Search Results - "Scott, Gary"

Exploring the sequence space for (tri-)peptide self-assembly to design and discover new hydrogels by Frederix, Pim W. J. M., Scott, Gary G., Abul-Haija, Yousef M., Kalafatovic, Daniela, Pappas, Charalampos G., Javid, Nadeem, Hunt, Neil T., Ulijn, Rein V., Tuttle, Tell

“…Peptides that self-assemble into nanostructures are of tremendous interest for biological, medical, photonic and nanotechnological applications. The enormous…”
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The oldest hand-axes in Europe by Scott, Gary R., Gibert, Luis

“…Bridging the gap A key transition in the history of technology was that from the simple chopper-like tools used by the earliest stone-using hominins to the…”
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Cell Surface-Bound IL-1α Is an Upstream Regulator of the Senescence-Associated IL-6/IL-8 Cytokine Network by Orjalo, Arturo V., Bhaumik, Dipa, Gengler, Bridget K., Scott, Gary K., Campisi, Judith, Karin, Michael

“…Inflammation underlies most age-related diseases, including cancer, but the etiology is poorly understood. One proposed factor is the presence of senescent…”
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Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies by Mattie, Michael D, Benz, Christopher C, Bowers, Jessica, Sensinger, Kelly, Wong, Linda, Scott, Gary K, Fedele, Vita, Ginzinger, David, Getts, Robert, Haqq, Chris

“…Recent studies indicate that microRNAs (miRNAs) are mechanistically involved in the development of various human malignancies, suggesting that they represent a…”
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Tripeptide Emulsifiers by Scott, Gary G., McKnight, Paul J., Tuttle, Tell, Ulijn, Rein V.

“…A series of tripeptides is shown to form emulsions with sequence tunable properties. Using a combination of simulations and experiments, it is shown that two…”
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Polymeric peptide pigments with sequence-encoded properties by Lampel, Ayala, McPhee, Scott A., Park, Hang-Ah, Scott, Gary G., Humagain, Sunita, Hekstra, Doeke R., Yoo, Barney, Frederix, Pim W. J. M., Li, Tai-De, Abzalimov, Rinat R., Greenbaum, Steven G., Tuttle, Tell, Hu, Chunhua, Bettinger, Christopher J., Ulijn, Rein V.

“…Melanins are a family of heterogeneous polymeric pigments that provide ultraviolet (UV) light protection, structural support, coloration, and free radical…”
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Breast Cancer Metastasis Suppressor 1 Up-regulates miR-146, Which Suppresses Breast Cancer Metastasis by HURST, Douglas R, EDMONDS, Mick D, SCOTT, Gary K, BENZ, Christopher C, VAIDYA, Kedar S, WELCH, Danny R

“…Breast cancer metastasis suppressor 1 (BRMS1) is a predominantly nuclear protein that differentially regulates expression of multiple genes, leading to…”
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Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells by An, Mahru C., Zhang, Ningzhe, Scott, Gary, Montoro, Daniel, Wittkop, Tobias, Mooney, Sean, Melov, Simon, Ellerby, Lisa M.

“…Huntington's disease (HD) is caused by a CAG expansion in the huntingtin gene. Expansion of the polyglutamine tract in the huntingtin protein results in…”
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Coordinate Suppression of ERBB2 and ERBB3 by Enforced Expression of Micro-RNA miR-125a or miR-125b by Scott, Gary K., Goga, Andrei, Bhaumik, Dipa, Berger, Crystal E., Sullivan, Christopher S., Benz, Christopher C.

“…Deregulation of micro-RNAs (miRNAs) is emerging as a major aspect of cancer etiology because their capacity to direct the translation and stability of targeted…”
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Fluorescence Quenching in Conjugated Polymers Blended with Reduced Graphitic Oxide by Wang, Yaobing, Kurunthu, Dharmalingam, Scott, Gary W, Bardeen, Christopher J

“…Conjugated polymers blended with graphene represent a possible approach for making organic bulk heterojunction solar cells. In this paper, the time-resolved…”
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Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype by Wiley, Christopher D., Schaum, Nicholas, Alimirah, Fatouma, Lopez-Dominguez, Jose Alberto, Orjalo, Arturo V., Scott, Gary, Desprez, Pierre-Yves, Benz, Christopher, Davalos, Albert R., Campisi, Judith

“…Processes that have been linked to aging and cancer include an inflammatory milieu driven by senescent cells. Senescent cells lose the ability to divide,…”
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Biorefinery: Ensuring biomass as a sustainable renewable source of chemicals, materials, and energy by Liu, Shijie, Abrahamson, Lawrence P., Scott, Gary M.

