Search Results - "Scott, Cheryl Siegel"

Trichloroethylene and cancer: systematic and quantitative review of epidemiologic evidence for identifying hazards by Scott, Cheryl Siegel, Jinot, Jennifer

“…We conducted a meta-analysis focusing on studies with high potential for trichloroethylene (TCE) exposure to provide quantitative evaluations of the evidence…”
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Human health effects of trichloroethylene: key findings and scientific issues by Chiu, Weihsueh A, Jinot, Jennifer, Scott, Cheryl Siegel, Makris, Susan L, Cooper, Glinda S, Dzubow, Rebecca C, Bale, Ambuja S, Evans, Marina V, Guyton, Kathryn Z, Keshava, Nagalakshmi, Lipscomb, John C, Barone, Jr, Stanley, Fox, John F, Gwinn, Maureen R, Schaum, John, Caldwell, Jane C

“…In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) completed a toxicological review of…”
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Human health effects of tetrachloroethylene: key findings and scientific issues by Guyton, Kathryn Z, Hogan, Karen A, Scott, Cheryl Siegel, Cooper, Glinda S, Bale, Ambuja S, Kopylev, Leonid, Barone, Stanley, Makris, Susan L, Glenn, Barbara, Subramaniam, Ravi P, Gwinn, Maureen R, Dzubow, Rebecca C, Chiu, Weihsueh A

“…The U.S. Environmental Protection Agency (EPA) completed a toxicological review of tetrachloroethylene (perchloroethylene, PCE) in February 2012 in support of…”
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A review of potential neurotoxic mechanisms among three chlorinated organic solvents by Bale, Ambuja S., Barone, Stan, Scott, Cheryl Siegel, Cooper, Glinda S.

“…The potential for central nervous system depressant effects from three widely used chlorinated solvents, trichloroethylene (TCE), perchloroethylene (PERC), and…”
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Trichloroethylene Cancer Epidemiology: A Consideration of Select Issues by Scott, Cheryl Siegel, Chiu, Weihsueh A.

“…A large body of epidemiologic evidence exists for exploring causal associations between cancer and trichloroethylene (TCE) exposure. The U.S. Environmental…”
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Key Scientific Issues in the Health Risk Assessment of Trichloroethylene by Chiu, Weihsueh A., Caldwell, Jane C., Keshava, Nagalakshmi, Scott, Cheryl Siegel

“…Trichloroethylene (TCE) is a common environmental contaminant at hazardous waste sites and in ambient and indoor air. Assessing the human health risks of TCE…”
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Early lifestage exposure and potential developmental susceptibility to tetrachloroethylene by Brown Dzubow, Rebecca, Makris, Susan, Siegel Scott, Cheryl, Barone Jr, Stanley

“…BACKGROUND: Tetrachloroethylene, also known as perchloroethylene or “perc”, is a highly volatile and lipophilic solvent widely used in dry cleaning, textile…”
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Comments on Article "Applying Mode-of-Action and Pharmacokinetic Considerations in Contemporary Cancer Risk Assessments: An Example with Trichloroethylene" by Clewell and Andersen/Response to Comments by Caldwell et al. on Article "Applying Mode-of-Action and Pharmacokinetic Considerations in Contemporary Cancer Risk Assessments: An Example with Trichloroethylene" by Caldwell, Jane C, Evans, Marina V, Marcus, Allan H, Scott, Cheryl Siegel

“…In their 2004 article, Clewell and Andersen provide their perspective on the application of mode-of-action (MOA) and pharmacokinetic considerations in…”
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Carcinogenicity of Trichloroethylene by Wartenberg, Daniel, Scott, Cheryl Siegel

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A Reexamination of the PPAR-α Activation Mode of Action as a Basis for Assessing Human Cancer Risks of Environmental Contaminants by Guyton, Kathryn Z., Chiu, Weihsueh A., Bateson, Thomas F., Jinot, Jennifer, Scott, Cheryl Siegel, Brown, Rebecca C., Caldwell, Jane C.

