Search Results - "Scoggins, Matthew A."
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Hydroxyurea maintains working memory function in pediatric sickle cell disease
Published in PloS one (27-06-2024)“…Sickle cell disease (SCD) decreases the oxygen-carrying capacity of red blood cells. Children with SCD have reduced/restricted cerebral blood flow, resulting…”
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Clinical utility of the N-back task in functional neuroimaging studies of working memory
Published in Journal of clinical and experimental neuropsychology (14-09-2014)“…Introduction: N-back tasks are commonly used in functional neuroimaging studies to identify the neural mechanisms supporting working memory (WM). Despite…”
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Functional MRI Assessment of Brain Activity Patterns Associated with Reading in Medulloblastoma Survivors
Published in Brain sciences (06-09-2024)“…Medulloblastoma, a malignant brain tumor primarily affecting children, poses significant challenges to patients and clinicians due to its complex treatment and…”
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4
Cerebellar mutism is linked to midbrain volatility and desynchronization from speech cortices
Published in Brain (London, England : 1878) (02-11-2023)“…Abstract Cerebellar mutism syndrome is a disorder of speech, movement and affect that can occur after tumour removal from the posterior fossa. Projections from…”
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Computerized Cognitive Training for Amelioration of Cognitive Late Effects Among Childhood Cancer Survivors: A Randomized Controlled Trial
Published in Journal of clinical oncology (20-11-2015)“…Children receiving CNS-directed therapy for cancer are at risk for cognitive problems, with few available empirically supported interventions. Cognitive…”
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Fastigial nuclei surgical damage and focal midbrain disruption implicate PAG survival circuits in cerebellar mutism syndrome
Published in Neuro-oncology (Charlottesville, Va.) (14-02-2023)“…Pediatric postoperative cerebellar mutism syndrome (CMS) is a rare but well-known complication of medulloblastoma (Mb) resection with devastating effects on…”
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Developmental patterns of CBF and BOLD responses to visual stimulus
Published in Journal of cerebral blood flow and metabolism (01-03-2021)“…To investigate the developmental changes of cerebral blood flow (CBF) and hemodynamic responses to changing neural activity, we used the arterial spin label…”
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Secondary cerebro-cerebellar and intra-cerebellar dysfunction in cerebellar mutism syndrome
Published in Neuro-oncology (Charlottesville, Va.) (05-09-2024)“…Abstract Background Cerebellar mutism syndrome (CMS) is characterized by deficits of speech, movement, and affect that can occur following tumor removal from…”
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Brain Activity Associated With Attention Deficits Following Chemotherapy for Childhood Acute Lymphoblastic Leukemia
Published in JNCI : Journal of the National Cancer Institute (01-02-2019)“…The impact of contemporary chemotherapy treatment for childhood acute lymphoblastic leukemia on central nervous system activity is not fully appreciated…”
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10
CT-Based Modeling of the Dentition for Craniomaxillofacial Surgical Planning
Published in The Journal of craniofacial surgery (01-07-2022)“…Historically, the accuracy of imaging teeth by computed tomography (CT) has been suboptimal and deemed inadequate for surgical planning of orthognathic…”
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Neuroanatomical abnormalities related to dexamethasone exposure in survivors of childhood acute lymphoblastic leukemia
Published in Pediatric blood & cancer (01-03-2020)“…Survivors of childhood acute lymphoblastic leukemia (ALL) treated with chemotherapy only are at risk for neurocognitive impairment. Regions of interest were…”
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Automatic detection and segmentation of postoperative cerebellar damage based on normalization
Published in Neuro-oncology advances (01-01-2023)“…Abstract Background Surgical resection is the gold standard in the treatment of pediatric posterior fossa tumors. However, surgical damage is often unavoidable…”
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Structural and Functional Brain Imaging in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia Treated With Chemotherapy: A Systematic Review
Published in JNCI cancer spectrum (01-10-2021)“…The effect of chemotherapy on brain development in long-term survivors of pediatric acute lymphoblastic leukemia (ALL) was systematically reviewed. A…”
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Cerebral microbleeds in adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation
Published in Scientific reports (20-01-2020)“…Cranial radiation therapy is associated with white matter-specific brain injury, cortical volume loss, mineralization, microangiopathy and neurocognitive…”
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Investigating the Role of Hypothalamic Tumor Involvement in Sleep and Cognitive Outcomes Among Children Treated for Craniopharyngioma
Published in Journal of pediatric psychology (01-07-2016)“…Despite excellent survival prognosis, children treated for craniopharyngioma experience significant morbidity. We examined the role of hypothalamic involvement…”
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Dexamethasone exposure and memory function in adult survivors of childhood acute lymphoblastic leukemia: A report from the SJLIFE cohort
Published in Pediatric blood & cancer (01-11-2013)“…Background Dexamethasone is used in acute lymphoblastic leukemia (ALL) treatment, though long‐term impact on central nervous system (CNS) function is unclear…”
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Genetic variants, neurocognitive outcomes, and functional neuroimaging in survivors of childhood acute lymphoblastic leukemia
Published in JNCI cancer spectrum (03-07-2023)“…Abstract Background Genetic predispositions may modulate risk for developing neurocognitive late effects in childhood acute lymphoblastic leukemia (ALL)…”
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Sex-Based Differences in Functional Brain Activity During Working Memory in Survivors of Pediatric Acute Lymphoblastic Leukemia
Published in JNCI cancer spectrum (02-03-2022)“…Long-term survivors of pediatric acute lymphoblastic leukemia are at elevated risk for neurocognitive deficits and corresponding brain dysfunction. This study…”
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Connectivity of the Cerebello-Thalamo-Cortical Pathway in Survivors of Childhood Leukemia Treated With Chemotherapy Only
Published in JAMA network open (02-11-2020)“…Treatment with contemporary chemotherapy-only protocols is associated with risk for neurocognitive impairment among survivors of childhood acute lymphoblastic…”
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Functional MRI in medulloblastoma survivors supports prophylactic reading intervention during tumor treatment
Published in Brain imaging and behavior (01-03-2016)“…Development of reading skills is vulnerable to disruption in children treated for brain tumors. Interventions, remedial and prophylactic, are needed to…”
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