Search Results - "Scotchford, Colin"

Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold by Pitrolino, Katherine A., Felfel, Reda M., Pellizzeri, Laura Macri, McLaren, Jane, Popov, Alexander A., Sottile, Virginie, Scotchford, Colin A., Scammell, Brigitte E., Roberts, George A.F., Grant, David M.

“…An innovative approach was developed to engineer a multi-layered chitosan scaffold for osteochondral defect repair. A combination of freeze drying and…”
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Impact of Serum Source on Human Mesenchymal Stem Cell Osteogenic Differentiation in Culture by Popov, Alexander, Scotchford, Colin, Grant, David, Sottile, Virginie

“…Human mesenchymal stem cells (MSCs) show promise for musculoskeletal repair applications. Animal-derived serum is extensively used for MSC culture as a source…”
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Integrated Multi-Assay Culture Model for Stem Cell Chondrogenic Differentiation by Prosser, Amy, Scotchford, Colin, Roberts, George, Grant, David, Sottile, Virginie

“…Recent osteochondral repair strategies highlight the promise of mesenchymal progenitors, an accessible stem cell source with osteogenic and chondrogenic…”
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Evaluating the cytotoxicity of Ge-Sb-Se chalcogenide glass optical fibres on 3T3 mouse fibroblasts by Mabwa, David, Kubiena, Teo, Parnell, Harriet, Su, Rong, Furniss, David, Tang, Zhuoqi, Leach, Richard, Benson, Trevor M, Scotchford, Colin A, Seddon, Angela B

“…In vivo cancer detection based on the mid-infrared molecular fingerprint of tissue is promising for the fast diagnosis and treatment of suspected cancer…”
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Physico-chemical and mechanical properties of nanocomposites prepared using cellulose nanowhiskers and poly(lactic acid) by Hossain, Kazi M. Zakir, Ahmed, Ifty, Parsons, Andrew J., Scotchford, Colin A., Walker, Gavin S., Thielemans, Wim, Rudd, Chris D.

“…A range of nanocomposites were prepared using cellulose nanowhiskers (CNWs) and poly(lactic acid) (PLA) via a solvent casting process. Acid hydrolysis process…”
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Single Solvent‐Based Film Casting Method for the Production of Porous Polymer Films by Hossain, Kazi M. Zakir, Felfel, Reda M., Ogbilikana, Prince S., Thakker, Dhruma, Grant, David M., Scotchford, Colin A., Ahmed, Ifty

“…A single solvent‐based film casting process for fabricating porous polymer films is developed in this study. The porous film is produced by mixing concentrated…”
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Functional performance of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold: a pre-clinical in vitro tribological study by Cowie, Raelene M, Macri-Pellizzeri, Laura, McLaren, Jane, Sanderson, William J, Felfel, Reda M, Scotchford, Colin A, Scammell, Brigitte E, Grant, David M, Sottile, Virginie, Jennings, Louise M

“…Osteochondral grafts are used for repair of focal osteochondral lesions. Autologous grafts are the gold standard treatment; however, limited graft availability…”
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The effect of different surface morphology and roughness on osteoblast-like cells by Ball, Michael, Grant, David M., Lo, Wei-Jen, Scotchford, Colin A.

“…Increased magnitude of biomaterial surface roughness and micromachined‐grooved surfaces has both been shown to stimulate osteoblast activity, but have not been…”
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Effect of Boron Addition on the Thermal, Degradation, and Cytocompatibility Properties of Phosphate-Based Glasses by Rudd, Chris D., Scotchford, Colin A., Furniss, David, Parsons, Andrew J., Hasan, Muhammad S., Sharmin, Nusrat, Ahmed, Ifty

“…In this study eight different phosphate-based glass compositions were prepared by melt-quenching: four in the (P2O5)45-(CaO)16-Na2O15-x-(MgO)24-B2O3x system…”
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Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation by Milborne, Ben, Murrell, Lauren, Cardillo-Zallo, Ian, Titman, Jeremy, Briggs, Louise, Scotchford, Colin, Thompson, Alexander, Layfield, Robert, Ahmed, Ifty