“…Background: Diverseenvironmcntal contaminants, including the plasticizerdi(2-ethylhexyl)phthalate (DEHP), are hepatocarcinogenic peroxisome proliferators in…”
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A systematic evaluation of the potential effects of trichloroethylene exposure on cardiac development by Makris, Susan L., Scott, Cheryl Siegel, Fox, John, Knudsen, Thomas B., Hotchkiss, Andrew K., Arzuaga, Xabier, Euling, Susan Y., Powers, Christina M., Jinot, Jennifer, Hogan, Karen A., Abbott, Barbara D., Hunter, E. Sidney, Narotsky, Michael G.

“…•The evaluation of developmental cardiac defects was updated for trichloroethylene.•Evidence integration suggests prenatal TCE exposures can cause human…”
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Approaches to advancing quantitative human health risk assessment of environmental chemicals in the post-genomic era by Chiu, Weihsueh A., Euling, Susan Y., Scott, Cheryl Siegel, Subramaniam, Ravi P.

“…The contribution of genomics and associated technologies to human health risk assessment for environmental chemicals has focused largely on elucidating…”
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Insights from epidemiology into dichloromethane and cancer risk by Cooper, Glinda S, Scott, Cheryl Siegel, Bale, Ambuja S

“…Dichloromethane (methylene chloride) is a widely used chlorinated solvent. We review the available epidemiology studies (five cohort studies, 13 case-control…”
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A systematic review and meta-analysis of occupational exposure to trichloroethylene and cancers of the kidney and liver and non-Hodgkin lymphoma by Scott, Cheryl Siegel, Jinot, Jennifer

“…Objectives Two advisory panels reviewing the epidemiologic evidence on cancer and trichlorethylene (TCE) recommended meta-analysis as an approach to synthesise…”
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Approaches to advancing quantitative human health risk assessment of environmental chemicals in the post-genomic era: Toxicogenomics in Risk Assessment by CHIU, Weihsueh A, EULING, Susan Y, SCOTT, Cheryl Siegel, SUBRAMANIAM, Ravi P

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Trichloroethylene and Cancer: Epidemiologic Evidence by Wartenberg, Daniel, Reyner, Daniel, Scott, Cheryl Siegel

“…Trichloroethylene is an organic chemical that has been used in dry cleaning, for metal degreasing, and as a solvent for oils and resins. It has been shown to…”
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Use of Epidemiology in Risk Assessment: Challenges and Opportunities by Christensen, Krista, Christensen, Carol H, Wright, J. Michael, Galizia, Audrey, Glenn, Barbara S, Scott, Cheryl Siegel, Mall, Jennifer K, Bateson, Thomas F, Murphy, Patricia A, Cooper, Glinda S

“…The assessment of risk from environmental and occupational exposures incorporates and synthesizes data from a variety of scientific disciplines including…”
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Quantitative estimation of the genetic risk associated with the induction of heritable translocations at low-dose exposure: ethylene oxide as an example by Rhomberg, L, Dellarco, V L, Siegel-Scott, C, Dearfield, K L, Jacobson-Kram, D

“…This paper explores how quantitative risk assessment methods might be extended to analysis of risks to the human germ line. High inhalation exposures to…”
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A Reexamination of the PPAR-[alpha] Activation Mode of Action as a Basis for Assessing Human Cancer Risks of Environmental Contaminants by Guyton, Kathryn Z, Chiu, Weihsueh A, Bateson, Thomas F, Jinot, Jennifer, Scott, Cheryl Siegel, Brown, Rebecca C, Caldwell, Jane C

“…Diverse environmental contaminants, including the plasticizer di(2-ethylhexyl)phthalate (DEHP), are hepatocarcinogenic peroxisome proliferators in rodents…”
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A Reexamination of the PPAR-a Activation Mode of Action as a Basis for Assessing Human Cancer Risks of Environmental Contaminants by Guyton, Kathryn Z, Chiu, Weihsueh A, Bateson, Thomas F, Jinot, Jennifer, Scott, Cheryl Siegel, Brown, Rebecca C, Caldwell, Jane C

“…Diverse environmental contaminants, including the plasticizer di(2-ethylhexyl)phthalate (DEHP), are hepatocarcinogenic peroxisome proliferators in rodents…”
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