Search Results - "Scott, D. W"

BCL2 mutations in diffuse large B-cell lymphoma by Schuetz, J M, Johnson, N A, Morin, R D, Scott, D W, Tan, K, Ben-Nierah, S, Boyle, M, Slack, G W, Marra, M A, Connors, J M, Brooks-Wilson, A R, Gascoyne, R D

“…BCL2 is deregulated in diffuse large B-cell lymphoma (DLBCL) by the t(14;18) translocation, gene amplification and/or nuclear factor-κB signaling. RNA-seq data…”
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IL10 receptor is a novel therapeutic target in DLBCLs by Béguelin, W, Sawh, S, Chambwe, N, Chan, F C, Jiang, Y, Choo, J-W, Scott, D W, Chalmers, A, Geng, H, Tsikitas, L, Tam, W, Bhagat, G, Gascoyne, R D, Shaknovich, R

“…Diffuse large B-cell lymphoma (DLBCL) is a biologically and clinically heterogeneous disease with marked genomic instability and variable response to…”
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10th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals by Tourdot, S., Abdolzade-Bavil, A., Bessa, J., Broët, P., Fogdell-Hahn, A., Giorgi, M., Jawa, V., Kuranda, K., Legrand, N., Pattijn, S., Pedras-Vasconcelos, J. A., Rudy, A., Salmikangas, P., Scott, D. W., Snoeck, V., Smith, N., Spindeldreher, S., Kramer, D.

“…Therapeutic proteins and emerging gene and cell-based therapies are attractive therapeutic tools for addressing unmet medical needs or when earlier…”
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Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation by Shanks, K., Nkyimbeng-Takwi, E.H., Smith, E., Lipsky, M.M., DeTolla, L.J., Scott, D.W., Keegan, A.D., Chapoval, S.P.

“…•We examined the changes in lung responses to allergen in Sema4D−/− and WT mice.•Allergic lung response was downregulated in Sema4D−/− mice as compared to WT…”
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Endogenous Expansion of Regulatory T Cells Leads to Long‐Term Islet Graft Survival in Diabetic NOD Mice by Shi, Q., Lees, J. R., Scott, D. W., Farber, D. L., Bartlett, S. T.

“…Donor pancreatic lymph node cells (PLNC) protect islet transplants in Non‐obese diabetic (NOD) mice. We hypothesized that induced FoxP3+ regulatory T cells…”
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Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4 regulatory T cells and TGF-β? by SONG, L, WANG, J, SOUKHAREVA, N, SHEN, B, WANG, R, YU, M, SUN, Y, HAN, G, LI, Y, QIAN, J, SCOTT, D. W, KANG, Y

“…Previous studies have demonstrated that antigen-specific tolerance could be induced by lipopolysaccharide (LPS)-stimulated B cells retrovirally transduced with…”
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Neuromuscular fatigability at high altitude: Lowlanders with acute and chronic exposure, and native highlanders by Ruggiero, Luca, Harrison, Scott W. D., Rice, Charles L., McNeil, Chris J.

“…Ascent to high altitude is accompanied by a reduction in partial pressure of inspired oxygen, which leads to interconnected adjustments within the…”
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Inhibitors - cellular aspects and novel approaches for tolerance by Scott, D. W.

“…Summary The immune response against therapeutic clotting factors VIII and IX (FVIII and FIX) is a major adverse event that can effectively thwart their…”
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Endothelial heterogeneity and adhesion molecules N-glycosylation: implications in leukocyte trafficking in inflammation by Scott, David W, Patel, Rakesh P

“…Inflammation is a major contributing element to a host of diseases with the interaction between leukocytes and the endothelium being key in this process. Much…”
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Observation as the initial management strategy in patients with mantle cell lymphoma by Abrisqueta, P., Scott, D.W., Slack, G.W., Steidl, C., Mottok, A., Gascoyne, R.D., Connors, J.M., Sehn, L.H., Savage, K.J., Gerrie, A.S., Villa, D.

