Search Results - "Scott, Gillian"
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Congenital cytomegalovirus infection in pregnancy: a review of prevalence, clinical features, diagnosis and prevention
Published in Australian & New Zealand journal of obstetrics & gynaecology (01-02-2016)“…Human cytomegalovirus (CMV) is under‐recognised, despite being the leading infectious cause of congenital malformation, affecting ~0.3% of Australian live…”
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Differential Expression of PDGF Receptor-α in Human Placental Trophoblasts Leads to Different Entry Pathways by Human Cytomegalovirus Strains
Published in Scientific reports (23-01-2020)“…Human cytomegalovirus (CMV) is the leading non-genetic cause of fetal malformation in developed countries. CMV placental infection is a pre-requisite for…”
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Prevention of congenital cytomegalovirus complications by maternal and neonatal treatments: a systematic review
Published in Reviews in medical virology (01-11-2014)“…SUMMARY Human cytomegalovirus is the leading non‐genetic cause of congenital malformation in developed countries. Congenital CMV may result in fetal and…”
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Human cytomegalovirus-induces cytokine changes in the placenta with implications for adverse pregnancy outcomes
Published in PloS one (31-12-2012)“…Human cytomegalovirus (CMV) infection of the developing fetus can result in adverse pregnancy outcomes including death in utero. Fetal injury results from…”
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Human cytomegalovirus directly modulates expression of chemokine CCL2 (MCP-1) during viral replication
Published in Journal of general virology (01-11-2013)“…Human cytomegalovirus (CMV) infects monocytes and other haematopoietic progenitor cells which then act as reservoirs for latency and virus dissemination. The…”
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Adenovirus Late-Phase Infection Is Controlled by a Novel L4 Promoter
Published in Journal of Virology (01-07-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multidrug Resistance Conferred by Novel DNA Polymerase Mutations in Human Cytomegalovirus Isolates
Published in Antimicrobial Agents and Chemotherapy (01-01-2007)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cytomegalovirus Infection During Pregnancy With Maternofetal Transmission Induces a Proinflammatory Cytokine Bias in Placenta and Amniotic Fluid
Published in The Journal of infectious diseases (15-04-2012)“…Congenital infection with cytomegalovirus (CMV) can induce immune responses and placental damage. By use of immunoassay panels, 27 cytokines were assessed in…”
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New insight into the phosphorylation-regulated intranuclear localization of human cytomegalovirus pUL69 mediated by cyclin-dependent kinases (CDKs) and viral CDK orthologue pUL97
Published in Journal of general virology (01-01-2016)“…Cyclin-dependent kinases (CDKs) are multifaceted regulators involved in the replication of human cytomegalovirus. Recently, we demonstrated an interaction of…”
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Mouse mammary tumour virus-like virus (MMTV-LV) is present within the liver in a wide range of hepatic disorders and unrelated to nuclear p53 expression or hepatocarcinogenesis
Published in Journal of hepatology (01-03-2009)“…Background/Aims The human equivalent of mouse mammary tumour virus (MMTV-LV) may have a role in the pathogenesis of primary biliary cirrhosis (PBC) and breast…”
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Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity
Published in The Journal of biological chemistry (27-03-2009)“…Replication of human cytomegalovirus (HCMV) is subject to regulation by cellular protein kinases. Recently, we and others reported that inhibition of…”
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The interplay between host and viral factors in shaping the outcome of cytomegalovirus infection
Published in Immunology and cell biology (01-01-2007)“…Cytomegalovirus (CMV) remains a major human pathogen causing significant morbidity and mortality in immunosuppressed or immunoimmature individuals. Although…”
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Prevalence of viruses in stool of premature neonates at a neonatal intensive care unit
Published in Journal of paediatrics and child health (01-03-2013)“…Aim Premature neonates represent a population highly vulnerable to infection. This study aims to profile viral colonisation of gut and the associated clinical…”
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Institutional biobanking: an integral part of contemporary pathology practice
Published in Pathology (01-01-2015)Get full text
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15
Genotypic analysis of two hypervariable human cytomegalovirus genes
Published in Journal of medical virology (01-09-2008)“…Most human cytomegalovirus (HCMV) genes are highly conserved in sequence among strains, but some exhibit a substantial degree of variation. Two of these genes…”
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Successful valganciclovir treatment of post-transplant cytomegalovirus infection in the presence of UL97 mutation N597D
Published in Journal of medical virology (01-03-2009)“…Mutations in the human cytomegalovirus (CMV) UL97 protein kinase are the most common mechanism of ganciclovir (GCV) resistance in the clinical setting. A CMV…”
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Emergence and persistence of multiple antiviral-resistant CMV strains in a highly immunocompromised child
Published in Journal of clinical virology (01-10-2007)“…Abstract Background The emergence of human cytomegalovirus (CMV) antiviral resistance plays a significant role in disease progression in immunocompromised…”
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Successful Corneal Autograft After Clearance of Anterior Chamber Cytomegalovirus With Oral Valganciclovir in a Patient With Multiple Failed Corneal Allografts
Published in Cornea (01-09-2011)“…PURPOSE:To report a case of recurrent corneal graft failure because of cytomegalovirus (CMV) infection and to demonstrate successful clearance of the virus…”
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Identification of putative functional motifs in viral proteins essential for human cytomegalovirus DNA replication
Published in Virus genes (01-10-2008)“…Six of the eleven genes essential for Human cytomegalovirus (HCMV) DNA synthesis have been analyzed for putative structural motifs that may have a significant…”
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Nuclear matrix localization and SUMO-1 modification of adenovirus type 5 E1b 55K protein are controlled by E4 Orf6 protein
Published in Journal of general virology (01-02-2003)“…Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK Correspondence Keith N. Leppard Keith.Leppard{at}warwick.ac.uk Human adenovirus…”
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