“…Phosphate-based glasses (PBGs) are promising materials for bone repair and regeneration as they can be formulated to be compositionally similar to the…”
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In vitro cellular testing of strontium/calcium substituted phosphate glass discs and microspheres shows potential for bone regeneration by Patel, Uresha, Macri‐Pellizzeri, Laura, Zakir Hossain, Kazi M., Scammell, Brigitte E., Grant, David M., Scotchford, Colin A., Hannon, Alex C., Kennedy, Andrew R., Barney, Emma R., Ahmed, Ifty, Sottile, Virginie

“…Phosphate‐based glasses (PBGs) are ideal materials for regenerative medicine strategies because their composition, degradation rates, and ion release profiles…”
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Development of an elastic cell culture substrate for a novel uniaxial tensile strain bioreactor by Moles, Matthew D., Scotchford, Colin A., Ritchie, Alastair Campbell

“…Bioreactors can be used for mechanical conditioning and to investigate the mechanobiology of cells in vitro. In this study a polyurethane (PU), Chronoflex AL,…”
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Cytocompatibility and Effect of Increasing MgO Content in a Range of Quaternary Invert Phosphate-based Glasses by Ahmed, Ifty, Parsons, Andrew, Jones, Arthur, Walker, Gavin, Scotchford, Colin, Rudd, Chris

“…Recently, phosphate-based glass (PBG) fibers have been used to reinforce the biodegradable polymers polycaprolactone and polylactic acid, in order to fabricate…”
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Performance of multiphase scaffolds for bone repair based on two-photon polymerized poly(d,l-lactide-co-ɛ-caprolactone), recombinamers hydrogel and nano-HA by Felfel, Reda M., Gupta, Dhanak, Zabidi, Adi Z., Prosser, Amy, Scotchford, Colin A., Sottile, Virginie, Grant, David M.

“…Multiphase hybrids were fabricated from poly(d,l-lactide-co-ɛ-caprolactone) (PLCL) copolymer scaffolds impregnated with silk-elastin-like recombinamers (SELRs)…”
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In vitro assessment of cell penetration into porous hydroxyapatite scaffolds with a central aligned channel by Rose, Felicity R., Cyster, Lesley A., Grant, David M., Scotchford, Colin A., Howdle, Steven M., Shakesheff, Kevin M.

“…There is a clinical need for synthetic scaffolds that promote bone regeneration. A common problem encountered when using scaffolds in tissue engineering is the…”
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Topographical and chemical effects of electrochemically assisted deposited hydroxyapatite coatings on osteoblast-like cells by Pegg, Elise C, Matboli, Faisal, Marriott, Tim, Khan, Imran, Scotchford, Colin A

“…A recently commercialised hydroxyapatite electrochemically assisted chemical deposition technique (BoneMaster) has been shown to induce increased bone…”
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Investigating the use of coupling agents to improve the interfacial properties between a resorbable phosphate glass and polylactic acid matrix by Hasan, Muhammad Sami, Ahmed, Ifty, Parsons, Andrew J, Rudd, Chris D, Walker, Gavin S, Scotchford, Colin A

“…Eight different chemicals were investigated as potential candidate coupling agents for phosphate glass fibre reinforced polylactic acid composites. Evidence of…”
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Influence of screw holes and gamma sterilization on properties of phosphate glass fiber-reinforced composite bone plates by Han, Na, Ahmed, Ifty, Parsons, Andrew J, Harper, Lee, Scotchford, Colin A, Scammell, Brigitte E, Rudd, Chris D

“…Polymers prepared from polylactic acid (PLA) have found a multitude of uses as medical devices. For a material that degrades, the main advantage is that an…”
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Cytocompatibility and Mechanical Properties of Short Phosphate Glass Fibre Reinforced Polylactic Acid (PLA) Composites: Effect of Coupling Agent Mediated Interface by Hasan, Muhammad Sami, Ahmed, Ifty, Parsons, Andrew, Walker, Gavin, Scotchford, Colin

“…In this study three chemical agents Amino-propyl-triethoxy-silane (APS), sorbitol ended PLA oligomer (SPLA) and Hexamethylene diisocyanate (HDI) were…”
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Mono-functional aminosilanes as primers for peptide functionalization by Pegg, Elise C., Walker, Gavin S., Scotchford, Colin A., Farrar, David, Grant, David

“…When covalently attaching biomolecules to surfaces such as titanium, trifunctional silanes are commonly used as primers to produce surface amine groups…”
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