Search Results - "Scott, Fraser J."

Selective Anti-Leishmanial Strathclyde Minor Groove Binders Using an N-Oxide Tail-Group Modification by Perieteanu, Marina C, McGee, Leah M C, Shaw, Craig D, MacMillan, Donna S, Khalaf, Abedawn I, Gillingwater, Kirsten, Beveridge, Rebecca, Carter, Katharine C, Suckling, Colin J, Scott, Fraser J

“…The neglected tropical disease leishmaniasis, caused by Leishmania spp., is becoming more problematic due to the emergence of drug-resistant strains…”
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Surface Immobilization of Bio-Functionalized Cubosomes: Sensing of Proteins by Quartz Crystal Microbalance by Fraser, Scott J, Mulet, Xavier, Martin, Lisandra, Praporski, Slavica, Mechler, Adam, Hartley, Patrick G, Polyzos, Anastasios, Separovic, Frances

“…A strategy for tethering lipid liquid crystalline submicrometer particles (cubosomes) to a gold surface for the detection of proteins is reported…”
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Cyrene™ is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens by Camp, Jason E, Nyamini, Simbarashe B, Scott, Fraser J

“…Dimethyl sulfoxide (DMSO) is currently employed across the biomedical field, from cryopreservation to in vitro assays, despite the fact that it has been shown…”
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Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders by Kennedy, Alan R, Khalaf, Abedawn I, Scott, Fraser J, Suckling, Colin J

“…The title nitro-pyrrole-based compounds, C H N O , (I) (ethyl 4-nitro-1 -pyrrole-2-carboxyl-ate), its derivative C H N O , (II) [ethyl…”
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Students' reflections on an employability skills provision by Scott, Fraser J., Willison, Debra

“…For many years, a key driver for Higher Education Institutions (HEIs) has been ensuring that students are prepared for employment post-graduation. This has…”
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Empowering students by enhancing their employability skills by Scott, Fraser J., Connell, Pauline, Thomson, Linda A., Willison, Debra

“…Recognising the importance of graduates being equipped with appropriate employability skills alongside their subject-specific skills, we have had transferable…”
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Introducing Graduate Employability Skills to Year 1 Chemistry Students: Reflecting Upon Impact by Gibson van Mil, Lorraine, De Pascale, Egizia, Thomson, Patrick I. T., Walker, Sarah, Scott, Fraser J.

“…Employability skills training is an important aspect of undergraduate chemistry degrees to ensure good graduate outcomes for students. In response to changes…”
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How Safe Is Your Playground? Analyzing Soil in Scottish Schools through a University Outreach Project by Willison, Debra, Davidson, Christine M, Scott, Fraser J

“…School pupils often perceive STEM subjects to be challenging; thus, in this project, an interactive, nationwide STEM investigation was designed to stimulate…”
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ChemDiverse: A Chemistry Careers Activity Showcasing Diversity by Velasquez, Sara T. R., Nimmo, Roslyn, Pookayil, Teena, Lydon, Christopher, Willison, Debra, Scott, Fraser J.

“…Women, ethnic minority, and less affluent groups are widely underrepresented in chemistry, a problem that is observed at all levels but begins before college…”
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Strathclyde minor groove binders (S-MGBs) with activity against Acanthamoeba castellanii by Mcgee, Leah M C, Carpinteyro Sanchez, Alemao G, Perieteanu, Marina, Eskandari, Kaveh, Bian, Yan, Mackie, Logan, Young, Louise, Beveridge, Rebecca, Suckling, Colin J, Roberts, Craig W, Scott, Fraser J

“…Abstract Background Acanthamoeba spp. is the causative agent of Acanthamoeba keratitis and granulomatous amoebic encephalitis. Strathclyde minor groove binders…”
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Controlling nanostructure and lattice parameter of the inverse bicontinuous cubic phases in functionalised phytantriol dispersions by Fraser, Scott J., Mulet, Xavier, Hawley, Adrian, Separovic, Frances, Polyzos, Anastasios

“…[Display omitted] •Functionalisation of inverse bicontinuous cubic phase lyotropic liquid crystalline dispersions is demonstrated.•Oleic acid and…”
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Crystal structure of N,N-dimethyl-2-[(4-methyl-benz-yl)sulfon-yl]ethanamine by Kennedy, Alan R, Khalaf, Abedawn I, Scott, Fraser J, Suckling, Colin J

“…In the crystal, the title compound, C12H19NO2S, has a disordered structure with two equally populated conformations of the amine fragment. A pair of weak C-H⋯O…”
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Preparation of a Polymeric Foam: An Activity Designed to Increase Teachers’ Awareness of the Utility of Condensation Polymerization by Cullen, John, Scott, Fraser J

“…The new Scottish “Curriculum for Excellence” places a greater emphasis on the societal implications of chemistry concepts, including polymer chemistry. This…”
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Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced Arthritis by Al-Riyami, Lamyaa, Pineda, Miguel A, Rzepecka, Justyna, Huggan, Judith K, Khalaf, Abedawn I, Suckling, Colin J, Scott, Fraser J, Rodgers, David T, Harnett, Margaret M, Harnett, William

“…In spite of increasing evidence that parasitic worms may protect humans from developing allergic and autoimmune diseases and the continuing identification of…”
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Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model by Giordani, Federica, Khalaf, Abedawn I, Gillingwater, Kirsten, Munday, Jane C, de Koning, Harry P, Suckling, Colin J, Barrett, Michael P, Scott, Fraser J

“…Animal African trypanosomiasis (AAT) is a significant socioeconomic burden for sub-Saharan Africa because of its huge impact on livestock health. Existing…”
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Decision-making factors of female A-level chemistry students when choosing to study a degree in chemistry by Crossdale, Rachel, Scott, Fraser J., Sweeney, Gemma

“…Gender issues, and specifically the lack of women in the physical sciences, has been a subject of intense debate for decades. The problem is so acute, that…”
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A Simulated peer-assessment approach to improve students' performance in numerical problem-solving questions in high school biology by Scott, Fraser J.

“…Basic mathematical fluency is a prerequisite for success in a wide array of areas in biology and it has been noted that many students are deficient in this…”
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Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to Mycobacterium tuberculosis infection by Kieswetter, Nathan S., Ozturk, Mumin, Hlaka, Lerato, Chia, Julius Ebua, Nichol, Ryan J. O., Cross, Jasmine M., McGee, Leah M. C., Tyson-Hirst, Izaak, Beveridge, Rebecca, Brombacher, Frank, Carter, Katharine C., Suckling, Colin J., Scott, Fraser J., Guler, Reto

“…Abstract Background Previously, we evaluated the intracellular mycobactericidal activity of the minor groove binder, S-MGB-364 against the clinical…”
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Correction to “Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model” by Giordani, Federica, Khalaf, Abedawn I, Gillingwater, Kirsten, Munday, Jane C, de Koning, Harry P, Suckling, Colin J, Barrett, Michael P, Scott, Fraser J

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Is Mathematics to Blame? An Investigation into High School Students' Difficulty in Performing Calculations in Chemistry by Scott, Fraser J

“…Mathematical ability is a major contributory factor to the success of a student in any science course. This paper aims to determine the source of the…”
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