Search Results - "Sciorati, C."
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Cell death, clearance and immunity in the skeletal muscle
Published in Cell death and differentiation (01-06-2016)“…The skeletal muscle is an immunologically unique tissue. Leukocytes, virtually absent in physiological conditions, are quickly recruited into the tissue upon…”
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Immunomodulation induced by EUS-ablation with hybridtherm-probe in locally advanced and borderline resectable pancreatic cancer: results from a phase II randomized controlled trial
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-07-2021)Get full text
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P.11.2 Naproxcinod, a nitric oxide-donating anti-inflammatory compound, is effective in two mouse models of muscle dystrophy
Published in Neuromuscular disorders : NMD (01-10-2013)“…Nitric oxide (NO) plays a critical role in skeletal muscle function, including control of blood flow and muscle repair. In muscular dystrophies, synthesis of…”
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Inhibition of Caspase-1-Like Activity by Ac-Tyr-Val-Ala-Asp-Chloromethyl Ketone Induces Long-Lasting Neuroprotection in Cerebral Ischemia through Apoptosis Reduction and Decrease of Proinflammatory Cytokines
Published in The Journal of neuroscience (15-06-2000)“…Broad spectrum caspase inhibitors have been found to reduce neurodegeneration caused by cerebral ischemia. We studied whether blockade of group I caspases,…”
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PTX3 as a novel inflammatory biomarker in patients with myocarditis
Published in European heart journal (03-10-2022)“…Abstract Background Pentraxin-3 (PTX3) is an acute phase protein, which plays pivotal roles in innate immunity and inflammation. Among cardiovascular diseases,…”
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Growth factor-induced Ca2+ responses are differentially modulated by nitric oxide via activation of a cyclic GMP-dependent pathway
Published in Molecular pharmacology (01-12-1995)“…Nitric oxide (NO) plays a modulatory role on cell growth and differentiation, biological processes that occur under the control of various signal transduction…”
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Dipeptidyl peptidase 4/CD26 expression in human idiopathic inflammatory myopathies reveals skeletal muscle injury and vascular inflammation
Published in Clinical and experimental rheumatology (01-02-2022)“…We performed a retrospective and prospective observational study to investigate whether the T lymphocyte activation antigen dipeptidyl peptidase 4 (DPP4)/CD26…”
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Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide
Published in Science (American Association for the Advancement of Science) (07-02-2003)“…Nitric oxide was found to trigger mitochondrial biogenesis in cells as diverse as brown adipocytes and 3T3-L1, U937, and HeLa cells. This effect of nitric…”
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Flow cytometric analysis of inflammatory cells in ischemic rat brain
Published in Stroke (1970) (01-02-2002)“…Inflammation plays a key role in cerebral ischemia through activation of microglia and infiltration by leukocytes. Flow cytometry is a well-established method…”
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Nitric oxide modulation of agonist-evoked intracellular Ca2+ release in neurosecretory PC-12 cells: inhibition of phospholipase C activity via cyclic GMP-dependent protein kinase I
Published in Molecular pharmacology (01-03-1995)“…Nitric oxide is a signaling molecule involved in events crucial to neuronal cell function, such as neurotransmitter release, gene transcription, and…”
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Wild-Type Huntingtin Protects from Apoptosis Upstream of Caspase-3
Published in The Journal of neuroscience (15-05-2000)“…Expansion of a polyglutamine sequence in the N terminus of huntingtin is the gain-of-function event that causes Huntington's disease. This mutation affects…”
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Activation of Acid Sphingomyelinase and Its Inhibition by the Nitric Oxide/Cyclic Guanosine 3',5'-Monophosphate Pathway: Key Events in Escherichia coli-Elicited Apoptosis of Dendritic Cells
Published in The Journal of immunology (1950) (01-10-2004)“…Depletion of dendritic cells (DCs) via apoptosis contributes to sepsis-induced immune suppression. The mechanisms leading to DC apoptosis during sepsis are not…”
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MICA Expressed by Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance Plasma Cells Costimulates Pamidronate-Activated gamma delta Lymphocytes
Published in Cancer research (Chicago, Ill.) (15-08-2005)“…Amino-biphosphonates (like pamidronate) activate human V gamma 9/V delta 2 T lymphocytes and promote their cytotoxicity against multiple myeloma cells. T-cell…”
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Autocrine nitric oxide modulates CD95-induced apoptosis in gamma delta T lymphocytes
Published in The Journal of biological chemistry (12-09-1997)“…gamma delta T lymphocytes play an important early role in the defense against pathogens. Their function is terminated by acquisition of susceptibility to…”
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Nitric Oxide Inhibits Tumor Necrosis factor-α -Induced Apoptosis by Reducing the Generation of Ceramide
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-2000)“…Apoptosis triggered by death receptors proceeds after defined signal-transduction pathways. Whether signaling at the receptor level is regulated by…”
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Nitric oxide confers therapeutic activity to dendritic cells in a mouse model of melanoma
Published in Cancer research (Chicago, Ill.) (01-06-2004)“…Susceptibility of dendritic cells (DCs) to tumor-induced apoptosis reduces their efficacy in cancer therapy. Here we show that delivery within exponentially…”
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Nitric oxide, ceramide and sphingomyelinase-coupled receptors: A tale of enzymes and messengers coordinating cell death, survival and differentiation
Published in Life sciences (1973) (19-08-2005)“…The gaseous messenger nitric oxide plays a role in a variety of biological functions. Evidence accumulated over the last 7 years indicates that functions of…”
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Effects of nitric oxide on proliferation and differentiation of rat brown adipocytes in primary cultures
Published in British journal of pharmacology (01-10-1998)“…1 In the present work, we study the effect of NO on the proliferation and differentiation of brown fat cells in primary cultures. 2 Brown fat precursor cells…”
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