“…Patients with mantle cell lymphoma (MCL) follow a heterogeneous clinical course. While they generally require treatment initiation shortly after diagnosis, it…”
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Long‐term follow‐up of bulky classic Hodgkin lymphoma managed with ABVD and PET‐guided RT demonstrates excellent outcomes in PET‐negative cases by Kim, J. L., Villa, D., Tonseth, R. P., Gerrie, A. S., Wilson, D., Benard, F., Venner, C. P., Skinnider, B., Farinha, P., Slack, G. W., Lo, A. C., Scott, D. W., Sehn, L. H., Savage, K. J.

“…Summary The outcome of 221 patients with bulky (≥10 cm) classic Hodgkin lymphoma (cHL) treated with doxorubicin, bleomycin, vinblastine, dacarbazine and…”
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Death the Fas way: regulation and pathophysiology of CD95 and its ligand by Sharma, K, Wang, R.X, Zhang, L.Y, Yin, D.L, Luo, X.Y, Solomon, J.C, Jiang, R.F, Markos, K, Davidson, W, Scott, D.W, Shi, Y.F

“…Apoptotic cell death mediated by the members of the tumor necrosis factor receptor family is an essential process involved in the regulation of cellular…”
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Electro-thermal control of aluminum-doped zinc oxide/vanadium dioxide multilayered thin films for smart-device applications by Skuza, J. R., Scott, D. W., Mundle, R. M., Pradhan, A. K.

“…We demonstrate the electro-thermal control of aluminum-doped zinc oxide (Al:ZnO) /vanadium dioxide (VO 2 ) multilayered thin films, where the application of a…”
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Feline Papillomas and Papillomaviruses by Sundberg, J. P., Van Ranst, M., Montali, R., Homer, B. L., Miller, W. H., Rowland, P. H., Scott, D. W., England, J. J., Dunstan, R. W., Mikaelian, I., Jenson, A. B.

“…Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are…”
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Analyses of reaction rate data for the simple hydrolysis of acetic anhydride in the acetonitrile/water and acetone/water cosolvent systems using recently developed thermodynamic rate equations by Wiseman, F. L., Scott, D. W., Tamine, J., O'Connell, R., Smarra, A., Olowoyo, S.

“…This article presents reaction rate data for the simple hydrolysis of acetic anhydride in the acetonitrile/water and acetone/water cosolvent systems and…”
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Gene therapy for immunological tolerance: using 'transgenic' B cells to treat inhibitor formation by SCOTT, D. W.

“…B cells have been shown to function as tolerogenic antigen presenting cells (APCs) both in vivo and in vitro. We have taken advantage of this property, as well…”
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Prevalence, number and morphological types of multinucleated histiocytic giant cells in equine inflammatory dermatoses: A retrospective light microscopic study of skin-biopsy specimens from 362 horses by Cohen, R.D, Scott, D.W, Erb, H.N

“…Summary Reasons for performing study: Multinucleated histiocytic giant cells (MHGC) are seen frequently in skin‐biopsy specimens from horses with inflammatory…”
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HIGHLY MULTIPLEX TISSUE IMAGING OF DLBCL IDENTIFIES NOVEL PATHOLOGICAL FEATURES PREDICTIVE OF OVERALL SURVIVAL by McNally, D. R, Ravichandran, H, Tam, W, Steidl, C, Scott, D. W, Melnick, A, Elemento, O

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Can we prevent immunogenicity of human protein drugs? by Scott, D W, De Groot, A S

“…Monoclonal antibodies have proved to be extremely valuable additions to conventional treatment for rheumatic diseases. However, despite the general trend…”
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A sub‐population of cells expressing MYC and BCL2 without BCL6 refines the definition of double expressor lymphoma (DEL) by Hoppe, M. M., Sridhar, S., Liu, M., Jaynes, P., Peng, Y., Harris, C., Bottos, A., Farinha, P., Mottok, A., Scott, D. W., Chee, Y. L., Ng, S., Tripodo, C., Jeyasekharan, A. D.

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