martin W, MD, Scott, J Anthony G, Prof, Brooks, W Abdullah, MD, Breiman, Robert F, MD, Campbell, Harry, Prof

“…Summary Background The annual number of hospital admissions and in-hospital deaths due to severe acute lower respiratory infections (ALRI) in young children…”
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Use of vaccines as probes to define disease burden by Feikin, Daniel R, Dr, Scott, J Anthony G, Prof, Gessner, Bradford D, MD

“…Summary Vaccine probe studies have emerged in the past 15 years as a useful way to characterise disease. By contrast, traditional studies of vaccines focus on…”
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The prevalence and risk factors for pneumococcal colonization of the nasopharynx among children in Kilifi District, Kenya by Abdullahi, Osman, Karani, Angela, Tigoi, Caroline C, Mugo, Daisy, Kungu, Stella, Wanjiru, Eva, Jomo, Jane, Musyimi, Robert, Lipsitch, Marc, Scott, J Anthony G

“…Pneumococcal conjugate vaccines (PCV) reduce nasopharyngeal carriage of vaccine-serotype pneumococci but increase in the carriage of non-vaccine serotypes. We…”
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The impact of introduction of the 10-valent pneumococcal conjugate vaccine on pneumococcal carriage in Nigeria by Adamu, Aishatu L., Ojal, J., Abubakar, Isa A., Odeyemi, Kofo A., Bello, Musa M., Okoromah, Christy A. N., Karia, Boniface, Karani, Angela, Akech, Donald, Inem, Victor, Scott, J. Anthony G., Adetifa, Ifedayo M. O.

“…Pneumococcal conjugate vaccines (PCVs) protect against invasive pneumococcal disease (IPD) among vaccinees. However, at population level, this protection is…”
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defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus by Willcocks, Lisa C, Carr, Edward J, Niederer, Heather A, Rayner, Tim F, Williams, Thomas N, Yang, Wanling, Scott, J. Anthony G, Urban, Britta C, Peshu, Norbert, Vyse, Timothy J, Lau, Yu Lung, Lyons, Paul A, Smith, Kenneth G.C

“…Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease more prevalent in people of African and Asian origin than Caucasian origin. FcγRIIb is…”
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The epidemiology of fecal carriage of nontyphoidal Salmonella among healthy children and adults in three sites in Kenya by Muthumbi, Esther M, Mwanzu, Alfred, Mbae, Cecilia, Bigogo, Godfrey, Karani, Angela, Mwarumba, Salim, Verani, Jennifer R, Kariuki, Samuel, Scott, J Anthony G

“…Despite the importance of non-Typhoidal Salmonella (NTS) disease in Africa, epidemiologic data on carriage and transmission are few. These data are important…”
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The Descriptive Epidemiology of Streptococcus pneumoniae and Haemophilus influenzae Nasopharyngeal Carriage in Children and Adults in Kilifi District, Kenya by Abdullahi, Osman, Nyiro, Joyce, Lewa, Pole, Slack, Mary, Scott, J Anthony G

“…BACKGROUND:Transmission and nasopharyngeal colonization are necessary steps en route to invasive pneumococcal or Haemophilus influenzae disease but their…”
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Nasopharyngeal Pneumococcal Carriage in Nigeria: a two-site, population-based survey by Adetifa, Ifedayo M. O., Adamu, Aishatu L., Karani, Angela, Waithaka, Michael, Odeyemi, Kofo A., Okoromah, Christy A. N., Bello, Mohammed M., Abubakar, Isa S., Inem, Victor, Scott, J. Anthony. G.

“…Changes in nasopharyngeal (NP) carriage of vaccine-type (VT) Streptococcus pneumoniae can be used to assess the effectiveness of a pneumococcal conjugate…”
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The indirect health effects of malaria estimated from health advantages of the sickle cell trait by Uyoga, Sophie, Macharia, Alex W., Ndila, Carolyne M., Nyutu, Gideon, Shebe, Mohammed, Awuondo, Kennedy O., Mturi, Neema, Peshu, Norbert, Tsofa, Benjamin, Scott, J. Anthony G., Maitland, Kathryn, Williams, Thomas N.

“…Most estimates of the burden of malaria are based on its direct impacts; however, its true burden is likely to be greater because of its wider effects on…”
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Invasive Group A Streptococcus Infection among Children, Rural Kenya by Seale, Anna C, Davies, Mark R, Anampiu, Kirimi, Morpeth, Susan C, Nyongesa, Sammy, Mwarumba, Salim, Smeesters, Pierre R, Efstratiou, Androulla, Karugutu, Rosylene, Mturi, Neema, Williams, Thomas N, Scott, J Anthony G, Kariuki, Samuel, Dougan, Gordon, Berkley, James A

“…To determine the extent of group A Streptococcus (GAS) infections in sub-Saharan Africa and the serotypes that cause disease, we analyzed surveillance data for…”
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Changing use of surgical antibiotic prophylaxis in Thika Hospital, Kenya: a quality improvement intervention with an interrupted time series design by Aiken, Alexander M, Wanyoro, Anthony K, Mwangi, Jonah, Juma, Francis, Mugoya, Isaac K, Scott, J Anthony G

