Search Results - "Scollo, Federica"
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Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins
Published in ACS chemical neuroscience (16-12-2020)“…An increasing number of human diseases has been shown to be linked to aggregation and amyloid formation by intrinsically disordered proteins (IDPs). Amylin,…”
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Amyloidogenic Intrinsically Disordered Proteins: New Insights into Their Self-Assembly and Their Interaction with Membranes
Published in Life (Basel, Switzerland) (08-08-2020)“…Aβ, IAPP, α-synuclein, and prion proteins belong to the amyloidogenic intrinsically disordered proteins’ family; indeed, they lack well defined secondary and…”
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Sensitivity of endogenous autofluorescence in HeLa cells to the application of external magnetic fields
Published in Scientific reports (04-07-2023)“…Dramatically increased levels of electromagnetic radiation in the environment have raised concerns over the potential health hazards of electromagnetic fields…”
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What Does Time-Dependent Fluorescence Shift (TDFS) in Biomembranes (and Proteins) Report on?
Published in Frontiers in chemistry (29-10-2021)“…The organization of biomolecules and bioassemblies is highly governed by the nature and extent of their interactions with water. These interactions are of high…”
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Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?
Published in Open biology (01-09-2024)“…Calmodulin (CaM) is a ubiquitous calcium-sensitive messenger in eukaryotic cells. It was previously shown that CaM possesses an affinity for diverse lipid…”
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Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Aβ and hIAPP
Published in Biochimica et biophysica acta. Biomembranes (01-09-2018)“…Alzheimer's Disease (AD) and Type 2 diabetes mellitus (T2DM) are two incurable diseases both hallmarked by an abnormal deposition of the amyloidogenic peptides…”
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A unifying framework for amyloid-mediated membrane damage: The lipid-chaperone hypothesis
Published in Biochimica et biophysica acta. Proteins and proteomics (01-04-2022)“…Over the past thirty years, researchers have highlighted the role played by a class of proteins or polypeptides that forms pathogenic amyloid aggregates in…”
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Calmodulin interactions with model lipid membranes: the interplay of Ca2+and lipid composition
Published in Biophysical journal (11-02-2022)Get full text
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Phospholipids Critical Micellar Concentrations Trigger Different Mechanisms of Intrinsically Disordered Proteins Interaction with Model Membranes
Published in The journal of physical chemistry letters (06-09-2018)“…Amyloidogenic proteins are involved in many diseases, including Alzheimer’s, Parkinson’s, and type II diabetes. These proteins are thought to be toxic for…”
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Cholesterol promotes clustering of PI(4,5)P2 driving unconventional secretion of FGF2
Published in The Journal of cell biology (07-11-2022)“…FGF2 is a cell survival factor involved in tumor-induced angiogenesis that is secreted through an unconventional secretory pathway based upon direct protein…”
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11
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?
Published in Open biology (01-01-2024)“…Calmodulin (CaM) is a ubiquitous calcium-sensitive messenger in eukaryotic cells. It was previously shown that CaM possesses an affinity for diverse lipid…”
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Ultrasensitive Detection and Wide Dynamic Range Pyrene Quantification Based on Luminescence Restoration of β‑Cyclodextrin-Functionalized Silicon Nanowires
Published in ACS applied nano materials (11-10-2024)“…This study presents a breakthrough in the detection of polycyclic aromatic hydrocarbons (PAHs), particularly pyrene, recognized as persistent organic…”
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New fluorescent-labelled nanoparticles: synthesis, characterization and interactions with cysteine and homocysteine to evaluate their stability in aqueous solution
Published in Applied nanoscience (01-04-2020)“…Fluorescent-labelled nanoparticles conjugate the SPR of nanomaterials as well as the fluorescence properties of the capping dye. In this work, we report a…”
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14
A unifying framework for amyloid-mediated membrane damage: The lipid-chaperon hypothesis
Published 20-12-2021“…Over the past thirty years, researchers have highlighted the role played by a class of proteins or polypeptides that forms pathogenic amyloid aggregates in…”
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