Search Results - "Scoma, Ernest R"

Human Prune Regulates the Metabolism of Mammalian Inorganic Polyphosphate and Bioenergetics by Scoma, Ernest R., Da Costa, Renata T., Leung, Ho Hang, Urquiza, Pedro, Guitart-Mampel, Mariona, Hambardikar, Vedangi, Riggs, Lindsey M., Wong, Ching-On, Solesio, Maria E.

“…Inorganic polyphosphate (polyP) is an evolutionarily conserved and ubiquitous polymer that is present in all studied organisms. PolyP consists of…”
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Type 2 diabetes mellitus and neurodegenerative disorders: The mitochondrial connection by Baduini, Isabella R., Castro Vildosola, Jose E., Kavehmoghaddam, Sheida, Kiliç, Fatmanur, Nadeem, S. Aiman, Nizama, Juan J., Rowand, Marietta A., Annapureddy, Dileep, Bryan, Chris-Ann, Do, Lisa H., Hsiao, Samuel, Jonnalagadda, Sai A., Kasturi, Akhila, Mandava, Nikhila, Muppavaram, Sachin, Ramirez, Bryan, Siner, Aleece, Suoto, Christina N., Tamajal, Nasira, Scoma, Ernest R., Da Costa, Renata T., Solesio, Maria E.

“…The incidence of type 2 diabetes mellitus (T2DM) has increased in our society in recent decades as the population ages, and this trend is not expected to…”
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The Glacier Ice Worm, Mesenchytraeus solifugus , Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress by Osorio, Teresa, Scoma, Ernest R, Shain, Daniel H, Melissaratos, Diana S, Riggs, Lindsey M, Hambardikar, Vedangi, Solesio, Maria E

“…The inorganic polymer, polyphosphate (polyP), is present in all organisms examined to date with putative functions ranging from the maintenance of…”
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Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells by Hambardikar, Vedangi, Guitart-Mampel, Mariona, Scoma, Ernest R, Urquiza, Pedro, Nagana, Gowda G A, Raftery, Daniel, Collins, John A, Solesio, Maria E

“…Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout evolution and present in all studied organisms. In mammals, it shows…”
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Mitochondrial Inorganic Polyphosphate (polyP) Is a Potent Regulator of Mammalian Bioenergetics in SH-SY5Y Cells: A Proteomics and Metabolomics Study by Guitart-Mampel, Mariona, Urquiza, Pedro, Carnevale Neto, Fausto, Anderson, James R, Hambardikar, Vedangi, Scoma, Ernest R, Merrihew, Gennifer E, Wang, Lu, MacCoss, Michael J, Raftery, Daniel, Peffers, Mandy J, Solesio, Maria E

“…Inorganic polyphosphate (polyP) is an ancient, ubiquitous, and well-conserved polymer which is present in all the studied organisms. It is formed by individual…”
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Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle by Da Costa, Renata T, Urquiza, Pedro, Perez, Matheus M, Du, YunGuang, Khong, Mei Li, Zheng, Haiyan, Guitart-Mampel, Mariona, Elustondo, Pia A, Scoma, Ernest R, Hambardikar, Vedangi, Ueberheide, Beatrix, Tanner, Julian A, Cohen, Alejandro, Pavlov, Evgeny V, Haynes, Cole M, Solesio, Maria E

“…The existing literature points towards the presence of robust mitochondrial mechanisms aimed at mitigating protein dyshomeostasis within the organelle…”
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Toolkit for cellular studies of mammalian mitochondrial inorganic polyphosphate by Hambardikar, Vedangi, Akosah, Yaw A, Scoma, Ernest R, Guitart-Mampel, Mariona, Urquiza, Pedro, Da Costa, Renata T, Perez, Matheus M, Riggs, Lindsey M, Patel, Rajesh, Solesio, Maria E

“…Inorganic polyphosphate (polyP) is an ancient polymer which is extremely well-conserved throughout evolution, and found in every studied organism. PolyP is…”
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Cannabidiol repairs behavioral and brain disturbances in a model of fetal alcohol spectrum disorder by Gasparyan, Ani, Navarro, Daniela, Navarrete, Francisco, Austrich-Olivares, Amaya, Scoma, Ernest R., Hambardikar, Vedangi D., Acosta, Gabriela B., Solesio, María E., Manzanares, Jorge

“…Fetal alcohol spectrum disorder (FASD) includes neuropsychiatric disturbances related to gestational and lactational ethanol exposure. Available treatments are…”
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Short‐term starvation activates AMPK and restores mitochondrial inorganic polyphosphate, but fails to reverse associated neuronal senescence by Tagliafico, Luca, Da Costa, Renata T., Boccia, Lavinia, Kavehmoghaddam, Sheida, Ramirez, Bryan, Tokarska‐Schlattner, Malgorzata, Scoma, Ernest R., Hambardikar, Vedangi, Bonfiglio, Tommaso, Caffa, Irene, Monacelli, Fiammetta, Schlattner, Uwe, Betley, J. Nicholas, Nencioni, Alessio, Solesio, Maria E.

“…Neuronal senescence is a major risk factor for the development of many neurodegenerative disorders. The mechanisms that drive neurons to senescence remain…”
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Is there a link between inorganic polyphosphate (polyP), mitochondria, and neurodegeneration? by Borden, Emily A., Furey, Matthew, Gattone, Nicholas J., Hambardikar, Vedangi D., Liang, Xiao Hua, Scoma, Ernest R., Abou Samra, Antonella, D-Gary, LaKeshia R., Dennis, Dayshaun J., Fricker, Daniel, Garcia, Cindy, Jiang, ZeCheng, Khan, Shariq A., Kumarasamy, Dheenadhayalan, Kuppala, Hasmitha, Ringrose, Savannah, Rosenheim, Evan J., Van Exel, Kimberly, Vudhayagiri, Hemanth Sai, Zhang, Jiarui, Zhang, Zhaowen, Guitart-Mampel, Mariona, Urquiza, Pedro, Solesio, Maria E.

“…[Display omitted] Mitochondrial dysfunction – including increased apoptosis, calcium and protein dyshomeostasis within the organelle, and dysfunctional…”
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