“…The Second International Biorefinery Conference was held in Syracuse, New York, October 6–7, 2009. Biorefinery and its potentials are discussed in this…”
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Brain transcriptomic, metabolic and mitohormesis properties associated with N-propargylglycine treatment: A prevention strategy against neurodegeneration by Teramayi, Fadzai, Bons, Joanna, Scott, Madeleine, Scott, Gary K., Loureiro, Ashley, Lopez-Ramirez, Alejandro, Schilling, Birgit, Ellerby, Lisa M., Benz, Christopher C.

“…[Display omitted] •Treatment of HD or control mice with N-propargylglycine (N-PPG) induced mitohormesis.•Metabolomics revealed increased levels of proline,…”
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MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8 by Bhaumik, Dipa, Scott, Gary K, Schokrpur, Shiruyeh, Patil, Christopher K, Orjalo, Arturo V, Rodier, Francis, Lithgow, Gordon J, Campisi, Judith

“…Senescence is a cellular program that irreversibly arrests the proliferation of damaged cells and induces the secretion of the inflammatory mediators IL- 6 and…”
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early Australopithecus afarensis postcranium from Woranso-Mille, Ethiopia by Haile-Selassie, Yohannes, Latimer, Bruce M, Alene, Mulugeta, Deino, Alan L, Gibert, Luis, Melillo, Stephanie M, Saylor, Beverly Z, Scott, Gary R, Lovejoy, C. Owen

“…Only one partial skeleton that includes both forelimb and hindlimb elements has been reported for Australopithecus afarensis. The diminutive size of this…”
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Rapid alteration of MicroRNA levels by histone deacetylase inhibition by SCOTT, Gary K, MATTIE, Michael D, BERGER, Crystal E, BENZ, Stephen C, BENZ, Christopher C

“…Improved understanding of the molecular mechanisms by which small-molecule inhibitors of histone deacetylases (HDAC) induce programs, such as cellular…”
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New species from Ethiopia further expands Middle Pliocene hominin diversity by Haile-Selassie, Yohannes, Gibert, Luis, Melillo, Stephanie M., Ryan, Timothy M., Alene, Mulugeta, Deino, Alan, Levin, Naomi E., Scott, Gary, Saylor, Beverly Z.

“…Middle Pliocene hominin species diversity has been a subject of debate over the past two decades, particularly after the naming of Australopithecus…”
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Targeting Mitochondrial Proline Dehydrogenase with a Suicide Inhibitor to Exploit Synthetic Lethal Interactions with p53 Upregulation and Glutaminase Inhibition by Scott, Gary K, Yau, Christina, Becker, Beatrice C, Khateeb, Sana, Mahoney, Sophia, Jensen, Martin Borch, Hann, Byron, Cowen, Bryan J, Pegan, Scott D, Benz, Christopher C

“…Proline dehydrogenase (PRODH) is a p53-inducible inner mitochondrial membrane flavoprotein linked to electron transport for anaplerotic glutamate and ATP…”
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Erythropoietin: powerful protection of ischemic and post-ischemic brain by Nguyen, Anh Q, Cherry, Brandon H, Scott, Gary F, Ryou, Myoung-Gwi, Mallet, Robert T

“…Ischemic brain injury inflicted by stroke and cardiac arrest ranks among the leading causes of death and long-term disability in the United States. The brain…”
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Noncovalent Inhibition and Covalent Inactivation of Proline Dehydrogenase by Analogs of N‑Propargylglycine by Tanner, John J., Ji, Juan, Bogner, Alexandra N., Scott, Gary K., Patel, Sagar M., Seravalli, Javier, Gates, Kent S., Benz, Christopher C., Becker, Donald F.

“…The flavoenzyme proline dehydrogenase (PRODH) catalyzes the first step of proline catabolism, the oxidation of l-proline to Δ1-pyrroline-5-carboxylate. The…”
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