Search Results - "Scott, G J"
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The epidemiology and global burden of autism spectrum disorders
Published in Psychological medicine (01-02-2015)“…Autism spectrum disorders (ASDs) are persistent disabling neurodevelopmental disorders clinically evident from early childhood. For the first time, the burden…”
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2
Dopamine, psychosis and schizophrenia: the widening gap between basic and clinical neuroscience
Published in Translational psychiatry (31-01-2018)“…The stagnation in drug development for schizophrenia highlights the need for better translation between basic and clinical research. Understanding the…”
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3
A heavy burden on young minds: the global burden of mental and substance use disorders in children and youth
Published in Psychological medicine (01-05-2015)“…Mental and substance use disorders are common and often persistent, with many emerging in early life. Compared to adult mental and substance use disorders, the…”
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Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis
Published in The Lancet (British edition) (20-04-2013)“…Summary Background The annual number of hospital admissions and in-hospital deaths due to severe acute lower respiratory infections (ALRI) in young children…”
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Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study
Published in The Lancet (British edition) (08-10-2011)“…Summary Background Many investigators have suggested that malaria infection predisposes individuals to bacteraemia. We tested this hypothesis with mendelian…”
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6
Use of vaccines as probes to define disease burden
Published in The Lancet (British edition) (17-05-2014)“…Summary Vaccine probe studies have emerged in the past 15 years as a useful way to characterise disease. By contrast, traditional studies of vaccines focus on…”
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Psychotic experiences and psychological distress predict contemporaneous and future non-suicidal self-injury and suicide attempts in a sample of Australian school-based adolescents
Published in Psychological medicine (01-01-2015)“…Recent cross-sectional studies have shown psychotic experiences (PEs) are associated with suicidal ideation and behaviours. We aimed to examine associations…”
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Profile: The Kilifi Health and Demographic Surveillance System (KHDSS)
Published in International journal of epidemiology (01-06-2012)“…The Kilifi Health and Demographic Surveillance System (KHDSS), located on the Indian Ocean coast of Kenya, was established in 2000 as a record of births,…”
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9
defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus
Published in Proceedings of the National Academy of Sciences - PNAS (27-04-2010)“…Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease more prevalent in people of African and Asian origin than Caucasian origin. FcγRIIb is…”
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10
The prevalence and risk factors for pneumococcal colonization of the nasopharynx among children in Kilifi District, Kenya
Published in PloS one (20-02-2012)“…Pneumococcal conjugate vaccines (PCV) reduce nasopharyngeal carriage of vaccine-serotype pneumococci but increase in the carriage of non-vaccine serotypes. We…”
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The impact of introduction of the 10-valent pneumococcal conjugate vaccine on pneumococcal carriage in Nigeria
Published in Nature communications (09-05-2023)“…Pneumococcal conjugate vaccines (PCVs) protect against invasive pneumococcal disease (IPD) among vaccinees. However, at population level, this protection is…”
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The epidemiology of fecal carriage of nontyphoidal Salmonella among healthy children and adults in three sites in Kenya
Published in PLoS neglected tropical diseases (01-10-2023)“…Despite the importance of non-Typhoidal Salmonella (NTS) disease in Africa, epidemiologic data on carriage and transmission are few. These data are important…”
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13
Objective Bayesian model selection in Gaussian graphical models
Published in Biometrika (01-09-2009)“…This paper presents a default model-selection procedure for Gaussian graphical models that involves two new developments. First, we develop a default version…”
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The Descriptive Epidemiology of Streptococcus pneumoniae and Haemophilus influenzae Nasopharyngeal Carriage in Children and Adults in Kilifi District, Kenya
Published in The Pediatric infectious disease journal (01-01-2008)“…BACKGROUND:Transmission and nasopharyngeal colonization are necessary steps en route to invasive pneumococcal or Haemophilus influenzae disease but their…”
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Nasopharyngeal Pneumococcal Carriage in Nigeria: a two-site, population-based survey
Published in Scientific reports (22-02-2018)“…Changes in nasopharyngeal (NP) carriage of vaccine-type (VT) Streptococcus pneumoniae can be used to assess the effectiveness of a pneumococcal conjugate…”
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Pneumococcal Conjugate Vaccine Given Shortly After Birth Stimulates Effective Antibody Concentrations and Primes Immunological Memory for Sustained Infant Protection
Published in Clinical infectious diseases (01-10-2011)“…Background. In developing countries, newborn immunization with pneumococcal conjugate vaccines (PCVs) could protect young infants who are at high risk of…”
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Overcoming super‐knock down resistance (super‐kdr) mediated resistance: multi‐halogenated benzyl pyrethroids are more toxic to super‐kdr than kdr house flies
Published in Insect molecular biology (01-04-2016)“…Target site insensitivity because of mutations in the voltage‐sensitive sodium channel gene (Vssc) is a major mechanism of resistance to pyrethroid…”
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Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game
Published in British journal of cancer (03-01-2012)“…Background: Tumours are made up of a mixed population of different types of cells that include normal structures as well as ones associated with the…”
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The indirect health effects of malaria estimated from health advantages of the sickle cell trait
Published in Nature communications (20-02-2019)“…Most estimates of the burden of malaria are based on its direct impacts; however, its true burden is likely to be greater because of its wider effects on…”
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Invasive Group A Streptococcus Infection among Children, Rural Kenya
Published in Emerging infectious diseases (01-02-2016)“…To determine the extent of group A Streptococcus (GAS) infections in sub-Saharan Africa and the serotypes that cause disease, we analyzed surveillance data for…”
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