Search Results - "Scott, Charles A.B."

Impact of Acarbose on Incident Diabetes and Regression to Normoglycemia in People With Coronary Heart Disease and Impaired Glucose Tolerance: Insights From the ACE Trial by Gerstein, Hertzel C, Coleman, Ruth L, Scott, Charles A B, Xu, Shishi, Tuomilehto, Jaakko, Rydén, Lars, Holman, Rury R

“…We examined the impact of acarbose, an α-glucosidase inhibitor, on incident diabetes and regression to normoglycemia in 6,522 Acarbose Cardiovascular…”
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11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial by Othonos, Nantia, Pofi, Riccardo, Arvaniti, Anastasia, White, Sarah, Bonaventura, Ilaria, Nikolaou, Nikolaos, Moolla, Ahmad, Marjot, Thomas, Stimson, Roland H., van Beek, André P., van Faassen, Martijn, Isidori, Andrea M., Bateman, Elizabeth, Sadler, Ross, Karpe, Fredrik, Stewart, Paul M., Webster, Craig, Duffy, Joanne, Eastell, Richard, Gossiel, Fatma, Cornfield, Thomas, Hodson, Leanne, Jane Escott, K., Whittaker, Andrew, Kirik, Ufuk, Coleman, Ruth L., Scott, Charles A. B., Milton, Joanne E., Agbaje, Olorunsola, Holman, Rury R., Tomlinson, Jeremy W.

“…Glucocorticoids prescribed to limit inflammation, have significant adverse effects. As 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) regenerates active…”
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1479-P: Predictors of Incident Hospitalization for Heart Failure in the ACE Trial Population by SCOTT, CHARLES A.B., MCMURRAY, JOHN J., RYDÉN, LARS, SUN, YIHONG, TENDERA, MICHAL, COLEMAN, RUTH L., HOLMAN, RURY R.

“…Background and Aims: Heart failure (HF) is a deadly complication of type 2 diabetes but little is known about its incidence in patients with coronary heart…”
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Meta-analysis of the impact of alpha-glucosidase inhibitors on incident diabetes and cardiovascular outcomes by Coleman, Ruth L, Scott, Charles A B, Lang, Zhihui, Bethel, M Angelyn, Tuomilehto, Jaakko, Holman, Rury R

“…Alpha-glucosidase inhibitors (AGIs) have been shown to reduce incident type 2 diabetes but their impact on cardiovascular (CV) disease remains controversial…”
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Predicting the risk of developing type 2 diabetes in Chinese people who have coronary heart disease and impaired glucose tolerance by Xu, Shishi, Scott, Charles A.B., Coleman, Ruth L., Tuomilehto, Jaakko, Holman, Rury R.

“…Aims Robust diabetes risk estimates in Asian patients with impaired glucose tolerance (IGT) and coronary heart disease (CHD) are lacking. We developed a…”
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Predicting heart failure events in patients with coronary heart disease and impaired glucose tolerance: Insights from the Acarbose Cardiovascular Evaluation (ACE) trial by Wamil, Malgorzata, McMurray, John J.V., Scott, Charles A.B., Coleman, Ruth L., Sun, Yihong, Standl, Eberhard, Rydén, Lars, Holman, Rury R.

“…•Higher age and plasma creatinine, lower haemoglobin, and HF, MI or AF predicted hHF.•Higher age and creatinine values predicted case fatality.•Acarbose did…”
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