“…In low-income countries, Surgical Site Infection (SSI) is a common form of hospital-acquired infection. Antibiotic prophylaxis is an effective method of…”
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Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case–control study by Williams, Thomas N, Dr, Uyoga, Sophie, MSc, Macharia, Alex, MSc, Ndila, Carolyne, MSc, McAuley, Charlotte F, MRCPCH, Opi, Daniel H, MRes, Mwarumba, Salim, HND, Makani, Julie, MRCP, Komba, Albert, MPH, Ndiritu, Moses N, MPhil, Sharif, Shahnaaz K, MD, Marsh, Kevin, FRCP, Berkley, James A, MD, Scott, J Anthony G, FRCP

“…Summary Background In sub-Saharan Africa, more than 90% of children with sickle-cell anaemia die before the diagnosis can be made. The causes of death are…”
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Population effect of 10-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae and non-typeable Haemophilus influenzae in Kilifi, Kenya: findings from cross-sectional carriage studies by Hammitt, Laura L, Dr, Akech, Donald O, BSc, Morpeth, Susan C, FRACP, Karani, Angela, BSc, Kihuha, Norbert, BSc, Nyongesa, Sammy, MSc, Bwanaali, Tahreni, MBA, Mumbo, Edward, BSc, Kamau, Tatu, MPH, Sharif, Shahnaaz K, MD, Scott, J Anthony G, Prof

“…Summary Background The effect of 7-valent pneumococcal conjugate vaccine (PCV) in developed countries was enhanced by indirect protection of unvaccinated…”
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Rates of Acquisition and Clearance of Pneumococcal Serotypes in the Nasopharynges of Children in Kilifi District, Kenya by Abdullahi, Osman, Karani, Angela, Tigoi, Caroline C., Mugo, Daisy, Kungu, Stella, Wanjiru, Eva, Jomo, Jane, Musyimi, Robert, Lipsitch, Marc, Scott, J. Anthony G.

“…Background. To understand and model the impact of pneumococcal conjugate vaccines at the population level, we need to know the transmission dynamics of…”
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Risk and causes of paediatric hospital-acquired bacteraemia in Kilifi District Hospital, Kenya: a prospective cohort study by Aiken, Alexander M, Dr, Mturi, Neema, MRCPCH, Njuguna, Patricia, MMed, Mohammed, Shebe, HND, Berkley, James A, MD, Mwangi, Isaiah, MMed, Mwarumba, Salim, MSc, Kitsao, Barnes S, HND, Lowe, Brett S, MPhil, Morpeth, Susan C, FRCPA, Hall, Andrew J, Prof, Khandawalla, Iqbal, MSurg, Scott, J Anthony G, Prof

“…Summary Background In sub-Saharan Africa, community-acquired bacteraemia is an important cause of illness and death in children. Our aim was to establish the…”
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Pneumococcal Conjugate Vaccine Given Shortly After Birth Stimulates Effective Antibody Concentrations and Primes Immunological Memory for Sustained Infant Protection by Scott, J. Anthony G., Ojal, John, Ashton, Lindsey, Muhoro, Anne, Burbidge, Polly, Goldblatt, David

“…Background. In developing countries, newborn immunization with pneumococcal conjugate vaccines (PCVs) could protect young infants who are at high risk of…”
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Observational study: 27 years of severe malaria surveillance in Kilifi, Kenya by Njuguna, Patricia, Maitland, Kathryn, Nyaguara, Amek, Mwanga, Daniel, Mogeni, Polycarp, Mturi, Neema, Mohammed, Shebe, Mwambingu, Gabriel, Ngetsa, Caroline, Awuondo, Kenedy, Lowe, Brett, Adetifa, Ifedayo, Scott, J Anthony G, Williams, Thomas N, Atkinson, Sarah, Osier, Faith, Snow, Robert W, Marsh, Kevin, Tsofa, Benjamin, Peshu, Norbert, Hamaluba, Mainga, Berkley, James A, Newton, Charles R J, Fondo, John, Omar, Anisa, Bejon, Philip

“…Many parts of Africa have witnessed reductions in Plasmodium falciparum transmission over the last 15 years. Since immunity to malaria is acquired more rapidly…”
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Bacteremia among Children Admitted to a Rural Hospital in Kenya by Berkley, James A, Lowe, Brett S, Mwangi, Isaiah, Williams, Thomas, Bauni, Evasius, Mwarumba, Saleem, Ngetsa, Caroline, Slack, Mary P.E, Njenga, Sally, Hart, C. Anthony, Maitland, Kathryn, English, Mike, Marsh, Kevin, Scott, J. Anthony G

“…At a rural district hospital in Kenya, nearly 13 percent of infants were found to have bacteremia on admission, as were nearly 6 percent of all children who…”
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Pneumonia research to reduce childhood mortality in the developing world by Scott, J Anthony G, Brooks, W Abdullah, Peiris, J S Malik, Holtzman, Douglas, Mulholland, E Kim

“…Pneumonia is an illness, usually caused by infection, in which the lungs become inflamed and congested, reducing oxygen exchange and leading to cough and…”
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