Search Results - "Sciurba, Frank C."
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An official European Respiratory Society/American Thoracic Society technical standard: field walking tests in chronic respiratory disease
Published in The European respiratory journal (01-12-2014)“…Field walking tests are commonly employed to evaluate exercise capacity, assess prognosis and evaluate treatment response in chronic respiratory diseases. In…”
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Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease
Published in The New England journal of medicine (26-10-2017)“…In this trial evaluating mepolizumab, an anti–interleukin-5 antibody, the rate of COPD exacerbations among patients whose COPD was characterized by an…”
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An official systematic review of the European Respiratory Society/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease
Published in The European respiratory journal (01-12-2014)“…This systematic review examined the measurement properties of the 6-min walk test (6MWT), incremental shuttle walk test (ISWT) and endurance shuttle walk test…”
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A Randomized Study of Endobronchial Valves for Advanced Emphysema
Published in The New England journal of medicine (23-09-2010)“…One of the characteristics of severe emphysema is hyperinflation of regions of the lungs. In this trial, valves that prevented air entry but allowed air to…”
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Respiratory symptoms and airway obstruction in HIV-infected subjects in the HAART era
Published in PloS one (21-07-2009)“…Prevalence and risk factors for respiratory symptoms and airway obstruction in HIV-infected subjects in the era of highly active antiretroviral therapy (HAART)…”
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Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis
Published in American journal of respiratory and critical care medicine (01-12-2014)“…Idiopathic pulmonary fibrosis (IPF) is an untreatable and often fatal lung disease that is increasing in prevalence and is caused by complex interactions…”
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Identification of factors directly linked to incident chronic obstructive pulmonary disease: A causal graph modeling study
Published in PLoS medicine (13-08-2024)“…Beyond exposure to cigarette smoking and aging, the factors that influence lung function decline to incident chronic obstructive pulmonary disease (COPD)…”
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Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
Published in PloS one (02-10-2008)“…Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by abnormal cellular responses to cigarette smoke, resulting in tissue…”
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A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation
Published in Nature immunology (01-05-2013)“…Inflammation needs to be tightly regulated to avoid immunopathology. Mallampalli and colleagues show that a system of F box proteins tunes proinflammatory…”
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Optimal threshold in CT quantification of emphysema
Published in European radiology (01-04-2013)“…Objectives To determine the optimal threshold by quantitatively assessing the extent of emphysema at the level of the entire lung and at the level of…”
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The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
Published in The New England journal of medicine (24-06-2004)“…Physiological observations indicate that the small airways are the predominant site of airway obstruction in patients with chronic obstructive pulmonary…”
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Plasma B lymphocyte stimulator and B cell differentiation in idiopathic pulmonary fibrosis patients
Published in The Journal of immunology (1950) (01-09-2013)“…We hypothesized B cells are involved in the pathogenesis of idiopathic pulmonary fibrosis (IPF), a progressive, restrictive lung disease that is refractory to…”
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Pulmonary Function Abnormalities in HIV-Infected Patients during the Current Antiretroviral Therapy Era
Published in American journal of respiratory and critical care medicine (15-09-2010)“…Before the introduction of combination antiretroviral (ARV) therapy, patients infected with HIV had an increased prevalence of respiratory symptoms and lung…”
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Incident low muscle mass is associated with greater lung disease and lower circulating leptin in a tobacco-exposed longitudinal cohort
Published in Respiratory research (22-09-2023)“…Muscle loss is prevalent in chronic obstructive pulmonary disease (COPD). Prior studies evaluating musculoskeletal dysfunction in COPD have focused on…”
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Cell-free DNA levels associate with COPD exacerbations and mortality
Published in Respiratory research (18-01-2024)“…Good biological indicators capable of predicting chronic obstructive pulmonary disease (COPD) phenotypes and clinical trajectories are lacking. Because nuclear…”
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Much lower prevalence and mortality of chronic obstructive pulmonary disease in Japan than in the US despite higher smoking rates: A meta analysis/systematic review
Published in Journal of Epidemiology (2024)“…Background: A recent systematic review showed Japan's mortality from chronic obstructive pulmonary disease (COPD) is the lowest among 204 countries, despite…”
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Identification of Early Interstitial Lung Disease in Smokers from the COPDGene Study
Published in Academic radiology (01-01-2010)“…Rationale and Objectives The aim of this study is to compare two subjective methods for the identification of changes suggestive of early interstitial lung…”
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Airflow Limitation and Endothelial Dysfunction. Unrelated and Independent Predictors of Atherosclerosis
Published in American journal of respiratory and critical care medicine (01-07-2016)“…Lower FEV1 is associated with increased prevalence of atherosclerosis; however, causal mechanisms remain elusive. To determine if systemic endothelial…”
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Interstitial Lung Abnormalities and Reduced Exercise Capacity
Published in American journal of respiratory and critical care medicine (01-04-2012)“…The relationship between interstitial lung abnormalities (ILA) and exercise capacity has not been comprehensively evaluated. To assess the validity of the…”
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Radiographic Emphysema Predicts Low Bone Mineral Density in a Tobacco-exposed Cohort
Published in American journal of respiratory and critical care medicine (01-04-2011)“…Studies demonstrating an association between chronic obstructive pulmonary disease and low bone mineral density (BMD) implicate factors distinct from…”
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