Search Results - "Scipioni, Matteo"

Structural insights of sulfonamide-based NLRP3 inflammasome inhibitors: design, synthesis, and biological characterization by Xu, Yiming, Scipioni, Matteo, Blevins, Hallie, Zhang, Shijun

“…NLRP3 inflammasome has recently attracted much attention as a potentially druggable target to develop potential therapeutics for inflammatory and…”
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Novel vanillin derivatives: Synthesis, anti-oxidant, DNA and cellular protection properties by Scipioni, Matteo, Kay, Graeme, Megson, Ian, Kong Thoo Lin, Paul

“…Antioxidants have been the subject of intense research interest mainly due to their beneficial properties associated with human health and wellbeing. Phenolic…”
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P-23 - Novel vanillin derivatives: An insight into their antioxidant properties by Scipioni, Matteo, Kay, Graeme, Megson, Ian, Lin, Paul Kong Thoo

“…Oxidative stress, the unbalance between the occurrence of oxygen/nitrogen reactive species (ROS and RNS) and the ability of the organism to inactivate these…”
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Novel vanillin derivatives: An insight into their antioxidant properties by Scipioni, Matteo, Kay, Graeme, Megson, Ian, Lin, Paul Kong Thoo

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Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease by Scipioni, Matteo, Kay, Graeme, Megson, Ian L, Kong Thoo Lin, Paul

“…Alzheimer's disease (AD) is the most common cause of dementia worldwide, normally affecting people aged over 65. Due to the multifactorial nature of this…”
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Synthesis of Novel Vanillin Derivatives : Study of Their Antioxidant and Potential Neuroprotective Properties by Scipioni, Matteo

“…Vanillin (4-hydroxy-3-methoxybenzaldehyde) is a naturally-occurring phenolic compound, forming the main component of the bean and pod of vanilla orchids. It is…”
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Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9md00048h by Scipioni, Matteo, Kay, Graeme, Megson, Ian L., Kong Thoo Lin, Paul

“…Novel vanillin–tacrine hybrid acting as AChE and Aβ (1–42) amyloid aggregation inhibitor with strong antioxidant properties enhanced by the p -phenylenediamine…”
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